Email this article The pathomorphological characteristics of clear-cell adenocarcinomas of the ovary and its mixed tumors with a clear-cell component
- Authors: Akhmedova M.D1, Shabanov M.A.1, Barinov V.V.1, Zhordania K.I.1, Bokina L.I.1, Mustafina E.A.1
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Affiliations:
- N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
- Issue: No 1 (2011)
- Pages: 70-75
- Section: GYNECOLOGY. DIAGNOSIS
- Published: 25.02.2011
- URL: https://ojrs.abvpress.ru/ojrs/article/view/146
- DOI: https://doi.org/10.17650/1994-4098-2011-0-1-70-75
- ID: 146
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Abstract
Objective: to study the pathomorphological signs of pure and mixed clear-cell ovarian tumors with a clear-cell component.
Subjects and methods. The clinical and morphological characteristics and the course of the disease were analyzed in 96 patients aged 21 to 75 years with clear-cell ovarian carcinoma. All the patients were divided into 2 groups: 1) 71 patients with pure clear-cell ovarian adenocarcinomas (COA) and 2) 25 patients with mixed malignant ovarian epithelial tumors (MMOET) with an obligatory clear-cell component. All pure forms of ovarian clear-cell malignancies were represented by adenocarcinoma in our study. This histologic type of the tumor was also prevalent among mixed ovarian neoplasms.
Results. Clear, optically transparent cells and shoe nail-type (nail) ones were most common in COA. MMOETs showed moderate dif- ferentiation and malignancy and moderate atypia of a cell. Pure clear-cell neoplasms generally displayed 3 to 6 mitoses in 10 fields of vision whereas MMOET exhibited as many as 3 mitoses in 10 fields of vision.
About the authors
M.. D Akhmedova
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowRussian Federation
M. A. Shabanov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowRussian Federation
V. V. Barinov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowRussian Federation
K. I. Zhordania
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowRussian Federation
L. I. Bokina
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowRussian Federation
E. A. Mustafina
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Author for correspondence.
Email: afl_nlo154@mail.ru
Russian Federation
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