Email this article Epithelioid trophoblastic tumor: Clinical presentation, diagnosis, and treatment
- Authors: Lisayev D.A.1, Toloknov B.O.1, Makhova E.E.1, Markina I.V.1
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Affiliations:
- N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Department of Oncology, Moscow State University of Medicine and Dentistry
- Issue: No 2 (2010)
- Pages: 84-88
- Section: GYNECOLOGY. TREATMENT
- Published: 27.05.2010
- URL: https://ojrs.abvpress.ru/ojrs/article/view/236
- DOI: https://doi.org/10.17650/1994-4098-2010-0-2-84-88
- ID: 236
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Abstract
Epithelioid trophoblastic tumor (ETT) is a rare form of trophoblastic disease, which is characterized by high malignancy and a number of diagnostic features: a long interval between the last pregnancy and labor and the onset of the disease; a visual pattern at gynecological examination, relatively low β-chorionic gonadotropin (CG) levels, as well as the diffuse expression of cytokeratins-7 (+++) and -18 (+++), р63 (nuclear ++), E-cadherin (+++), EGFR (+), and CD-117(++) by tumor cells, as determined by immunohistochemical assay, and focal expression of CG (++) and PLAP (+) by these cells.
About the authors
D. A. Lisayev
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Department of Oncology, Moscow State University of Medicine and Dentistry
Author for correspondence.
Email: lisaev84@mail.ru
Russian Federation
B. O. Toloknov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Department of Oncology, Moscow State University of Medicine and DentistryRussian Federation
E. E. Makhova
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Department of Oncology, Moscow State University of Medicine and DentistryRussian Federation
I. V. Markina
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Department of Oncology, Moscow State University of Medicine and DentistryRussian Federation
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