SPECIFIC FEATURE OF HORMONAL PROFILE IN PATIENTS WITH PRIMARY AND RECURRENT BREAST CANCER AND THEIR ROLE IN THE EFFICIENCY OF CHEMOTHERAPY

M. B. Kozlova; Козлова М. Б.; E. M. Frantziyantz; Франциянц Е. М.; G. A. Nerodo; Неродо Г. А.; R. N. Salatov; Салатов Р. Н.; R. G. Luganskaya; Луганская Р. Г.; I. P. Sidorenko; Сидоренко И. П.; M. V. Kashubina; Кашубина М. В.

doi:10.17650/1994-4098-2009-0-1-2-29-33

SPECIFIC FEATURE OF HORMONAL PROFILE IN PATIENTS WITH PRIMARY AND RECURRENT BREAST CANCER AND THEIR ROLE IN THE EFFICIENCY OF CHEMOTHERAPY

Authors: Kozlova M.B.¹, Frantziyantz E.M.¹, Nerodo G.A.¹, Salatov R.N.¹, Luganskaya R.G.¹, Sidorenko I.P.¹, Kashubina M.V.¹
Affiliations:
1. Rostov Cancer Research Institute, Russian Agency for Medical Technologies
Issue: No 1-2 (2009)
Pages: 29-33
Section: MAMMOLOGY. TREATMENT
Published: 01.05.2009
URL: https://ojrs.abvpress.ru/ojrs/article/view/286
DOI: https://doi.org/10.17650/1994-4098-2009-0-1-2-29-33
ID: 286

Cite item

Full Text

Abstract
About the authors
References
Supplementary files
Statistics

Abstract

The hormonal background was studied in 32 menopausal patients who had primary breast cancer (Stage III) or its recurrence in the postoperative scar. The patients with the primary process, unlike those with a recurrence, were found to have increased adrenocortical cortisol-forming activity and changed thyroid homeostasis. In both types of the neoplastic process, the blood concentrations of estradi- ol, testosterone, prolactin, follicle-stimulating and luteinizing hormones were disturbed in a substantial number of cases; the distinc- tive feature of the primary process and its recurrence lies in the opposite direction. An association of individual differences in the con- centrations of estradiol and testosterone with the efficiency of neoadjuvant chemotherapy was analyzed in patients with recurrent can- cer.

Keywords

breast cancer, recurrence, hormonal profile, chemotherapy

References

Supplementary files

Supplementary Files

Action

1. JATS XML

Download

Username
Password
Remember me

Forgot password?	Register

Username
Password
Remember me

Forgot password?	Register

SPECIFIC FEATURE OF HORMONAL PROFILE IN PATIENTS WITH PRIMARY AND RECURRENT BREAST CANCER AND THEIR ROLE IN THE EFFICIENCY OF CHEMOTHERAPY

Full Text

Abstract

Keywords

About the authors

M. B. Kozlova

E. M. Frantziyantz

G. A. Nerodo

R. N. Salatov

R. G. Luganskaya

I. P. Sidorenko

M. V. Kashubina

References

Supplementary files