Hereditary breast cancer and ovarian cancer: clinical course and treatment

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Abstract

This article analyzes current problems associated with surgical and systemic treatment for hereditary breast and ovarian cancers (including those associated with BRCA1/2 gene mutations). We discuss the issues related to clinical course of multiple primary tumors and their sensitivity to cytostatic and targeted therapy.

About the authors

V. V. Semiglazov

I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia; N.N. Petrov National Medical Research Center of Oncology, Ministry of Health of Russia

Author for correspondence.
Email: oncology.spbgmu@mail.ru
ORCID iD: 0000-0002-8825-5221

6–8 Lva Tolstogo St., Saint Petersburg 197022

68 Leningradskaya St.,  Pesochnyy Settlement, Saint Petersburg 197758

Russian Federation

A. Е. Protasova

Saint-Petersburg State University

7–9 Universitetskaya Naberezhnaya, Saint-Petersburg 199034 Russian Federation

G. K. Kalikeev

I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia

6–8 Lva Tolstogo St., Saint Petersburg 197022 Russian Federation

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 36991 от  21.07.2009.