State of the balance of sexual steroids in the patients with cancer of the body of the uterus of young age

Peculiar properties of balance of sexual steroids prior to medical treatment are studied on 87 patients sick of uterus cancer. The first group consists of 32 women younger than 35 years, the second — of 55 patients aged 38–45 years. Along with decrease of excretion of the absolute level of estrogens, progestins, and androgens in both groups, in the first group the balance deviations of estrogen fractions towards prevalence of the sum of estron and estradiol over estriol are revealed. In the second group (38–45 years) estriol is dominating in the ratio of estrogenic fractions. In both groups the quantity of pregnandiol is reduced along with shift of balance estradiol / pregnandiol towards estradiol.

cancer of uterus, reproductive period, sexual hormones, estron, estradiol, pregnandiol