Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press107310.17650/1994-4098-2023-19-1-24-29MAMMOLOGY. REVIEWSМАММОЛОГИЯ. ОБЗОРНЫЕ СТАТЬИUtility of radiotherapy for the management of local tumor progression in patients with early breast cancerВозможности лучевой терапии в контроле регионарного прогрессирования при раннем раке молочной железыhttps://orcid.org/0000-0002-2481-0791GladilinaI.  A. ГладилинаИ. А.
Russian Federation

Irina Anatolyevna Gladilina

115522

23 Kashirskoe Shosse

117997

1 Ostrovityanova St.

Moscow

Ирина Анатольевна Гладилина

115478

Каширское шоссе, 23

117997

ул. Островитянова, 1

Москва

0152@mail.ruhttps://orcid.org/0000-0001-8814-636XVysotskayaI.  V. ВысоцкаяИ. В.
Russian Federation

119991

Build. 2, 8 Trubetskaya St.

Moscow

119991

ул. Трубецкая, 8, стр. 2

Москва

https://orcid.org/0000-0003-4412-5019ChulkovaS.  V. ЧулковаС. В.
Russian Federation

115522

23 Kashirskoe Shosse

117997

1 Ostrovityanova St.

Moscow

115478

Каширское шоссе, 23

117997

ул. Островитянова, 1

Москва

https://orcid.org/0000-0003-3904-8530EgorovaA.  V. ЕгороваА. В.
Russian Federation

117997

1 Ostrovityanova St.

Moscow

117997

ул. Островитянова, 1

Москва

https://orcid.org/0000-0002-7090-7447 ShabanovM. A.ШабановМ. А.
Russian Federation

115522

23 Kashirskoe Shosse

Moscow

115478

Каширское шоссе, 23

Москва

https://orcid.org/0000-0001-5231-9927FedoseenkoD.  I. ФедосеенкоД. И.
Russian Federation

115522

23 Kashirskoe Shosse

Moscow

115478

Каширское шоссе, 23

Москва

https://orcid.org/0000-0001-6148-8933SemichevD.  G. СемичевД. Г.
Russian Federation

117997

1 Ostrovityanova St.

Moscow

117997

ул. Островитянова, 1

Москва

National Medical Research Center of Oncology named after N. N. Blokhin, Ministry of Health of RussiaФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Блохина» Минздрава РоссииN. I. Pirogov Russian National Research Medical University, Ministry of Health of RussiaФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н. И. Пирогова» Минздрава РоссииI. M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaФГАОУ ВО «Первый Московский государственный медицинский университет им. И. М. Сеченова» Минздрава России2606202319124292406202324062023https://ojrs.abvpress.ru/ojrs/article/view/1073

   The generally accepted standard in early breast cancer surgery today is breast-conserving surgery with external beam radiation therapy, which is comparable in results to previously widely performed radical mastectomy and even has an advantage in terms of overall survival and control. Until now, there are areas of discussion and a number of questions remain related to the methodology of irradiation of patients with breast cancer, namely: is it advisable to irradiate the axillary zone after radical resection for early breast cancer? Does irradiation of axillary lymph nodes provide regional control comparable to lymphadenectomy, and whether it can be an alternative to lymph node dissection? Whether provides an irradiation of axillary lymph nodes comparable with regional lymph node dissection the control over patients with a positive sentry lymph node? A lot of studies have been published so far, answers to questions derived from what we present in this work.

   Общепринятым стандартом в хирургии раннего рака молочной железы (РМЖ) в настоящее время является органосохраняющая операция с последующей дистанционной лучевой терапией и системной терапией. Согласно результатам исследований, органосохраняющие операции имеют преимущество по показателям общей выживаемости и уровню локального контроля. До настоящего времени предметом активной дискуссии остается ряд вопросов, связанных с методологией облучения пациенток с РМЖ. Целесообразно ли облучение аксиллярной зоны после радикальной резекции по поводу раннего РМЖ? Обеспечивает ли облучение аксиллярных лимфатических узлов сопоставимый с лимфодиссекцией регионарный контроль и может ли быть альтернативой лимфодиссекции у больных ранним РМЖ без клинических признаков регионарных метастазов (N0)? Обеспечивает ли облучение аксиллярных лимфатических узлов сопоставимый с лимфодиссекцией регионарный контроль у больных с метастазами в сторожевые лимфатические узлы? К настоящему времени опубликовано множество исследований, содержащих ответы на эти вопросы, основные из которых мы приводим в данной работе.

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