Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press1110.17650/1994-4098-2014-0-1-49-57MAMMOLOGY. TREATMENTМАММОЛОГИЯ. ЛЕЧЕНИЕOptimization of indications for parasternal radiotherapy in patients with breast cancerОптимизация показаний для проведения лучевой терапии на парастернальную зону у больных раком молочной железыZaytcevaA. A.ЗайцеваА. А.
Russian Federation
dr.zaytseva@mail.ruPetrovskyA. V.ПетровскийА. В.
Russian Federation
UymanovV. A.УймановВ. А.
Russian Federation
TrigolosovA. V.ТриголосовА. В.
Russian Federation
VishnevskayaYa. V.ВишневскаяЯ. В.
Russian Federation
GladilinaI. A.ГладилинаИ. А.
Russian Federation
AfanasyevaK. V.АфанасьеваК. В.
Russian Federation
MaslyankinD. B.МаслянкинД. Б.
Russian Federation
PolikarpovaS. B.ПоликарповаС. Б.
Russian Federation
NechushkinM. I.НечушкинМ. И.
Russian Federation
I.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава РоссииN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowФГБУ «РОНЦ им. Н.Н. Блохина» РАМН, Москва17072014149571707201417072014https://ojrs.abvpress.ru/ojrs/article/view/11

Detection of regional lymph nodes involvement is an extremely important step in the diagnosis and treatment of breast cancer. As with axillary lymph node metastases, parasternal lymph nodes metastases are an important prognostic factor. 1125 patients with breast cancer were under- went to thoracoscopicinternal mammary lymphadenectomy. Metastases were found in 204 of 1125 cases (18,3 %), representing 33,9 % of all cases of regional metastases (n = 601). Median overall survival in patients with internal mammary lymph nodes metastases who received radiation therapy and appropriate systemic treatment was 7,8 years, which is contrary to the earlier experience and is consistent with the results of the last years publications. We believe this excellent result is due to irradiation of the internal mammary nodes, and we believe that the thoracoscopic internal mammary lymphadenectomy should be a part of the diagnostic process in patients with breast cancer.

Определение объема поражения региональных лимфатических узлов (ЛУ) является важным этапом в лечении рака молочной железы (РМЖ). Метастазы в парастернальные и подмышечные ЛУ являются важным прогностическим фактором. Торакоскопическая парастернальная лимфаденэктомия (ТПЛАЭ) была выполнена 1125 больным РМЖ. Метастазы были обнаружены в 204 (18,3 %) из 1125 случаев, что составляет 33,9 % всех случаев выявления региональных метастазов (n = 601). Медиана общей продолжительности жизни пациентов с метастазами в парастернальные ЛУ, которые получали лучевую терапию и соответствующее системное лечение, составила 7,8 года. Мы считаем, что этот положительный результат связан с проведением лучевой терапии на область внутренних грудных ЛУ, и полагаем, что ТПЛАЭ должна быть частью диагностического процесса у больных РМЖ.

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