Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press12210.17650/1994-4098-2012-0-3-4-99-101GYNECOLOGY. DIAGNOSISГИНЕКОЛОГИЯ. ДИАГНОСТИКАRisk factors for recurrence in patients with virilizing ovarian tumorsФакторы риска возникновения рецидива у пациенток с вирилизирующими опухолями яичниковCherepanovaE. V.ЧерепановаЕ. В.
Russian Federation
katerinochka-k@rambler.ruLaktionovK. P.ЛактионовК. П.
Russian Federation
AnurovaO. A.АнуроваО. А.
Russian Federation
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowФГБУ «РОНЦ им. Н.Н. Блохина» РАМН, Москва240920123-49910124072014240720142012https://ojrs.abvpress.ru/ojrs/article/view/122

The paper presents the clinical, morphological, and immunohistochemical characteristics of virilizing ovarian tumors in 53 patients treated at the N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, from 1967 to 2010. The impact of the immu- nophenotype of virilizing ovarian tumor cells, clinical and morphological parameters, and performed treatment on the risk of recurrence has been studied in patients with virilizing ovarian tumors.

В статье представлены клинико-морфологические и иммуногистохимические характеристики вирилизирующих опухолей яичников 53 пациенток, находившихся на лечении в ФГБУ «РОНЦ им. Н.Н. Блохина» РАМН с 1967 по 2010 г. Изучено влияние иммунофенотипа клеток вирилизирующих опухолей яичников, клинико-морфологических параметров и проведенного лечения на риск возникновения рецидива у пациенток с вирилизирующими опухолями яичников.

virilizing ovarian tumorsvirilizationhormone-producing tumorsвирилизирующие опухоли яичниковвирилизациягормонопродуцирующие опухоли1. Ross L.D. Hilus cell tumour of the ovary with an associated endometrial carcinoma, presenting with male pattern baldness and postmenopausal bleeding. Case report. British J Obstetrics and Gynecol 1984;91:1266−8.Ross L.D. Hilus cell tumour of the ovary with an associated endometrial carcinoma, presenting with male pattern baldness and postmenopausal bleeding. Case report. British J Obstetrics and Gynecol 1984;91:1266−8.2. Choong C.S., Fuller P.J., Chu S. et al. Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant. J Clin Endocrin Metabol 2002;87(1): 49−56.Choong C.S., Fuller P.J., Chu S. et al. Sertoli-Leydig cell tumor of the ovary, a rare cause of precocious puberty in a 12-month-old infant. J Clin Endocrin Metabol 2002;87(1): 49−56.3. Ilhan R., Tuzlali S., Iplikci A. et al. Ovarian Sertoli-Leydig cell tumor with predominant retiform differentiation. The Turkish Journal of Pathology 1991;7(2):41−3.Ilhan R., Tuzlali S., Iplikci A. et al. Ovarian Sertoli-Leydig cell tumor with predominant retiform differentiation. The Turkish Journal of Pathology 1991;7(2):41−3.4. Sharma P.K., Joshi S. Steroid cell ovarian tumor: a case report of an unusual condition. NJOG 2009;4(1):52−4Sharma P.K., Joshi S. Steroid cell ovarian tumor: a case report of an unusual condition. NJOG 2009;4(1):52−45. Metzinger D.S., Webb M.J. Surgical man- agement of Sertoli-Leydig cell tumors of the ovary. CME J Gynecol Oncol 2002;7:140−2.Metzinger D.S., Webb M.J. Surgical man- agement of Sertoli-Leydig cell tumors of the ovary. CME J Gynecol Oncol 2002;7:140−2.6. Ray-Coquard I. Ovarian tumors of sex cord-stromal origin. Orphanet Encyclopedia. March 2004.Ray-Coquard I. Ovarian tumors of sex cord-stromal origin. Orphanet Encyclopedia. March 2004.7. Tavassoli Fattaneh A., Devilee P. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. I ARC Press. Lyon, 2003. Pp. 152−6.Tavassoli Fattaneh A., Devilee P. Pathology and Genetics of Tumours of the Breast and Female Genital Organs. I ARC Press. Lyon, 2003. Pp. 152−6.8. Choundhary S.V., Banode P.J., Bhake A. et al. Hirsutism with virilization in postmenopausal woman due to a rare ovarian steroid cell tumor. Indian Journal of Dermatology, Venerology and Leprology 2010;76(2):216.Choundhary S.V., Banode P.J., Bhake A. et al. Hirsutism with virilization in postmenopausal woman due to a rare ovarian steroid cell tumor. Indian Journal of Dermatology, Venerology and Leprology 2010;76(2):216.9. Grover V., Babu A. Hilar Leydig cell tumor presenting as hirsutism in a 51-year-old woman. Hospital Physician, 2007. Pp. 33−8.Grover V., Babu A. Hilar Leydig cell tumor presenting as hirsutism in a 51-year-old woman. Hospital Physician, 2007. Pp. 33−8.10. Nosov V., Park S., Rao J., Memarzadeh S. Non-Peutz-Jeghers syndrome associated ovarian sex cord tumor with annular tubules: a case report. Fertility and Sterility 2009; 92(4):1497.Nosov V., Park S., Rao J., Memarzadeh S. Non-Peutz-Jeghers syndrome associated ovarian sex cord tumor with annular tubules: a case report. Fertility and Sterility 2009; 92(4):1497.11. Roth L.M. Recent advances in the pathology and classification of ovarian sex cordystromal tumors. Int J Gynecol Pathol 2006;25(3):199−215.Roth L.M. Recent advances in the pathology and classification of ovarian sex cordystromal tumors. Int J Gynecol Pathol 2006;25(3):199−215.12. Young R.H., Welch W.R., Dickersin R., Scully R.E. Ovarian sex cord tumor with annular tubules. Review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix. Cancer 1982;50:1384−402.Young R.H., Welch W.R., Dickersin R., Scully R.E. Ovarian sex cord tumor with annular tubules. Review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix. Cancer 1982;50:1384−402.