Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press132810.17650/1994-4098-2024-20-4-139-147GYNECOLOGY. CLINICAL CASEГИНЕКОЛОГИЯ. КЛИНИЧЕСКИЙ СЛУЧАЙEmbryonic heritage: a unique case of Wolffian duct tumor in a 75-year-old female patient Modern approaches to morphological diagnosticsЭмбриональное наследие: уникальный случай опухоли из клеток вольфова протока у 75-летней пациентки. Современные подходы к морфологической диагностикеhttps://orcid.org/0000-0002-2773-1917VillertA. B.ВиллертА. Б.
Russian Federation

Alisa Borisovna Villert

5 Kooperativnyy Pereulok, Tomsk 634009, Russia 

 Алиса Борисовна Виллерт

 Россия, 634009 Томск, Кооперативный переулок, 5 

avillert@yandex.ruBondyrevaO. A.БондыреваО. А.
Russian Federation

5 Kooperativnyy Pereulok, Tomsk 634009, Russia

 Россия, 634009 Томск, Кооперативный переулок, 5 

https://orcid.org/0000-0002-1195-4008VtorushinS. V.ВторушинС. В.
Russian Federation

5 Kooperativnyy Pereulok, Tomsk 634009, Russia

2 Moskovskiy Trakt, Tomsk 634050, Russia 

Россия, 634009 Томск, Кооперативный переулок, 5 

Россия, 634009 Томск, ул. Московский тракт, 2 

https://orcid.org/0000-0002-6854-8940KolomietsL. A.КоломиецЛ. А.
Russian Federation

5 Kooperativnyy Pereulok, Tomsk 634009, Russia

2 Moskovskiy Trakt, Tomsk 634050, Russia 

Россия, 634009 Томск, Кооперативный переулок, 5 

Россия, 634009 Томск, ул. Московский тракт, 2 

https://orcid.org/0000-0001-6628-2918OchirovM. O.ОчировМ. О.
Russian Federation

 Россия, 634009 Томск, Кооперативный переулок, 5 

https://orcid.org/0000-0001-8212-731XMaltsevaA. A.МальцеваА. А.
Russian Federation

5 Kooperativnyy Pereulok, Tomsk 634009, Russia

 Россия, 634009 Томск, Кооперативный переулок, 5 

VillertS. A.ВиллертС. А.
Russian Federation

 2 Moskovskiy Trakt, Tomsk 634050, Russia 

Россия, 634009 Томск, ул. Московский тракт, 2 

Cancer Research Institute, Tomsk National Research Medical Center, Russian Academy of SciencesНаучно-исследовательский институт онкологии ФГБНУ «Томский национальный исследовательский медицинский центр РАН»Siberian State Medical University, Ministry of Health of RussiaФГБОУ ВО «Сибирский государственный медицинский университет» Минздрава России0312202420413914720102024030320252024https://ojrs.abvpress.ru/ojrs/article/view/1328

Female adnexal tumor of Wolffian origin is an extremely rare and poorly studied tumor arising from remnants of Wolffian (mesonephric) duct and having an ambiguous malignancy potential. Immunohistochemical diagnostics of these tumors is important to exclude other pathologies. Interpretation of the prognosis is ambiguous. There are no clear standards for surgical or chemotherapeutic treatment. This is due to the lack of a sufficient number of observations and clinical studies. The article presents a clinical case of Wolffian duct tumor diagnosed in a 75-year-old patient, with a discussion of the terminological, morphological, immunohistochemical and molecular genetic features of the tumor.

Опухоль из клеток вольфова (мезонефрального) протока – крайне редкое и малоизученное новообразование с неоднозначным потенциалом злокачественности. Иммуногистохимическая диагностика данных опухолей важна для исключения другой патологии. Интерпретация прогноза неоднозначна. четких стандартов хирургического или химиотерапевтического лечения не существует. Это связано с отсутствием достаточного количества наблюдений и клинических исследований. В статье представлено клиническое наблюдение опухоли из клеток вольфова протока, диагностированной у пациентки 75 лет, с обсуждением терминологических, морфологических, иммуногистохимических и молекулярно-генетических особенностей опухоли.

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