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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1385</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2025-21-2-135-144</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>GYNECOLOGY. CLINICAL CASE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ. КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Recurrence of borderline ovarian tumor during pregnancy – is wait-and-see approach a possible strategy? Case report and literature review</article-title><trans-title-group xml:lang="ru"><trans-title>Рецидив пограничной опухоли яичников во время беременности – оправданна ли выжидательная тактика? Клинический случай и обзор литературы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-5149-2885</contrib-id><name-alternatives><name xml:lang="en"><surname>Chekina</surname><given-names>Yu. A.</given-names></name><name xml:lang="ru"><surname>Чекина</surname><given-names>Ю. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Yuliya Andreevna Chekina</p><p>2 Akkuratova St., Saint Petersburg 197341</p></bio><bio xml:lang="ru"><p>Юлия Андреевна Чекина</p><p>197341 Санкт-Петербург, ул. Аккуратова, 2</p></bio><email>chekina.julia@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kalinina</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Калинина</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>2 Akkuratova St., Saint Petersburg 197341</p></bio><bio xml:lang="ru"><p>197341 Санкт-Петербург, ул. Аккуратова, 2</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Li</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Ли</surname><given-names>О. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>2 Akkuratova St., Saint Petersburg 197341</p></bio><bio xml:lang="ru"><p>197341 Санкт-Петербург, ул. Аккуратова, 2</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9656-1704</contrib-id><name-alternatives><name xml:lang="en"><surname>Koshevaya</surname><given-names>E. G.</given-names></name><name xml:lang="ru"><surname>Кошевая</surname><given-names>Е. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>2 Akkuratova St., Saint Petersburg 197341</p></bio><bio xml:lang="ru"><p>197341 Санкт-Петербург, ул. Аккуратова, 2</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2817-2977</contrib-id><name-alternatives><name xml:lang="en"><surname>Dzharbaeva</surname><given-names>A. D.</given-names></name><name xml:lang="ru"><surname>Джарбаева</surname><given-names>А. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>2 Akkuratova St., Saint Petersburg 197341</p></bio><bio xml:lang="ru"><p>197341 Санкт-Петербург, ул. Аккуратова, 2</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2835-2983</contrib-id><name-alternatives><name xml:lang="en"><surname>Dikareva</surname><given-names>E. L.</given-names></name><name xml:lang="ru"><surname>Дикарева</surname><given-names>Е. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>2 Akkuratova St., Saint Petersburg 197341</p></bio><bio xml:lang="ru"><p>197341 Санкт-Петербург, ул. Аккуратова, 2</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Urmancheeva</surname><given-names>A. F.</given-names></name><name xml:lang="ru"><surname>Урманчеева</surname><given-names>А. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p><p>41 Kirochnaya St., Saint Petersburg 191015</p></bio><bio xml:lang="ru"><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p><p>191015 Санкт-Петербург, ул. Кирочная, 41</p></bio><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2701-8812</contrib-id><name-alternatives><name xml:lang="en"><surname>Ulrikh</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Ульрих</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>2 Akkuratova St., Saint Petersburg 197341</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p><p>41 Kirochnaya St., Saint Petersburg 191015</p></bio><bio xml:lang="ru"><p>197341 Санкт-Петербург, ул. Аккуратова, 2</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p><p>191015 Санкт-Петербург, ул. Кирочная, 41</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">V.A. Almazov National Medical Research Center, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр им. В. А. Алмазова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н. Н. Петрова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И. И. Мечникова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2025-08-03" publication-format="electronic"><day>03</day><month>08</month><year>2025</year></pub-date><volume>21</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>135</fpage><lpage>144</lpage><history><date date-type="received" iso-8601-date="2025-08-03"><day>03</day><month>08</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-08-03"><day>03</day><month>08</month><year>2025</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/1385">https://ojrs.abvpress.ru/ojrs/article/view/1385</self-uri><abstract xml:lang="en"><p>Borderline ovarian tumors (BOT) are neoplasms with low malignant potential, which are characterized by atypical epithelial proliferation without destructive stromal invasion. They account for 15–20 % of all epithelial ovarian tumors, with serous and mucinous BOT being the most common. The incidence of BOT ranges from 1.5 to 4.8 cases per 100,000 women, with at least one-third of patients being younger than 40 years at the time of diagnosis. Therefore, one of the most critical aspects of treatment is fertility preservation. The “gold standard” for organ-sparing treatment is resection of the affected ovary or adnexectomy, accompanied by mandatory surgical staging. Most BOT are diagnosed at early stages (FIGO I), ensuring a favorable prognosis with a 5-year survival rate of 95 % and a 10-year survival rate of 90 %. Recurrences occur in 5–34 % of cases, most often as borderline tumors and less frequently as invasive ones. Although conservative treatment is considered one of the risk factors for subsequent recurrences, its impact on overall survival has not been proven. We describe a clinical case of fertility-sparing treatment for a recurrent during second pregnancy BOT, initially diagnosed in a young woman during the first trimester of her first pregnancy.</p></abstract><trans-abstract xml:lang="ru"><p>Пограничные опухоли яичников (ПОЯ) – новообразования с низким злокачественным потенциалом, которые характеризуются атипичной пролиферацией эпителия без деструктивной стромальной инвазии. Они составляют 15–20 % всех эпителиальных опухолей яичников, наиболее распространенными из них являются серозные и муцинозные ПОЯ. заболеваемость ПОЯ варьирует от 1,5 до 4,8 случая на 100 тыс. женщин, при этом как минимум треть из них на момент установления диагноза моложе 40 лет, поэтому один из важнейших аспектов лечения заключается в сохранении фертильности. «золотым стандартом» органосохраняющего лечения является резекция пораженного яичника или аднексэктомия с обязательным хирургическим стадированием. большинство ПОЯ диагностируются на ранних стадиях (I по FIGO), что обеспечивает благоприятный прогноз: 5-летняя выживаемость пациенток составляет 95 %, 10-летняя – 90 %. Рецидивы встречаются в 5–34 % случаев, чаще в форме пограничных опухолей, реже – инвазивных. Несмотря на то что консервативное лечение относится к одному из факторов риска развития последующих рецидивов, его влияние на снижение общей выживаемости доказано не было. Мы описываем клинический случай органосохраняющего лечения рецидивирующей серозной ПОЯ во время второй беременности, впервые выявленной у молодой девушки в I триместре ее первой беременности.</p></trans-abstract><kwd-group xml:lang="en"><kwd>borderline ovarian tumor</kwd><kwd>recurrence</kwd><kwd>fertility-sparing surgery</kwd><kwd>pregnancy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>пограничная опухоль яичников</kwd><kwd>рецидив</kwd><kwd>органосохраняющее лечение</kwd><kwd>беременность</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Kipp B., Vidal A., Lenick D., Christmann-Schmid C. Management of Borderline ovarian tumors (BOT): Results of a retrospective, single center study in Switzerland. J Ovarian Res 2023;16(1):20. 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