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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">15</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2014-0-1-74-77</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>GYNECOLOGY. DIAGNOSIS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ. ДИАГНОСТИКА</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Computer morphometry: experience in the study of clinical value in endometrial precancer</article-title><trans-title-group xml:lang="ru"><trans-title>Компьютерная морфометрия: опыт изучения клинической значимости при предраке эндометрия</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bishtavi</surname><given-names>A. Kh.</given-names></name><name xml:lang="ru"><surname>Биштави</surname><given-names>А. Х.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gornykh</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Горных</surname><given-names>О. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kanibolotsky</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Каниболоцкий</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tabakman</surname><given-names>Yu. Yu.</given-names></name><name xml:lang="ru"><surname>Табакман</surname><given-names>Ю. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>tabakman37@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Manukhin</surname><given-names>I. B.</given-names></name><name xml:lang="ru"><surname>Манухин</surname><given-names>И. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Department of Obstetrics and Gynecology, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Кафедра акушерства и гинекологии ГБОУ ВПО МГМСУ им. А.И. Евдокимова Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Department of Obstetrics and Gynecology, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia&#13;
Clinical Oncology Dispensary One, Moscow Healthcare Department</institution></aff><aff><institution xml:lang="ru">кафедра акушерства и гинекологии ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздава России&#13;
ГБУЗ «Онкологический клинический диспансер No 1» Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-07-17" publication-format="electronic"><day>17</day><month>07</month><year>2014</year></pub-date><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>74</fpage><lpage>77</lpage><history><date date-type="received" iso-8601-date="2014-07-17"><day>17</day><month>07</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-07-17"><day>17</day><month>07</month><year>2014</year></date></history><permissions/><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/15">https://ojrs.abvpress.ru/ojrs/article/view/15</self-uri><abstract xml:lang="en"><p>The differential diagnosis of simple endometrial hyperplasia (SEH), complex endometrial hyperplasia (CEH), atypical endometrial hyper- plasia (AEH), and endometrial cancer (EC) is associated with a number of difficulties, frequently giving rise to different interpretations of the same histology specimens.<bold>Objective</bold>: to assess the possibilities of computed morphometry in endometrial hyperplasia.<bold>Subjects and methods</bold>. The investigation included 35 patients, including 12 with SEH, 11 with CEH, 7 with AEH, and 5 with EC. Endome- trial computed morphometry was performed using the ImageScope Color.<bold>Conclusion</bold>. The morphometric changes in endometrial hyperplasia, which are expressed in quantitative indicators, are much more diverse than their schematic image in the current classification, which may be a reason for a difference between the diagnoses.</p></abstract><trans-abstract xml:lang="ru"><p>Дифференциальная диагностика простой гиперплазии эндометрия (ПГЭ), сложной гиперплазии эндометрия (СГЭ), атипической гиперплазии эндометрия (АГЭ) и рака эндометрия (РЭ) сопряжена с рядом трудностей, что нередко приводит к различной трак- товке одних и тех же гистологических препаратов.<bold>Цель исследования</bold> – оценить возможности компьютерной морфометрии при гиперплазии эндометрия.<bold>Материалы и методы</bold>. В исследование включены 35 больных, из них ПГЭ наблюдалась у 12 человек, СГЭ – у 11, АГЭ – у 7, РЭ – у 5. Компьютерную морфометрию эндометрия проводили с использованием программы ImageScope Color.<bold>Заключение</bold>. Морфометрические изменения при гиперплазии эндометрия, выраженные в количественных параметрах, значитель- но многообразнее, чем их схематическое определение в современной классификации, что, возможно, является причиной расхо- ждений диагнозов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>endometrial hyperplasia</kwd><kwd>endometrial intraepithelial neoplasia</kwd><kwd>computer morphometry</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гиперплазия эндометрия</kwd><kwd>эндометриальная интраэпителиальная неоплазия</kwd><kwd>компьютерная морфометрия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Чепик О.Ф. 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