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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">196</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2011-0-4-46-53</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>PHARMACOTHERAPY</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ. ФАРМАКОТЕРАПИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Drug treatment for metastatic breast cancer</article-title><trans-title-group xml:lang="ru"><trans-title>Лекарственное лечение метастатического рака молочной железы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Artamonova</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Артамонова</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>artamonovae@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow</institution></aff><aff><institution xml:lang="ru">ФГБУ РОНЦ им. Н.Н. Блохина РАМН, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-11-18" publication-format="electronic"><day>18</day><month>11</month><year>2011</year></pub-date><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>46</fpage><lpage>53</lpage><history><date date-type="received" iso-8601-date="2014-08-21"><day>21</day><month>08</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-08-21"><day>21</day><month>08</month><year>2014</year></date></history><permissions><copyright-year>2011</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/196">https://ojrs.abvpress.ru/ojrs/article/view/196</self-uri><abstract xml:lang="en"><p>The paper describes the basic principles of drug therapy for metastatic breast cancer and considers treatment options for this disease. It also analyzes and details hormonal therapy and chemotherapy regimens and evaluates the efficacy of drugs used in these regimens and their dif- ferent combinations.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлены основные принципы лекарственной терапии метастатического рака молочной железы, рассмотрены варианты лечения этого заболевания. Проанализированы и подробно описаны режимы гормоно- и химиотерапии, дана оценка эффективности препаратов, применяемых в этих режимах, и различных их комбинаций.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>метастатический рак молочной железы</kwd><kwd>лекарственное лечение</kwd><kwd>гормональная терапия</kwd><kwd>химиотерапия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Saad E., Katz A., Machado K., Buyse M. 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