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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">199</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2011-0-4-59-63</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>GYNECOLOGY. PROBLEM</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ. ПРОБЛЕМА</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Hyperplasia and endometrial precancer</article-title><trans-title-group xml:lang="ru"><trans-title>Гиперплазия и предрак эндометрия</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gornikh</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Горных</surname><given-names>О. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Samoilenko</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Самойленко</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bishtavi</surname><given-names>A. K.</given-names></name><name xml:lang="ru"><surname>Биштави</surname><given-names>А. Х.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>haled72@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kanibolotsky</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Каниболоцкий</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Manukhin</surname><given-names>I. B.</given-names></name><name xml:lang="ru"><surname>Манухин</surname><given-names>И. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tabakman</surname><given-names>U. U.</given-names></name><name xml:lang="ru"><surname>Табакман</surname><given-names>Ю. Ю.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Department of Obstetrics and Gynecology MGMSU</institution></aff><aff><institution xml:lang="ru">Кафедра акушерства и гинекологии МГМСУ</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Cancer Clinic No 1 Department of Health in Moscow</institution></aff><aff><institution xml:lang="ru">Онкологический клинический диспансер No 1 Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-11-18" publication-format="electronic"><day>18</day><month>11</month><year>2011</year></pub-date><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>59</fpage><lpage>63</lpage><history><date date-type="received" iso-8601-date="2014-08-21"><day>21</day><month>08</month><year>2014</year></date></history><permissions><copyright-year>2011</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/199">https://ojrs.abvpress.ru/ojrs/article/view/199</self-uri><abstract xml:lang="en"><p>Hyperplastic process is nothing but excessive proliferation determining by histological or cytological method. Extending of theprecancer" conception including not only atypical endometrial hyperplasia but also other pathological changes of the endometriu m (glandu- lar-cystic hyperplasia, polyposis), with the marked endocrine and metabolic disorders background is of some scientific interest and encour- ages a search for a wide range of hypothetical pathogenetic mechanisms and w ays to prevent precancer and endometrial cancer . However, such an extension of the view on the endometrial precancer is not an equivalent of the nosological diagnosis which involves anexact morpho- logic substrate of the pathological process and a specific treatment policy.</p></abstract><trans-abstract xml:lang="ru"><p>Расширение понятия «предрак эндометрия» с включением в него, помимо атипической гиперплазии эндометрия, также и других патологических изменений эндометрия (железисто-кистозная гиперплазия, полипоз), возникающих на фоне выраженных эндокринно-обменных нарушений, представляет определенный научный интерес. Однако такое расширение представления о предраке эндометрия не может быть эквивалентом нозологического диагноза, который предполагает четко определенный морфологический субстрат патологического процесса и конкретную лечебную тактику.</p></trans-abstract><kwd-group xml:lang="en"><kwd>endometrial hyperplasia</kwd><kwd>diagnostic</kwd><kwd>treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>гиперплазия эндометрия</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Sivridios E., Giatromanolaki A. The endometrial hyperplasias revisited. Virch Arch 2008;453:223–31.</mixed-citation><mixed-citation xml:lang="ru">Sivridios E., Giatromanolaki A. The endometrial hyperplasias revisited. 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