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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">204</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2011-0-4-84-86</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>GYNECOLOGY. DIAGNOSIS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ. ДИАГНОСТИКА</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">New verification possibilities for ovarian malignancies</article-title><trans-title-group xml:lang="ru"><trans-title>Новые возможности верификации злокачественных опухолей яичника</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Protasova</surname><given-names>A. E.</given-names></name><name xml:lang="ru"><surname>Протасова</surname><given-names>А. Э.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>Protasova1966@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Orlova</surname><given-names>R. V.</given-names></name><name xml:lang="ru"><surname>Орлова</surname><given-names>Р. В.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Raskin</surname><given-names>G. A.</given-names></name><name xml:lang="ru"><surname>Раскин</surname><given-names>Г. А.</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Department of Oncology, Moscow Academy of Postgraduate Education</institution></aff><aff><institution xml:lang="ru">Кафедра онкологии МАПО</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Medical Faculty, State University</institution></aff><aff><institution xml:lang="ru">медицинский факультет Государственного университета</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">City Clinical Oncology Dispensary, Saint Petersburg</institution></aff><aff><institution xml:lang="ru">Городской клинический онкологический диспансер, Санкт-Петербург</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2011-11-18" publication-format="electronic"><day>18</day><month>11</month><year>2011</year></pub-date><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>84</fpage><lpage>86</lpage><history><date date-type="received" iso-8601-date="2014-08-21"><day>21</day><month>08</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-08-21"><day>21</day><month>08</month><year>2014</year></date></history><permissions><copyright-year>2011</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/204">https://ojrs.abvpress.ru/ojrs/article/view/204</self-uri><abstract xml:lang="en"><p>The fact that the diagnosis can be significantly verified using the liquid-based cytology technique and immunocytochemical assain analyzed 72 cases with the ascites forms of ovarian cancer. The effective panel to diagnose ovarian adenocarcinomas with ascites may be considered as follows: Ber-EP4, calretinin for the differential diagnosis of the tumor with reactive changes, as well as estrog en receptors, WT-1, CK7 for the clarification of the type of adenocarcinoma (in case of a positive reaction to Ber-EP4). Verification of the mucinous form of adenocarcinoma is now made difficult by a negative reaction to organ-specific markers.</p></abstract><trans-abstract xml:lang="ru"><p>При асцитных формах рака яичника на проанализированных 72 случаях показана возможность достоверно верифицировать диагноз с помощью метода жидкостной цитологии и иммуноцитохимического исследования. Эффективной панелью для диагностики аденокарцином яичника c асцитом можно считать следующую: Ber-EP4, калретинин — с целью дифференциальной диагностики опухоли с реактивными изменениями и эстрогеновые рецепторы, WT-1, CK7 — для уточнения типа аденокарциномы (в случаепозитивной реакции на Ber-EP4). Верификация муцинозного типа аденокарциномы в настоящее время затруднена вследствие негативной реакции на органоспецифические маркеры.</p></trans-abstract><kwd-group xml:lang="en"><kwd>liquid-based cytology</kwd><kwd>immunocytochemical assay</kwd><kwd>ascites</kwd><kwd>ovarian cancer</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>жидкостная цитология</kwd><kwd>иммуноцитохимическое исследование</kwd><kwd>асцит</kwd><kwd>рак яичника</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Мерабишвили В.М., Щербук Ю.А. Онкологическая служба в Санкт-Петербурге и районах города в 2009 году (заболеваемость, смертность, выживаемость). СПб., 2010.</mixed-citation><mixed-citation xml:lang="ru">Мерабишвили В.М., Щербук Ю.А. Онкологическая служба в Санкт-Петербурге и районах города в 2009 году (заболеваемость, смертность, выживаемость). 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