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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">223</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2010-0-2-10-20</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>MAMMOLOGY. PROBLEM</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>МАММОЛОГИЯ. ПРОБЛЕМА</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Intervention treatments for chronic pain syndrome in cancer patients</article-title><trans-title-group xml:lang="ru"><trans-title>Интервенционные методы лечения хронического болевого синдрома у онкологических больных</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bryuzgin</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Брюзгин</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>bruzgin@ronc.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow</institution></aff><aff><institution xml:lang="ru">ГУ РОНЦ им. Н.Н. Блохина РАМН, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2010-05-27" publication-format="electronic"><day>27</day><month>05</month><year>2010</year></pub-date><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>10</fpage><lpage>20</lpage><history><date date-type="received" iso-8601-date="2014-08-27"><day>27</day><month>08</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-08-27"><day>27</day><month>08</month><year>2014</year></date></history><permissions><copyright-year>2010</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/223">https://ojrs.abvpress.ru/ojrs/article/view/223</self-uri><abstract xml:lang="en"><p>Noninvasive treatments for chronic pain syndrome benefit in 80-90% of cancer patients. Invasive, intervention procedures for analgesia should be used in other cases. These include neuroablative and neuromodulatory measures. Neuroablation is defined as the physical suspension of painful impulse transmission pathways by a surgical, chemical, or thermal method and comprises lytic and other blocks. Neuromodulation is the dynamic and functional suppression of pain impulse pathways by the intraspinal or intraventricular administra- tion of opioids and other chemicals.</p></abstract><trans-abstract xml:lang="ru"><p>Применение неинвазивных методик лечения хронического болевого синдрома у онкологических больных дает эффект у 80–90% больных. В остальных случаях следует использовать инвазивные, интервенционные методики обезболивания. К их числу относятся нейроаблативные и нейромодулирующие процедуры. Нейроаблация определяется как физическое прерывание путей передачи болевой импульсации хирургическим, химическим или термальным методом и включает в себя литические и другого рода блокады. Нейромодуляция - это динамическое и функциональное подавление путей передачи болевой импульсации в результате интраспинального или интравентрикулярного введения опиоидов и других химических агентов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>oncology</kwd><kwd>pain</kwd><kwd>analgesia</kwd><kwd>intervention procedures</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>онкология</kwd><kwd>боль</kwd><kwd>обезболивание</kwd><kwd>интервенционные методики</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Wang J.K., Nauss L.A., Thomas J.E. Pain relief by intrathecally applied morphine in man. Anesthesiology 1979;50:149–51.</mixed-citation><mixed-citation xml:lang="ru">Wang J.K., Nauss L.A., Thomas J.E. Pain relief by intrathecally applied morphine in man. 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