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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">261</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2010-0-4-6-10</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>MAMMOLOGY. TREATMENT</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>МАММОЛОГИЯ. ЛЕЧЕНИЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Comparative analysis of the long-term results of treatment in patients with Stages I-IIa breast cancer in relation to major prognostic factors</article-title><trans-title-group xml:lang="ru"><trans-title>Сравнительный анализ отдаленных результатов лечения больных раком молочной железы I–IIа стадий в зависимости от основных прогностических факторов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Efimkina</surname><given-names>Yu. V.</given-names></name><name xml:lang="ru"><surname>Ефимкина</surname><given-names>Ю. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>0152@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gladilina</surname><given-names>I. A.</given-names></name><name xml:lang="ru"><surname>Гладилина</surname><given-names>И. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shabanov</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Шабанов</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nechushkin</surname><given-names>M. I.</given-names></name><name xml:lang="ru"><surname>Нечушкин</surname><given-names>М. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Uimanov</surname><given-names>V. A.</given-names></name><name xml:lang="ru"><surname>Уйманов</surname><given-names>В. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Department of Radiosurgery, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow</institution></aff><aff><institution xml:lang="ru">Отделение радиохирургии ГУ РОНЦ им. Н.Н. Блохина РАМН, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2010-11-29" publication-format="electronic"><day>29</day><month>11</month><year>2010</year></pub-date><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>6</fpage><lpage>10</lpage><history><date date-type="received" iso-8601-date="2014-08-29"><day>29</day><month>08</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-08-29"><day>29</day><month>08</month><year>2014</year></date></history><permissions><copyright-year>2010</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/261">https://ojrs.abvpress.ru/ojrs/article/view/261</self-uri><abstract xml:lang="en"><p>The analysis of the long-term results of treatment in patients with Stages I-IIa breast cancer in relation to major prognostic factors re- vealed poor morphological factors that greatly influenced the lifespan of female patients, such as tumor invasion along the neural fibers, tumor necrosis, cancer emboli in the lymph gaps and vessels, vascular tumor invasion.</p></abstract><trans-abstract xml:lang="ru"><p>При анализе отдаленных результатов лечения больных раком молочной железы I–IIа стадий в зависимости от основных прогностических факторов были выявлены неблагоприятные морфологические, достоверно влияющие на продолжительность жизни пациенток факторы: наличие опухолевой инвазии по невральным волокнам, некроз опухоли, раковые эмболы в лимфатических щелях и сосудах, сосудистая опухолевая инвазия.</p></trans-abstract><kwd-group xml:lang="en"><kwd>lbreast cancer</kwd><kwd>organ-saving treatment</kwd><kwd>radiotherapy</kwd><kwd>prognostic factors</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>органосохраняющее лечение</kwd><kwd>лучевая терапия</kwd><kwd>прогностические факторы</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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