Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press26310.17650/1994-4098-2010-0-4-15-23MAMMOLOGY. TREATMENTМАММОЛОГИЯ. ЛЕЧЕНИЕTaxanes in adjuvant and neoadjuvant therapy for breast cancerТаксаны в адъювантной и неоадъювантной терапии рака молочной железыLimarevaS. V.ЛимареваС. В.
Russian Federation
s-limareva@yandex.ruDepartment of Chemotherapy, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowОтделение химиотерапии ГУ РОНЦ им. Н.Н. Блохина РАМН, Москва291120104152329082014290820142010https://ojrs.abvpress.ru/ojrs/article/view/263

Taxanes (paclitaxel and docetaxel) are currently considered to be basic cytostatics in the treatment of all breast cancer (BC) stages. The results of conducted and ongoing clinical trials suggest that incorporation of taxanes into adjuvant and neoadjuvant chemotherapy regimens enhances the efficiency of treatment for operable BC and show it necessary to apply an individual approach depending on prognostic and predictive factors.

В настоящее время таксаны (паклитаксел и доцетаксел) являются базовыми цитостатиками, применяющимися в лечении всех стадий рака молочной железы (РМЖ). Результаты проведенных и продолжающихся в настоящее время клинических исследований свидетельствуют о повышении эффективности лечения операбельного РМЖ при включении таксанов в режимы адъювантной и неоадъювантной химиотерапии и указывают на необходимость использования индивидуального подхода в зависимости от прогностических и предикторных факторов.

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