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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">306</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2009-0-3-4-11-14</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>MAMMOLOGY. TOPICAL ISSUE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>МАММОЛОГИЯ. АКТУАЛЬНАЯ ТЕМА</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">ROLE OF PROGNOSTIC FACTORS IN THE DEVELOPMENT OF CENTRIC BREAST CANCER RECURRENCE</article-title><trans-title-group xml:lang="ru"><trans-title>РОЛЬ ПРОГНОСТИЧЕСКИХ ФАКТОРОВ В РАЗВИТИИ РЕЦИДИВА РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ ЦЕНТРАЛЬНОЙ ЛОКАЛИЗАЦИИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sotskova</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Соцкова</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>azizz@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Petrovsky</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Петровский</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Poddubnaya</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Поддубная</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nechushkin</surname><given-names>M. I.</given-names></name><name xml:lang="ru"><surname>Нечушкин</surname><given-names>М. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Cancer, Russian Academy of Medical Sciences, Moscow</institution></aff><aff><institution xml:lang="ru">ГУ РОНЦ им. Н.Н. Блохина РАМН, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2009-11-10" publication-format="electronic"><day>10</day><month>11</month><year>2009</year></pub-date><issue>3-4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>11</fpage><lpage>14</lpage><history><date date-type="received" iso-8601-date="2014-09-10"><day>10</day><month>09</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-09-10"><day>10</day><month>09</month><year>2014</year></date></history><permissions><copyright-year>2009</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/306">https://ojrs.abvpress.ru/ojrs/article/view/306</self-uri><abstract xml:lang="en"><p>The purpose of the study was to define the factors influencing the development of a recurrence depending on the volume of surgical intervention and to investigate the possibility of performing organ-saving surgery (OSS) for centric breast cancer.The study used the clinical findings of 200 patients treated at the Department of Radiosurgery, N.N. Blokhin Russian Cancer Research Center in 1996 to 2006. According to the volume of surgical intervention, the patients were divided into 2 groups: 1) 106 patients who had undergone radical mastectomy; 2) 94 patients who had undergone radical resection. According to our data, the disease progressed in 32 (16%) cases. There were 12 local recurrences: in 8 (7.5%) and 4 (4.2%) cases after radical mastectomy and radical resection, respec- tively. The findings suggest that OSS may be performed after carefully patient selection, with all contraindications being kept in mind.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель исследования</bold> — определение факторов, влияющих на развитие рецидива в зависимости от объема оперативного вмешательства, и возможности выполнения органосохраняющей операции (ОСО) при раке молочной железы центральной локализации.В работе использованы материалы клинического наблюдения 200 больных, получивших лечение в отделении радиохирургии ГУ РОНЦ им. Н.Н. Блохина РАМН в период с 1996 по 2006 г. Пациентки были разделены на 2 группы в зависимости от объема операции. В 1-ю груп- пу включены 106 больных, которым проведена операция в объеме радикальной мастэктомии, во 2-ю — 94 пациентки, подвергшиеся ради- кальной резекции. По нашим данным, прогрессирование болезни развилось в 32 (16%) наблюдениях. Локальных рецидивов было 12: после ра- дикальной мастэктомии в 8 (7,5%) случаях, после радикальной резекции — в 4 (4,2%). Полученные результаты свидетельствуют о воз- можности выполнения ОСО при тщательном отборе пациентов с учетом всех противопоказаний.</p></trans-abstract><kwd-group xml:lang="en"><kwd>centric breast cancer</kwd><kwd>development of a recurrence</kwd><kwd>organ-saving operations</kwd><kwd>prognostic factors</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ак молочной железы центральной локализации</kwd><kwd>развитие рецидива</kwd><kwd>органосохраняющие операции</kwd><kwd>прогностические факторы</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Вишнякова В.В. Эффективность экономных операций при раке молочной железы. Вопр онкол 1990;36(5):540—4.</mixed-citation><mixed-citation xml:lang="ru">Вишнякова В.В. Эффективность экономных операций при раке молочной железы. Вопр онкол 1990;36(5):540—4.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Летягин В.П. Современные тенденции в лечении первичного рака молочной железы. Вестн ВОНЦ АМН СССР 1990;(1):40—2.</mixed-citation><mixed-citation xml:lang="ru">Летягин В.П. Современные тенденции в лечении первичного рака молочной железы. Вестн ВОНЦ АМН СССР 1990;(1):40—2.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Портной С.М., Лактионов К.П., Барканов А.И. и др. Органосохраняющие операции при раке молочной железы I—II стадии. Материалы I съезда онкологов стран СНГ. М., 1996.</mixed-citation><mixed-citation xml:lang="ru">Портной С.М., Лактионов К.П., Барканов А.И. и др. Органосохраняющие операции при раке молочной железы I—II стадии. Материалы I съезда онкологов стран СНГ. М., 1996.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Семиглазов В.Ф., Веснин А.Г., Мо- исеенко В.М. Минимальный рак молочной железы. Спб.: Гиппократ, 1992.</mixed-citation><mixed-citation xml:lang="ru">Семиглазов В.Ф., Веснин А.Г., Мо- исеенко В.М. Минимальный рак молочной железы. Спб.: Гиппократ, 1992.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Fisher B., Slack N.H., Cavanaugh P.J. Postoperative radiotherapy in the treatment of breast cancer: results of the NSABP clin- ical trial. Ann Surg 1970;172(4):711—32.</mixed-citation><mixed-citation xml:lang="ru">Fisher B., Slack N.H., Cavanaugh P.J. Postoperative radiotherapy in the treatment of breast cancer: results of the NSABP clin- ical trial. Ann Surg 1970;172(4):711—32.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Veronesi U., Luini A., Del Vecchio M. et al. Radiotherapy after breast-preserv- ing surgery in woman with localized can- cer of the breast. N Engl J Med 1993;328:1587—91.</mixed-citation><mixed-citation xml:lang="ru">Veronesi U., Luini A., Del Vecchio M. et al. Radiotherapy after breast-preserv- ing surgery in woman with localized can- cer of the breast. N Engl J Med 1993;328:1587—91.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Путырский Л.А. Рак молочной железы. Минск, 1998.</mixed-citation><mixed-citation xml:lang="ru">Путырский Л.А. Рак молочной железы. Минск, 1998.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Rutgers E.J.Th. for the EUSOMA Consensus Group. Qualiti assurance guidelines for surgery. European guide- lines for guality assurance in breast can- cer screening and diagnosis, 2006.</mixed-citation><mixed-citation xml:lang="ru">Rutgers E.J.Th. for the EUSOMA Consensus Group. Qualiti assurance guidelines for surgery. European guide- lines for guality assurance in breast can- cer screening and diagnosis, 2006.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9. Goldhirsch A., Wood W., Gelber R. et al. Progress and promis: highlights of the international expert consensus on the pri- mari therapy of early breast cancer 2007. Ann Oncol 2007;18(7):1133—44.</mixed-citation><mixed-citation xml:lang="ru">Goldhirsch A., Wood W., Gelber R. et al. Progress and promis: highlights of the international expert consensus on the pri- mari therapy of early breast cancer 2007. Ann Oncol 2007;18(7):1133—44.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10. Fowble B.L., Solin L.J., Schultz D.J. Breast recurrence and survival related to primary tumor location in patients under- going conservative surgery and radiation for early stage breast cancer. Int J Radiat Oncol Biol Phys 1992;23(5):933—9.</mixed-citation><mixed-citation xml:lang="ru">Fowble B.L., Solin L.J., Schultz D.J. Breast recurrence and survival related to primary tumor location in patients under- going conservative surgery and radiation for early stage breast cancer. Int J Radiat Oncol Biol Phys 1992;23(5):933—9.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
