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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">309</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2009-0-3-4-25-28</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>MAMMOLOGY. DIAGNOSIS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>МАММОЛОГИЯ. ДИАГНОСТИКА</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">MOLECULAR BIOLOGICAL AND RADIOLOGICAL TECHNOLOGIES IN THE COMPLEX DIAGNOSIS OF AUXILLARY PATHOLOGY</article-title><trans-title-group xml:lang="ru"><trans-title>МОЛЕКУЛЯРНО-БИОЛОГИЧЕСКИЕ И РАДИОЛОГИЧЕСКИЕ ТЕХНОЛОГИИ В КОМПЛЕКСНОЙ ДИАГНОСТИКЕ ПАТОЛОГИИ АКСИЛЛЯРНОЙ ОБЛАСТИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rozhkova</surname><given-names>N. I.</given-names></name><name xml:lang="ru"><surname>Рожкова</surname><given-names>Н. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bozhenko</surname><given-names>V. K.</given-names></name><name xml:lang="ru"><surname>Боженко</surname><given-names>В. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>vbojenko@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Fomin</surname><given-names>D. K.</given-names></name><name xml:lang="ru"><surname>Фомин</surname><given-names>Д. К.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ploshnitsa</surname><given-names>A. I.</given-names></name><name xml:lang="ru"><surname>Плошница</surname><given-names>А. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tashchan</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Тащан</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kudinova</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Кудинова</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vaskevich</surname><given-names>E. F.</given-names></name><name xml:lang="ru"><surname>Васкевич</surname><given-names>Е. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mazo</surname><given-names>M. L.</given-names></name><name xml:lang="ru"><surname>Мазо</surname><given-names>М. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Russian Radiology Research Center, Moscow</institution></aff><aff><institution xml:lang="ru">ФГУ РНЦР, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2009-11-10" publication-format="electronic"><day>10</day><month>11</month><year>2009</year></pub-date><issue>3-4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>25</fpage><lpage>28</lpage><history><date date-type="received" iso-8601-date="2014-09-10"><day>10</day><month>09</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-09-10"><day>10</day><month>09</month><year>2014</year></date></history><permissions><copyright-year>2009</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/309">https://ojrs.abvpress.ru/ojrs/article/view/309</self-uri><abstract xml:lang="en"><p><bold>Introduction</bold>. A diversity of axillary pathologies was a prerequisite for the development of a new differential approach to diagnosing such conditions. There are new technologies (pre- and intraoperative radionuclide studies, molecular genetic techniques), that have shown themselves, along with classical methods (physical examination, mammography, X-ray and ultrasound studies).<bold>Materials and methods</bold>. The subject of the analysis is the results of a comprehensive examination of 502 women aged 22 to 84 years. Different groups were comprehensively examined using both X-ray, ultrasound, radionuclide, and molecular genetic (polymerase chain reaction) studies.<bold>Results</bold>. The molecular genetic and cytological studies could provide the actual results in 95 and 84% of cases, respectively; but a com- prehensive clinical study and X-ray ultrasound computed tomography could yield them in marginal metastases in only 65.3%. <bold>Conclusion</bold>. The authors have proposed the optimal diagnostic algorithm for examination in the ambulatory-outpatient network and specialized institutions.</p></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>auxillary diseases</kwd><kwd>diagnosis</kwd><kwd>radiological and molecular genetic studies</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>заболевания аксиллярной области</kwd><kwd>диагностика</kwd><kwd>радиологические и молекулярно-генетические методы</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Fisher B., Osborn K., Margolese R. et al. Neoplasms of the breast. In: Cancer medicine. 3d ed. Eds. J. Holland et al. Baltimore, 1993. p. 1706—74.</mixed-citation><mixed-citation xml:lang="ru">Fisher B., Osborn K., Margolese R. et al. Neoplasms of the breast. In: Cancer medicine. 3d ed. Eds. J. Holland et al. 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