Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press33410.17650/1994-4098-2008-0-1-28-32MAMMOLOGY. NEW TECHNOLOGIESМАММОЛОГИЯ. НОВЫЕ ТЕХНОЛОГИИCLINICAL SIGNIFICANCE OF THE VEGFR-2 IN THE TUMORS AND BLOOD SERA OF THE BREAST CANCER PATIENTSКЛИНИЧЕСКОЕ ЗНАЧЕНИЕ VEGFR-2 В ОПУХОЛЯХ И СЫВОРОТКАХ КРОВИ БОЛЬНЫХ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫKimE. A.КимЕ. А.
Russian Federation
PlatovaA. M.ПлатоваА. М.
Russian Federation
VisotzkayaI. V.ВысоцкаяИ. В.
Russian Federation
GershteynE. S.ГерштейнЕ. С.
Russian Federation
LetyaginV. P.ЛетягинВ. П.
Russian Federation
KushlinskiyN. E.КушлинскийН. Е.
Russian Federation
MironovaE. E.МироноваЕ. Е.
Russian Federation
I.M. Sechenov Moscow Medical AcademyММА им. И.М. СеченоваScientific and Research Institute of Clinical Oncology of N.N. Blokhin Cancer Research Center of Russian Academy of Medical SciencesНИИ клинической онкологии РОНЦ им. Н.Н. Блохина РАМН, Москва150220081283215092014150920142008https://ojrs.abvpress.ru/ojrs/article/view/334

The analysis of the changes of the content of the angiogenic factor VEGFR-2 in the cytosol of the tumor and blood sera of the 30 breast can- cer patients determined by immunoenzyme method during neoadjuvant therapy is given. Likewise the correlation of this index with the main clinicomorphological characteristics of the disease is assessed. The obtained results suggest on the possibility of the use of VEGFR-2 as the one of the diagnostic markers of the breast cancer. The index dynamics didn’t depend on the given therapy type but nonetheless the correlation of the VEGFR-2 content in the residual tumor after preoperative therapy with the grade of the treatment pathomorphosis is determined.

КЛИНИЧЕСКОЕ ЗНАЧЕНИЕ VEGFR-2 В ОПУХОЛЯХ И СЫВОРОТКАХ КРОВИ БОЛЬНЫХ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ

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