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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">346</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2008-0-2-27-32</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>MAMMOLOGY. TREATMENT</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>МАММОЛОГИЯ. ЛЕЧЕНИЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">CONTEMPORARY TRENDS IN THE TREATMENT OF METASTATIC BREAST CANCER</article-title><trans-title-group xml:lang="ru"><trans-title>СОВРЕМЕННЫЕ ТЕНДЕНЦИИ В ЛЕЧЕНИИ МЕТАСТАТИЧЕСКОГО РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Borisov</surname><given-names>V. I.</given-names></name><name xml:lang="ru"><surname>Борисов</surname><given-names>В. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Oncologic clinical dispensary No1, Moscow</institution></aff><aff><institution xml:lang="ru">Онкологический клинический диспансер No1, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2008-05-16" publication-format="electronic"><day>16</day><month>05</month><year>2008</year></pub-date><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>27</fpage><lpage>32</lpage><history><date date-type="received" iso-8601-date="2014-09-16"><day>16</day><month>09</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-09-16"><day>16</day><month>09</month><year>2014</year></date></history><permissions><copyright-year>2008</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/346">https://ojrs.abvpress.ru/ojrs/article/view/346</self-uri><abstract xml:lang="en"><p>Contemporary trends in the treatment of metastatic breast cancer are reviewed in the article: among them is so called targeted ther- apy. The main distinction of the targeted therapy is the maximum effect on tumor cell, at the same time minimum influence on nor- mal tissues is exerted. The author describes conservative approaches to the treatment of patients with metastatic breast cancer, the most effective schemes of drug therapy and basic prognostic factors affecting the choice of treatment tactics of patients with metasta- tic breast cancer. Besides, the randomized clinical trials addressing the current trends in the treatment of metatstatic breast cancer are evaluated.</p></abstract><trans-abstract xml:lang="ru"><p>СОВРЕМЕННЫЕ ТЕНДЕНЦИИ В ЛЕЧЕНИИ МЕТАСТАТИЧЕСКОГО РАКА МОЛОЧНОЙ ЖЕЛЕЗЫ</p></trans-abstract><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Гарин А.М. Молекулярные мишени современной лекарственной терапии опухолей. ХI Российский онкологический конгресс. 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