Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press38210.17650/1994-4098-2008-0-4-52-56GYNECOLOGY. TOPICAL SUBJECTГИНЕКОЛОГИЯ. АКТУАЛЬНАЯ ТЕМАBREAST CANCER AND IN VITRO FERTILIZATION PROGRAMРАК МОЛОЧНОЙ ЖЕЛЕЗЫ И ПРОГРАММА ЭКСТРАКОРПОРАЛЬНОГО ОПЛОДОТВОРЕНИЯParokonnayaA. A.ПароконнаяА. А.
Russian Federation
NechushkinM. I.НечушкинМ. И.
Russian Federation
Kampova-PolevayaYe. B.Кампова-ПолеваяЕ. Б.
Russian Federation
LyubchenkoL. N.ЛюбченкоЛ. Н.
Russian Federation
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical SciencesГУ РОНЦ им. Н.Н. Блохина РАМН, Москва171120084525617092014170920142008https://ojrs.abvpress.ru/ojrs/article/view/382

Eleven cases of breast cancer (BC) diagnosed during or after in-vitro fertilization (IVF) are considered. The study group was observed to have cases of familial BC in 18.2% of the patients and BRCA1 gene mutations in 60%. At the same time 45.5% of cases had local- ly advanced and generalized BC, which suggests that there is a tumor at the initiation of a regular IVF cycle. The authors arrive at the conclusion that it is necessary to include a mammologist's examination, breast ultrasonography, and an oncogeneticist's counseling into the package of compulsory measures during IVF.

РАК МОЛОЧНОЙ ЖЕЛЕЗЫ И ПРОГРАММА ЭКСТРАКОРПОРАЛЬНОГО ОПЛОДОТВОРЕНИЯ

1. Ayhan A., Salman C.A., Celik H. et al. Association between fertility drugs and gynecologic cancers, breast cancer, and childhood cancers. Acta Obstetricia et Gynecologica Scandinavica 2004;83(12). 2. Braga C., Negri E., La Vecchia C. et al. Fertility treatment and risk of breast can- cer. Hum Reprod 1996;11:300—3.Ayhan A., Salman C.A., Celik H. et al. Association between fertility drugs and gynecologic cancers, breast cancer, and childhood cancers. Acta Obstetricia et Gynecologica Scandinavica 2004;83(12). 2. Braga C., Negri E., La Vecchia C. et al. Fertility treatment and risk of breast can- cer. Hum Reprod 1996;11:300—3.3. Dor J., Lerner-Geva L., Rabinovici J. et al. Cancer incidence in a cohort of infertile women who underwent in vitro fertilization. Fertil Steril 2002;77:324—7. 4. Doyle P., Maconochie N., Beral V. Cancer incidence following treatment for infertility at a clinic in the UK. Hum Reprod 2002;17(8):2209—13.Dor J., Lerner-Geva L., Rabinovici J. et al. Cancer incidence in a cohort of infertile women who underwent in vitro fertilization. Fertil Steril 2002;77:324—7. 4. Doyle P., Maconochie N., Beral V. Cancer incidence following treatment for infertility at a clinic in the UK. Hum Reprod 2002;17(8):2209—13.5. Lerner-Geva L., Keinan-Boker L., Blumstein T. et al. Infertility, ovulation induction treatments and the incidence of breast cancer-a historical prospective cohort of Israeli women. Breast Cancer Res Treat 2006;100(2):201—12.Lerner-Geva L., Keinan-Boker L., Blumstein T. et al. Infertility, ovulation induction treatments and the incidence of breast cancer-a historical prospective cohort of Israeli women. Breast Cancer Res Treat 2006;100(2):201—12.ЛИТЕРАТУРА6. Ricci E., Parazzini F., Negri1 E. et al. Fertility drugs and the risk of breast can- cer. Hum Reprod 1999;14(6):1653—5.Ricci E., Parazzini F., Negri1 E. et al. Fertility drugs and the risk of breast can- cer. Hum Reprod 1999;14(6):1653—5.7. Brzezinski A., Peretz T., Mor-Yosef S. et al. Ovarian stimulation and breast can- cer: Is there a link? Gynecol Oncol 1994;52:292—5.Brzezinski A., Peretz T., Mor-Yosef S. et al. Ovarian stimulation and breast can- cer: Is there a link? Gynecol Oncol 1994;52:292—5.8. Burkman R., Tang M., Malone K. et al. Infertility drugs and the risk of breast cancer: findings from the National Institute of Child Health and Human development Women's Contraceptive and Reproductive Experiences Study. Fertil Steril 2003;7:844—51.Burkman R., Tang M., Malone K. et al. Infertility drugs and the risk of breast cancer: findings from the National Institute of Child Health and Human development Women's Contraceptive and Reproductive Experiences Study. Fertil Steril 2003;7:844—51.9. Potashnik G., Lerner-Geva L., Genkin L. et al. Fertility drugs and the risk of breast and ovarian cancers: results of a long-term follow-up study. Fertil Steril 1999;71:853—9.Potashnik G., Lerner-Geva L., Genkin L. et al. Fertility drugs and the risk of breast and ovarian cancers: results of a long-term follow-up study. Fertil Steril 1999;71:853—9.10. Bernstein L., Hanisch R., Sullivan-Halley J. et al. Treatment with human chorionic gonadotropin and riskBernstein L., Hanisch R., Sullivan-Halley J. et al. Treatment with human chorionic gonadotropin and riskof breast cancer. Cancer Epidemiol Biomark Prev 1995;4:437—40.11. Rossing M.A., Daling J.R., Weiss N.S. et al. Risk of breast cancer in a cohort of infertile women. Gynecol Oncol 1996;60:3—7.Rossing M.A., Daling J.R., Weiss N.S. et al. Risk of breast cancer in a cohort of infertile women. Gynecol Oncol 1996;60:3—7.12. Gauthier E., Paoletti X., Clavel-Chapelon F. Breast cancer risk associated with being treated for infertility: results from the French E3N cohort study. Hum Reprod 2004;19(10):2216—21.Gauthier E., Paoletti X., Clavel-Chapelon F. Breast cancer risk associated with being treated for infertility: results from the French E3N cohort study. Hum Reprod 2004;19(10):2216—21.13. Brinton L., Scoccia B., Moghissi K. et al. Breast cancer risk associated with ovulation stimulating drugs. Hum Reprod 2004;19(9):2005—13.Brinton L., Scoccia B., Moghissi K. et al. Breast cancer risk associated with ovulation stimulating drugs. Hum Reprod 2004;19(9):2005—13.14. Pappo I., Lerner-Geva L., Halevy A. The Possible Association between IVF and Breast Cancer Incidence. Ann Surg Oncol 2008;15(4):1048—55.Pappo I., Lerner-Geva L., Halevy A. The Possible Association between IVF and Breast Cancer Incidence. Ann Surg Oncol 2008;15(4):1048—55.15. Pappo I. Breast cancer in the elderly: histological, hormonal and surgical char- acteristics. Breast 2007;1:60—7.Pappo I. Breast cancer in the elderly: histological, hormonal and surgical char- acteristics. Breast 2007;1:60—7.