<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">397</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2014-0-3-64-69</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>GYNECOLOGY. DIAGNOSIS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ. ДИАГНОСТИКА</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Contrast enhanced magnetic resonance imaging for uterine artery embolization efficiency assessment in women with leiomyoma uteri</article-title><trans-title-group xml:lang="ru"><trans-title>Роль парамагнитных контрастных препаратов в оценке структур малого таза у женщин с лейомиомами матки при планировании эмболизации маточных артерий</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pavlovskaya</surname><given-names>Ye. A.</given-names></name><name xml:lang="ru"><surname>Павловская</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yukhno</surname><given-names>Ye. A.</given-names></name><name xml:lang="ru"><surname>Юхно</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>L55@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ryazanov</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Рязанов</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Trofimenko</surname><given-names>I. A.</given-names></name><name xml:lang="ru"><surname>Трофименко</surname><given-names>И. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sosin</surname><given-names>S. A.</given-names></name><name xml:lang="ru"><surname>Сосин</surname><given-names>С. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Serebryakova</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Серебрякова</surname><given-names>С. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Department of Roentgenology and Radiology with Course of Ultrasound Diagnosis, S.M. Kirov Military Medical Academy, Ministry of Defense of Russia, Saint Petersburg</institution></aff><aff><institution xml:lang="ru">Кафедра рентгенологии и радиологии с курсом ультразвуковой диагностики ФГБВОУ ВПО «Военно-медицинская академия им. С.М. Кирова» Минобороны России, Санкт-Петербург</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">City Hospital Forty, Saint Petersburg</institution></aff><aff><institution xml:lang="ru">СПбГБУЗ «Городская больница № 40»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">V.A. Almazov Federal Medicine Research Center, Ministry of Health, Saint Petersburg</institution></aff><aff><institution xml:lang="ru">ФГБУ «Федеральный медицинсий исследовательский центр им. В.А. Алмазова» Минздрава России, Санкт-Петербург</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">A.M. Nikiforov All-Russian Center of Emergency and Radiation Medicine, Ministry of Emergency Situations of Russia, Saint Petersburg</institution></aff><aff><institution xml:lang="ru">ФГБУ «Всероссийский центр экстренной и радиационной медицины им. А.М. Никифорова» МЧС России, Санкт-Петербург</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-11-07" publication-format="electronic"><day>07</day><month>11</month><year>2014</year></pub-date><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>64</fpage><lpage>69</lpage><history><date date-type="received" iso-8601-date="2014-11-07"><day>07</day><month>11</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-11-07"><day>07</day><month>11</month><year>2014</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/397">https://ojrs.abvpress.ru/ojrs/article/view/397</self-uri><abstract xml:lang="en"><p>Uterine artery embolization (UAE) is minimally invasive, less complicated and uterine-preserve procedure when compared to traditional surgical options. Magnetic resonance imaging (MRI) is the preferred modality in gynecologic pathology visualization. MRI is more accurate than transvaginal ultrasound in evaluating number, size and structure of the fibroids as well as their vascularization (by means of contrast enhancement) on pre-UAE uterus. On post-UAE contrast enhanced MRI, performed in 1, 6 and 12 month after the procedure, shrinkage of fibroids as well as the absence of their enhancement can be registered, showing the success or the manipulation. In case when leiomyoma is accompanied with adenomyosis, poor response of UAE can be noted by means of enhanced MRI revealing revascularization of fibroids. Thus, enhanced MRI is essential in UAE efficiency assessment, predicting treatment response and it’s complications.</p></abstract><trans-abstract xml:lang="ru"><p>Эмболизация маточных артерий (ЭМА) является органосохраняющим методом и представляет собой доступную и технически простую альтернативу традиционным хирургическим методикам. Магнитно-резонансная томография (МРТ) на сегодняшний день является «золотым стандартом» в диагностике патологии малого таза у женщин. Выполнение МРТ малого таза перед процедурой эмболизации позволяет более точно по сравнению с ультразвуковым исследованием локализовать лейомиоматозные узлы, а также определить тип их строения и степень васкуляризации по накоплению ими контрастного препарата. Проведение исследования с внутривенным контрастированием через 1, 6 и 12 мес после процедуры дает информацию о ее эффективности, оцениваемой по отсутствию накопления контрастного препарата лейомиомами, а также по уменьшению объема матки и узлов. В случае сочетания лейомиом матки с эндометриозом у пациенток, подвергающихся эмболизации, использование метода может выявить реваскуляризацию узлов. Применение парамагнитных контрастных препаратов позволяет более точно определять гистологический тип лейомиомы, а также является незаменимым для оценки эффективности ЭМА и выявления осложнений.</p></trans-abstract><kwd-group xml:lang="en"><kwd>leiomyoma</kwd><kwd>uterine artery embolization</kwd><kwd>magnetic resonance imaging</kwd><kwd>pelvis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>лейомимома</kwd><kwd>эмболизация маточных артерий</kwd><kwd>магнитно-резонансная томография</kwd><kwd>малый таз</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Zimmermann A., Bernuit D., Gerlinger C. et al. Prevalence, symptoms and management of uterine fibroids: an international internetbased survey of 21,746 women. BMC Womens Health 2012;12:6.</mixed-citation><mixed-citation xml:lang="ru">Zimmermann A., Bernuit D., Gerlinger C. et al. Prevalence, symptoms and management of uterine fibroids: an international internetbased survey of 21,746 women. BMC Womens Health 2012;12:6.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Kido A., Ascher S.M., Kishimoto K. et al. Comparison of uterine peristalsis before and after uterine artery embolization at 3-T MRI. AJR 2011;196(6):1431–5.</mixed-citation><mixed-citation xml:lang="ru">Kido A., Ascher S.M., Kishimoto K. et al. Comparison of uterine peristalsis before and after uterine artery embolization at 3-T MRI. AJR 2011;196(6):1431–5.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Hillard P.J.A. Benign diseases of the female reproductive tract: symptoms and signs. In: J.S. Berek, P.J.A. Hillard, E.Y. Adashi, eds. Novak’s gynecology. 13th ed. Philadelphia: Lippincott Williams &amp; Wilkins, 2002. P. 351– 420.</mixed-citation><mixed-citation xml:lang="ru">Hillard P.J.A. Benign diseases of the female reproductive tract: symptoms and signs. In: J.S. Berek, P.J.A. Hillard, E.Y. Adashi, eds. Novak’s gynecology. 13th ed. Philadelphia: Lippincott Williams &amp; Wilkins, 2002. P. 351– 420.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Сидорова И.С., Унанян А.Л., Агеев М.Б. и др. Современное состояние вопроса о патогенезе, клинике, диагностике и лечении миомы матки у женщин репродуктивного возраста. Акуш гин, репрод 2012;6(4):22–8.</mixed-citation><mixed-citation xml:lang="ru">Сидорова И.С., Унанян А.Л., Агеев М.Б. и др. Современное состояние вопроса о патогенезе, клинике, диагностике и лечении миомы матки у женщин репродуктивного возраста. Акуш гин, репрод 2012;6(4):22–8.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Вихляева Е.М. Руководство по диагностике и лечению больных лейомиомой матки. М.: МЕДпресс-информ, 2004. 400 с.</mixed-citation><mixed-citation xml:lang="ru">Вихляева Е.М. Руководство по диагностике и лечению больных лейомиомой матки. М.: МЕДпресс-информ, 2004. 400 с.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Руководство по лучевой диагностике в гинекологии. Под ред. Г.Е. Труфанова, В.О. Панова. СПб.: ЭЛБИ, 2008. 590 с.</mixed-citation><mixed-citation xml:lang="ru">Руководство по лучевой диагностике в гинекологии. Под ред. Г.Е. Труфанова, В.О. Панова. СПб.: ЭЛБИ, 2008. 590 с.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Тихомиров А.М., Олейник Ч.Г., Лубнин Д.М. Тактика лечения больных миомой матки. Методическое пособие для врачей акушеров-гинекологов. М.: Медицинское информационное агентство, 2007. 176 с.</mixed-citation><mixed-citation xml:lang="ru">Тихомиров А.М., Олейник Ч.Г., Лубнин Д.М. Тактика лечения больных миомой матки. Методическое пособие для врачей акушеров-гинекологов. М.: Медицинское информационное агентство, 2007. 176 с.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Bulman J.C., Ascher S.M., Spies J.B. Current concepts in uterine fibroid embolization. Radiographics 2012;32(6): 1735–50.</mixed-citation><mixed-citation xml:lang="ru">Bulman J.C., Ascher S.M., Spies J.B. Current concepts in uterine fibroid embolization. Radiographics 2012;32(6): 1735–50.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9. Walker W.J., Pelage J.P. Uterine artery embolization for symptomatic fibroids: clinical results in 400 women with imaging follow-up. BJOG 2002;109(11):1262–72.</mixed-citation><mixed-citation xml:lang="ru">Walker W.J., Pelage J.P. Uterine artery embolization for symptomatic fibroids: clinical results in 400 women with imaging follow-up. BJOG 2002;109(11):1262–72.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10. Spies J.B., Ascher S.A., Roth A.R. et al. Uterine artery embolization for leiomyomata. Obstet Gynecol 2001;98(1):29–34.</mixed-citation><mixed-citation xml:lang="ru">Spies J.B., Ascher S.A., Roth A.R. et al. Uterine artery embolization for leiomyomata. Obstet Gynecol 2001;98(1):29–34.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11. Moss J., Cooper K., Khaund A. et al. Randomized comparison of uterine artery embolization (UAE) with surgical treatment in patients with symptomatic uterine fibroids (REST trial): 5-year results. BJOG 2011; 118(8):936–44.</mixed-citation><mixed-citation xml:lang="ru">Moss J., Cooper K., Khaund A. et al. Randomized comparison of uterine artery embolization (UAE) with surgical treatment in patients with symptomatic uterine fibroids (REST trial): 5-year results. BJOG 2011; 118(8):936–44.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12. Tomislav S., Josip M., Liana C.S. et al. Uterine artery embolization as nonsurgical treatment of uterine myomas ISRN. Obstet Gynecol 2011;2011:489281.</mixed-citation><mixed-citation xml:lang="ru">Tomislav S., Josip M., Liana C.S. et al. Uterine artery embolization as nonsurgical treatment of uterine myomas ISRN. Obstet Gynecol 2011;2011:489281.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13. Hubert J., Bergin D. Imaging the female pelvis: when should MRI be considered. Appl Radiol 2008;37(1):9–24.</mixed-citation><mixed-citation xml:lang="ru">Hubert J., Bergin D. Imaging the female pelvis: when should MRI be considered. Appl Radiol 2008;37(1):9–24.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14. Siddiqui N., Nikolaidis P., Hammond N., Miller F.H. Uterine artery embolization: preand postprocedual evaluation using magnetic resonance imaging. Abdom Imaging 2013; 38(5):1161–77.</mixed-citation><mixed-citation xml:lang="ru">Siddiqui N., Nikolaidis P., Hammond N., Miller F.H. Uterine artery embolization: preand postprocedual evaluation using magnetic resonance imaging. Abdom Imaging 2013; 38(5):1161–77.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15. Spielmann A.L., Keogh C., Forster B.B. et al. Comparison of MRI and sonography in the preliminary evaluation for fibroid embolization. AJR Am J Roentgenol 2006;187(6):1499–504.</mixed-citation><mixed-citation xml:lang="ru">Spielmann A.L., Keogh C., Forster B.B. et al. Comparison of MRI and sonography in the preliminary evaluation for fibroid embolization. AJR Am J Roentgenol 2006;187(6):1499–504.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16. Levens E.D., Wesley R., Premkumar A. et al. Magnetic resonance imaging and transvaginal ultrasound for determining fibroid burden: implications for clinical research. Am J Obstet Gynecol 2009;200(5): 537.e1–7.</mixed-citation><mixed-citation xml:lang="ru">Levens E.D., Wesley R., Premkumar A. et al. Magnetic resonance imaging and transvaginal ultrasound for determining fibroid burden: implications for clinical research. Am J Obstet Gynecol 2009;200(5): 537.e1–7.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">17. Murase E., Siegelman E.S., Outwater E.K. et al. Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis and treatment. Radiographics 1999;19(5):1179–97.</mixed-citation><mixed-citation xml:lang="ru">Murase E., Siegelman E.S., Outwater E.K. et al. Uterine leiomyomas: histopathologic features, MR imaging findings, differential diagnosis and treatment. Radiographics 1999;19(5):1179–97.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">18. Rein M.S., Barbieri R.L., Friedman A.J. Progesterone: а critical role in the pathogenesis of uterine myomas. Am J Obstet Gynecol 1995:172(1 Pt 1):14–8.</mixed-citation><mixed-citation xml:lang="ru">Rein M.S., Barbieri R.L., Friedman A.J. Progesterone: а critical role in the pathogenesis of uterine myomas. Am J Obstet Gynecol 1995:172(1 Pt 1):14–8.</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">19. Ueda H., Togashi K., Konishi I. et al. Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics 1999;19 Spec No: S131–45.</mixed-citation><mixed-citation xml:lang="ru">Ueda H., Togashi K., Konishi I. et al. Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics 1999;19 Spec No: S131–45.</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">20. Weinreb J.C., Barkoff N.D., Megibow A., Demopoulos R. The value of MR imaging in distinguishing leiomyomas from other solid pelvic masses when sonography is indeterminate. AJR Am J Roentgenol 1990;154(2):295–9.</mixed-citation><mixed-citation xml:lang="ru">Weinreb J.C., Barkoff N.D., Megibow A., Demopoulos R. The value of MR imaging in distinguishing leiomyomas from other solid pelvic masses when sonography is indeterminate. AJR Am J Roentgenol 1990;154(2):295–9.</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">21. Sung E.R., Byun J.Y., Jung S.E. et al. CT and MRI of uterine sarcomas and their mimickers. AJR Am J Roentgenol 2003;181(5):1369–74.</mixed-citation><mixed-citation xml:lang="ru">Sung E.R., Byun J.Y., Jung S.E. et al. CT and MRI of uterine sarcomas and their mimickers. AJR Am J Roentgenol 2003;181(5):1369–74.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
