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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">406</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2014-0-4-29-34</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>MAMMOLOGY. DIAGNOSIS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>МАММОЛОГИЯ. ДИАГНОСТИКА</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Tactics of radiographic diagnostics of breast cancer in women with inherited predisposition</article-title><trans-title-group xml:lang="ru"><trans-title>Тактика лучевой диагностики рака молочной железы у женщин с наследственной предрасположенностью</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Karpova</surname><given-names>M. S.</given-names></name><name xml:lang="ru"><surname>Карпова</surname><given-names>М. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>mskarpova@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Korzhenkova</surname><given-names>G. P.</given-names></name><name xml:lang="ru"><surname>Корженкова</surname><given-names>Г. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lyubchenko</surname><given-names>L. N.</given-names></name><name xml:lang="ru"><surname>Любченко</surname><given-names>Л. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Cancer, Moscow</institution></aff><aff><institution xml:lang="ru">ФГБНУ «Российский онкологический научный центр им. Н.Н. Блохина» , Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-11-08" publication-format="electronic"><day>08</day><month>11</month><year>2014</year></pub-date><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>29</fpage><lpage>34</lpage><history><date date-type="received" iso-8601-date="2015-01-06"><day>06</day><month>01</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-01-06"><day>06</day><month>01</month><year>2015</year></date></history><permissions><copyright-year>2014</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/406">https://ojrs.abvpress.ru/ojrs/article/view/406</self-uri><abstract xml:lang="en"><p>With conventional approaches to mammography tissue examination in women over 40 years of age, mammography has been found to be lesseffective for a group of younger women with negative family histories (cancer in the family) and BRCA1 and BRCA2 gene mutation carriers.A distinct approach to mammography tissue examination in women with a hereditary disposition, involving additional examination methodswith due regard for age, is therefore suggested.</p></abstract><trans-abstract xml:lang="ru"><p>Сегодня разработана тактика обследования ткани молочных желез у женщин старше 40 лет. Но группа женщин с наследственной предрасположенностью требует отдельного подхода с использованием дополнительных методов обследования и учетом возрастных особенностей ткани молочных желез. Маммография оказалась малоэффективной в группе молодых женщин с отягощенным семейным анамнезом (семейный рак) и носителей мутаций генов BRCA1 и BRCA2. В связи с этим встал вопрос о введении в скрининговую программу женщин высокого риска дополнительных методов, которые бы позволили выявлять рак молочной железы в доклинической стадии.</p></trans-abstract><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>magnetic resonance imaging</kwd><kwd>mammography</kwd><kwd>BRCA1</kwd><kwd>BRCA2</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>магнитно-резонансная томография</kwd><kwd>маммография</kwd><kwd>BRCA1</kwd><kwd>BRCA2</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Breast Cancer Linkage Consortium (BCLC). Familial Cancer 2003;2(3–4):18–32.</mixed-citation><mixed-citation xml:lang="ru">Breast Cancer Linkage Consortium (BCLC). 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