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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">439</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2015-11-2-82-85</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>GYNECOLOGY. CLINICAL OBSERVATIONS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ. КЛИНИЧЕСКИЕ НАБЛЮДЕНИЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Laparoscopy in the treatment of cancer of the corpus uteri in patients with metabolic syndrome. A case report</article-title><trans-title-group xml:lang="ru"><trans-title>Лапароскопия в лечении рака тела матки у больных с метаболическим синдромом. Описание случая</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Berishvili</surname><given-names>A. I.</given-names></name><name xml:lang="ru"><surname>Беришвили</surname><given-names>А. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>aberishvili@yandex.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kochoyan</surname><given-names>T. M.</given-names></name><name xml:lang="ru"><surname>Кочоян</surname><given-names>Т. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Levkina</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Левкина</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nikolaenko</surname><given-names>L. O.</given-names></name><name xml:lang="ru"><surname>Николаенко</surname><given-names>Л. О.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center</institution></aff><aff><institution xml:lang="ru">ФГБНУ «РОНЦ им. Н.Н. Блохина»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">23 Kashirskoe Shosse, Moscow, 115478, Russia</institution></aff><aff><institution xml:lang="ru">Россия, 115478, Москва, Каширское шоссе, 23</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-07-21" publication-format="electronic"><day>21</day><month>07</month><year>2015</year></pub-date><volume>11</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>82</fpage><lpage>85</lpage><history><date date-type="received" iso-8601-date="2015-07-21"><day>21</day><month>07</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-07-21"><day>21</day><month>07</month><year>2015</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/439">https://ojrs.abvpress.ru/ojrs/article/view/439</self-uri><abstract xml:lang="en"><p>Today, the common term metabolic syndrome encompasses visceral (abdominal) obesity, glucose intolerance, type 2 diabetes mellitus (DM), hypertension, and dyslipidemia. In Europe, the rate of obesity mong the women ranges from 6 to 36 %. In the USA, 65 % of the adult population is overweight and 30 % is obese. High estrogen production in adipose tissue in patients with obesity has been established to increase the risk of cancer of the corpus uteri (CCU) by 4 times as compared to that in normal weight female patients. Furthermore, obese patients are at increased risk for DM that is also a risk factor for CCU. A rise in the number of obese patients leads to the population redistribution of gynecological cancer. The increasing number of patients with gynecological cancer is overweight. This patient group has an increased risk from surgery and anesthesia, a higher incidence of postoperative complications, and delayed recovery. Laparotomy increases the duration of hospital stay and the rate of wound complications. The frequency of urologic injuries in obese patients varies between 2 and 4 %. In this patient category, the rate of damage to the large vessels or bowels has also statistically significant differences. The literature highlights a number of complications specific to patients with obesity: trocar damage to anterior abdominal wall vessels, particularly to the inferior epigastric artery, urinary bladder, as well as trocar site hernia. The authors describe their experience in treating CCU patients with metabolic syndrome at the Department of Surgery for Female Reproductive System Tumors, N. N. Blokhin Russian Cancer Research Center. They demonstrate that laparoscopic extirpation of the uterus and its appendages can be performed in patients with third-degree obesity (weighing 174 kg) in Stage I CCU. It should be noted that this weight was previously regarded as an absolute contraindication to surgical treatment. Today, the active introduction of laparoscopic techniques into gynecological oncology and the improvement of anesthetic maintenance make it possible to virtually level off a contraindication to surgery, such as obesity, and to transfer it to a class of indications. An examination algorithm and the clinical features of the disease are given.</p></abstract><trans-abstract xml:lang="ru"><p>На сегодняшний день висцеральное (абдоминальное) ожирение, нарушение толерантности к глюкозе, сахарный диабет (СД) 2-го типа, артериальная гипертензия, дислипидемия объединяются под единым термином «метаболический синдром». В Европе частота больных ожирением колеблется от 6 до 36 % среди женщин. В США 65 % взрослого населения имеют избыточный вес, а 30 % страдают ожирением. Установлено, что большая выработка эстрогенов жировой тканью у больных ожирением в 4 раза увеличивает риск развития рака тела матки (РТМ) по сравнению с пациентками без избыточного веса. Кроме того, больные с ожирением имеют повышенный риск развития СД, также являющегося фактором риска развития РТМ. Рост числа больных ожирением ведет к перераспределению в популяции гинекологического рака. Все больше пациентов с онкогинекологической патологией имеют избыточный вес. Эта группа больных имеет повышенный риск хирургического и анестезиологического пособия, большую частоту послеоперационных осложнений и характеризуется замедлением выздоровления. Лапаротомия увеличивает продолжительность госпитализации и повышает частоту раневых осложнений. Встречаемость урологических повреждений у больных ожирением колеблется в пределах 2–4 %. Частота повреждения крупных сосудов или кишок у данной категории больных также не имеет статистически значимых различий. В литературе отмечен ряд осложнений, специфичных для больных ожирением: повреждение троакаром сосудов передней брюшной стенки, особенно нижней эпигастральной артерии, мочевого пузыря, а также грыжа троакарного отверстия. Представлен собственный опыт лечения больных РТМ с метаболическим синдромом в хирургическом отделении опухолей женской репродуктивной системы ФГБНУ «РОНЦ им. Н. Н. Блохина». Продемонстрирована возможность выполнения лапароскопической экстирпации матки с придатками у пациентки с ожирением III степени (вес 174 кг) при РТМ I стадии. Следует отметить, что раньше такой вес являлся абсолютным противопоказанием к хирургическому лечению. Сегодня активное внедрение лапароскопических методик в онкогинекологию и совершенствование анестезиологического пособия позволяют практически нивелировать такое противопоказание к хирургическому вмешательству, как ожирение, и перевести его в разряд показаний. Приводится алгоритм обследования и описаны особенности клинического течения заболевания.</p></trans-abstract><kwd-group xml:lang="en"><kwd>laparoscopy</kwd><kwd>cancer of the corpus uteri</kwd><kwd>metabolic syndrome</kwd><kwd>extirpation of the uterus and its appendage</kwd><kwd>, obesity</kwd><kwd>surgery</kwd><kwd>indications</kwd><kwd>preparation</kwd><kwd>specific features</kwd><kwd>results</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>лапароскопия</kwd><kwd>рак тела матки</kwd><kwd>метаболический синдром</kwd><kwd>экстирпация матки с придатками</kwd><kwd>ожирение</kwd><kwd>хирургия</kwd><kwd>показания</kwd><kwd>подготовка</kwd><kwd>особенности</kwd><kwd>результаты</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Eltabbakh G.H., Shamonki M.I., Moody J.M., Garafano L.L. Hysterectomy for obese women with endometrial cancer: laparoscopy or laparotomy? 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