Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press4410.17650/1994-4098-2013-0-1-2-72-82GYNECOLOGY. DIAGNOSISГИНЕКОЛОГИЯ. ДИАГНОСТИКАCerebral metastases of endometrial carcinoma. Diagnostic and neurosurgical aspectsЦеребральные метастазы рака эндометрия. Диагностические и нейрохирургические аспектыSevyanN. V.СевянН. В.
Russian Federation
hope-sev@yandex.ruKarakhanV. B.КараханВ. Б.
Russian Federation
TsybulskayaYu. A.ЦыбульскаяЮ. А.
Russian Federation
BondarenkoYu. V.БондаренкоЮ. В.
Russian Federation
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowФГБУ «РОНЦ им. Н.Н. Блохина» РАМН, Москва210520131-2728221072014210720142013https://ojrs.abvpress.ru/ojrs/article/view/44

Central nervous system (CNS) involvement by endometrial carcinoma is uncommon. Among 1710 patients registered for brain metastases at our institution between 1990 and 2012, 3 (0.18 %) developed brain metastases. All lesions (1 multiple, 2 single) were contrast enhancing on com- puted tomography scans, and were located in the cerebrum (lobus occipitalis) in 2 cases. The CNS was the only site of detectable disease in 1 patient with recurrent disease. One patient received radiotherapy (survival, 3 months) and two underwent surgical resection of solitary metas- tasis followed by radiotherapy (survival = 3 and 5 months and alive to the present). Prognosis of patients with CNS metastases from endometrial carcinoma appears poor; however, in a selected group of patients early diagnosis followed by multimodal treatment may result in a palliation of the disease.

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