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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">565</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2017-13-4-63-70</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>GYNECOLOGY. ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ. ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">HERBAL MEDICINAL PRODUCTS IN A TREATMENT OF MASTALGIA IN GYNECOLOGIC PATIENTS</article-title><trans-title-group xml:lang="ru"><trans-title>ФИТОПРЕПАРАТЫ В ЛЕЧЕНИИ ГИНЕКОЛОГИЧЕСКИХ БОЛЬНЫХ С ВЫРАЖЕННОЙ МАСТАЛГИЕЙ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kedrova</surname><given-names>A. G.</given-names></name><name xml:lang="ru"><surname>Кедрова</surname><given-names>А. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>28 Orekhovyy Boulevard, Moscow 115682</p></bio><bio xml:lang="ru"><p>Анна Генриховна Кедрова.</p><p>115682 Москва, Ореховый бульвар, 28</p></bio><email>kedrova.anna@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Levakov</surname><given-names>S. A.</given-names></name><name xml:lang="ru"><surname>Леваков</surname><given-names>С. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>91 Volokolamskoe Shosse, Moscow 125371</p></bio><bio xml:lang="ru"><p>125371 Москва, Волоколамское шоссе, 91</p></bio><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Federal Research and Clinical Center for Specialized Medical Cares and Medical Technologies, Federal Medical and Biological Agency of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинских технологий Федерального медико-биологического агентства России»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Institute for Advanced Training, Federal Medical and Biological Agency of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ДПО «Институт повышения квалификации Федерального медико-биологического агентства России»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-12-21" publication-format="electronic"><day>21</day><month>12</month><year>2017</year></pub-date><volume>13</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>63</fpage><lpage>70</lpage><history><date date-type="received" iso-8601-date="2017-12-22"><day>22</day><month>12</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-12-22"><day>22</day><month>12</month><year>2017</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/565">https://ojrs.abvpress.ru/ojrs/article/view/565</self-uri><abstract xml:lang="en"><p>Implementation of breast cancer screening using digital mammography improved the diagnosis of primary proliferative regressive structural changes in the breast, manifested as diffuse or diffusely-nodal deformations of tissues. Currently, women are significantly more likely to seek medical consultation for damages of the breast that could not be evaluated earlier. This requires the development of special tactics for their treatment and follow-up. Nowadays, searching for prognostic markers and choosing adequate therapy for nodular and diffuse mastopathy are among the most discussed issues in mammology, because up to 25 % of all breast cancer cases are diagnosed during the in situ phase. In this article we try to reassess the problem of dyshormonal changes in the breast and develop an optimal approach to their treatment.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящее время скрининг рака молочной железы путем цифровой маммографии улучшил диагностику начальных пролиферативных и регрессивных структурных изменений органа, проявляющихся в виде диффузных или диффузно-узловых деформаций тканей. Теперь все большее число женщин обращаются за консультациями по поводу повреждений молочной железы, которые в прошлом не оценивались, и это требует выработки специальной тактики наблюдения и терапии. Сегодня поиск маркеров прогноза и выбор адекватной терапии узловых и диффузных форм мастопатии – самые обсуждаемые вопросы клинических дискуссий, так как до 25 % всех выявляемых случаев рака молочной железы составляет рак in situ. Настоящая статья посвящена переосмыслению проблемы фоновых дисгормональных изменений тканей молочной железы и выработке оптимального подхода в их лечении.</p></trans-abstract><kwd-group xml:lang="en"><kwd>diffuse dyshormonal breast dysplasia</kwd><kwd>Mastodynon®</kwd><kwd>mastalgia</kwd><kwd>premenstrual syndrome</kwd><kwd>Vitex agnus-castus</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>диффузная дисгормональная дисплазия молочных желез</kwd><kwd>Мастодинон®</kwd><kwd>масталгия</kwd><kwd>предменструальный синдром</kwd><kwd>Vitex agnus-castus</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Seidlova-Wuttke D., Wuttke W. The premenstrual syndrome, premenstrual mastodynia, fibrocystic mastopathy and infertility have often common roots: effects of extracts of chasteberry (Vitex agnus-castus) as a solution. Clinical Phytoscience 2017;3:6. 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