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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">57</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2013-0-3-4-50-53</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>MAMMOLOGY. TREATMENT</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>МАММОЛОГИЯ. ЛЕЧЕНИЕ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Ten-year adjuvant hormone therapy for breast cancer: the pros and cons (a review of literature)</article-title><trans-title-group xml:lang="ru"><trans-title>Адъювантная гормонотерапия рака молочной железы длительностью 10 лет: за и против (обзор литературы)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Portnoy</surname><given-names>S. M.</given-names></name><name xml:lang="ru"><surname>Портной</surname><given-names>С. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shendrikova</surname><given-names>T. A.</given-names></name><name xml:lang="ru"><surname>Шендрикова</surname><given-names>Т. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>shendrikova.tatyana@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Cancer, Russian Academy of Medical Sciences, Moscow</institution></aff><aff><institution xml:lang="ru">ФГБУ «РОНЦ им. Н.Н. Блохина РАМН», Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-09-22" publication-format="electronic"><day>22</day><month>09</month><year>2013</year></pub-date><issue>3-4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>50</fpage><lpage>53</lpage><history><date date-type="received" iso-8601-date="2014-07-22"><day>22</day><month>07</month><year>2014</year></date><date date-type="accepted" iso-8601-date="2014-07-22"><day>22</day><month>07</month><year>2014</year></date></history><permissions><copyright-year>2013</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/57">https://ojrs.abvpress.ru/ojrs/article/view/57</self-uri><abstract xml:lang="en"><p>Tamoxifen is one of the basic drugs of adjuvant hormone therapy in patients with hormone-dependent breast tumors. The purpose of this paper is to analyze the results of randomized trials of long-term adjuvant hormone therapy for breast cancer.</p></abstract><trans-abstract xml:lang="ru"><p>ЦУ больных гормонально-зависимыми опухолями молочной железы тамоксифен является одним из основных препаратов адъю- вантной гормонотерапии. Целью данной статьи является анализ результатов 7 рандомизированных исследований по длительной адъювантной гормонотерапии рака молочной железы.</p></trans-abstract><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>adjuvant hormone therapy</kwd><kwd>tamoxifen</kwd><kwd>long-term results</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>адъювантная гормонотерапия</kwd><kwd>тамоксифен</kwd><kwd>отдаленные результаты</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. WHO Statistical Information System (WHOSIS). 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