Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press57710.17650/1994-4098-2018-14-1-47-51MAMMOLOGY. REVIEWSМАММОЛОГИЯ. ОБЗОРНЫЕ СТАТЬИMODERN VIEWS ON THE ROLE OF OVARIAN SUPPRESSION IN THE TREATMENT OF PATIENTS WITH HORMONE-DEPENDENT BREAST CANCER: SABCS-2017 NEWSСОВРЕМЕННЫЕ ВЗГЛЯДЫ НА РОЛЬ ОВАРИАЛЬНОЙ СУПРЕССИИ В ЛЕЧЕНИИ ПАЦИЕНТОК С ГОРМОНОЗАВИСИМЫМ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ: НОВОСТИ SABCS-2017BozhokA. A.БожокА. А.Russian Federation
68A Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758,
2 Litovskaya St., Saint Petersburg 194100
Божок Алла Александровна
197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68A, 194100 Санкт-Петербург, ул. Литовская, 2
allabozhok@mail.ruSaint Petersburg Clinical Research-Practical Center for Specialized Medical (Oncology) CaresГБУЗ «Санкт-Петербургский клинический научно-практический центр специализированных видов медицинской помощи (онкологический)»Department of reconstructive and plastic surgery, Saint Petersburg State Pediatric Medical University, Ministry of Health of RussiaКафедра реконструктивно-пластической хирургии ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет»1204201814147511104201811042018https://ojrs.abvpress.ru/ojrs/article/view/577
Interest in adjuvant endocrine therapy in the treatment of women with breast cancer does not fade for many years. In recent decades, more and more attention has been paid to the role of ovarian suppression. Recent publications and data from international congresses confirm the necessity of prescribing predominantly medicamentous ovarian suppression to women with breast cancer and preserved menstrual function not only as a therapy but also for fertility preservation.
Интерес к адъювантной эндокринотерапии в лечении женщин с раком молочной железы не угасает на протяжении многих лет. В последние десятилетия все больше внимания стало уделяться роли овариальной супрессии. Последние публикации и данные международных конгрессов подтверждают необходимость назначения преимущественно медикаментозной овариальной супрессии женщинам с диагнозом рака молочной железы, сохранившим менструальную функцию, не только в качестве терапии, но и для сохранения фертильности.
adjuvant endocrine therapyovarian function suppressiontamoxifenexemestanetriptorelinадъювантная эндокринотерапияовариальная супрессиятамоксифенэкземестантрипторелинBeatson G., Edin M. On the treatment of inoperable 10 cases of carcinoma of the mamma: suggestions for a new method of treatment of illustrative cases. Lancet 1896;148(3803):162–65. DOI: 10.1016/S0140-6736(01)72384-7.Early Breast Cancer Trialists’ Collaborative Group. Tamoxifen for early breast cancer: an overview of the randomised trials. Early Breast Cancer Trialists’ Collaborative Group. Lancet 1998;351(9114): 1451–67. PMID: 9605801.International Breast Cancer Study Group, Colleoni M., Gelber S. et al. Tamoxifen after adjuvant chemotherapy for premenopausal women with lymph node-positive breast cancer: International Breast Cancer Study Group Trial 13-93. J Clin Oncol 2006;24(9):1332–41. PMID: 16505417. DOI: 10.1200/JCO.2005.03.0783.Davidson N.E., O’Neill A.M., Vukov A.M. et al. Chemoendocrine therapy for premenopausal women with axillary lymph node-positive, steroid hormone receptorpositive breast cancer: results from INT 0101 (E5188). J Clin Oncol 2005;23(25):5973–82. PMID: 16087950. DOI: 10.1200/JCO.2005.05.551.LHRH-agonists in Early Breast Cancer Overview Group. Use of luteinising-hormonereleasing hormone agonists as adjuvant treatment in premenopausal patients with hormone-receptor-positive breast cancer: a meta-analysis of individual patient data from randomised adjuvant trials. Lancet 2007;369(9574):1711–23. PMID: 17512856. DOI: 10.1016/S01406736(07)60778-8.The ATAC Trialists Group. Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal woman with early breast cancer: first results of the ATAC randomized trial. Lancet 2002;359(9324): 2131–9. PMID: 12090977.Francis P.A., Regan M.M., Fleming G.F. et al. Adjuvant ovarian suppression in premenopausal breast cancer. N Engl J Med 2015;372(5):436–46. PMID: 25495490. DOI: 10.1056/NEJMoa1412379.Pagani О., Regan M.M., Walley B.A. et al. Adjuvant exemestane with ovarian suppression in premenopausal breast cancer. N Engl J Med 2014;37192:107–18. PMID: 24881463. DOI: 10.1056/NEJMoa1404037.Francis P.A., Regan M.M., Fleming G.F. et al. Adjuvant ovarian suppression in premenopausal breast cancer. N Engl J Med 2015;372(5):436–46. DOI: 10.1056/NEJMoa1412379.Fleming G., Francis P.A., Láng I. et atamoxifen (T) plus ovarian function suppression (OFS) versus tamoxifen in premenopausal women with hormone receptorpositive (HR+) early breast cancer (BC): update of the SOFT trial. SABCS-2017. Abstr. № 844 GS4-03.Francis P. on behalf of Pagani O., Regan M.M., Fleming G.F. et al. Randomized comparison of adjuvant aromatase inhibitor exemestane (E) plus ovarian function suppression (OFS) vs. tamoxifen (T) plus OFS in premenopausal women with hormone receptor positive (HR+) early breast cancer (BC): update of the combined TEXT and SOFT trials. SABCS-2017.Pagani O., Regan M.M., Fleming G.F. Randomized comparison of adjuvant aromatase inhibitor exemestane (E) plus ovarian function suppression (OFS) vs. tamoxifen (T) plus OFS in premenopausal women with hormone receptor positive (HR+) early breast cancer (BC): update of the combined TEXT and SOFT trials. SABCS-2017. Abstr. № 844 GS4-02.Lambertini M. Pooled analysis of five randomized trials investigating temporary ovarian suppression with gonadotropinreleasing hormone analogs during chemotherapy as a strategy to preserve ovarian function and fertility in premenopausal early breast cancer patients. SABCS-2017. Abstr. № 844 GS4-01.l. Randomized comparison of adjuvant DOI: 10.17650/1994‑4098‑2018‑14‑1‑47-51Lambertini M. Pooled analysis of five randomized trials investigating temporary ovarian suppression with gonadotropinreleasing hormone analogs during chemotherapy as a strategy to preserve ovarian function and fertility in premenopausal early breast cancer patients. SABCS-2017. Abstr. № 844 GS4-01.l. Randomized comparison of adjuvant DOI: 10.17650/1994‑4098‑2018‑14‑1‑47-51