Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press59210.17650/1994-4098-2018-14-2-36-41MAMMOLOGY. REVIEWSМАММОЛОГИЯ. ОБЗОРНЫЕ СТАТЬИVACUUM-ASSISTED ASPIRATION BIOPSY: MINIMALLY INVASIVE TREATMENT FOR BENIGN BREAST TUMORS (A LITERATURE REVIEW)ВАКУУМНАЯ АСПИРАЦИОННАЯ БИОПСИЯ: МАЛОИНВАЗИВНЫЙ МЕТОД ЛЕЧЕНИЯ ДОБРОКАЧЕСТВЕННОЙ ПАТОЛОГИИ МОЛОЧНЫХ ЖЕЛЕЗ (ОБЗОР ЛИТЕРАТУРЫ)LevchenkoK. F.ЛевченкоК. Ф.
Russian Federation

11 Kuznetskstroevskiy prospekt, Novokuznetsk 654007

25 Kutuzova St., Novokuznetsk 654041

654007 Новокузнецк, Кузнецкстроевский проспект, 11

654041 Новокузнецк, ул. Кутузова, 25

Кирилл Федорович Левченко 

kemnano@rambler.ruBaranovA. I.БарановА. И.
Russian Federation

11 Kuznetskstroevskiy prospekt, Novokuznetsk 654007

5 Stroiteley Prospekt, Novokuznetsk 654005

654007 Новокузнецк, Кузнецкстроевский проспект, 11

654005 Новокузнецк, проспект Строителей, 5 

Grand Medica LLCООО «Гранд Медика»Novokuznetsk Clinical Oncology DispensaryГБУЗ «Новокузнецкий клинический онкологический диспансер»Novokuznetsk State Institute of Postgraduate Medical Education, Ministry of Health of RussiaФГБОУ ДПО «Новокузнецкий государственный институт усовершенствования врачей» Минздрава России1508201814236411508201815082018https://ojrs.abvpress.ru/ojrs/article/view/592

Vacuum-assisted aspiration biopsy (VAB) has been in use for over 20 years. It is an accurate and safe procedure with a sensitivity of 97 %, specificity of 100 %, and accuracy of 99 %. VAB is used for the evaluation of nonpalpable tumors suspicious for breast cancer. Since 2000, VAB is widely used as a therapeutic method for total biopsy or resection of benign breast tumors (breast fibroadenoma, recurrent cysts, and intraductal or intracyctic hyperplasia). Many authors consider VAB as an alternative to standard surgery. VAB demonstrates good results in the minimally invasive treatment of nodular mastopathy. VAB technique is continuously being improved, which indicates the progress in medical science and successful implementation of minimally invasive treatments into clinical practice.

Метод вакуумной аспирационной биопсии (ВАБ) применяется в маммологии уже на протяжении 20 лет. Это точная и безопасная процедура, чувствительность метода составляет 97 %, специфичность достигает 100 %, точность – 99 %. Основным показанием для диагностического применения ВАБ является биопсия непальпируемых, подозрительных на рак новообразований молочной железы. С 2000 г. ВАБ широко применяется с терапевтической целью как метод тотальной биопсии или резекции доброкачественных образований молочных желез (фиброаденома молочной железы, рецидивирующие кисты, внутрипротоковые и внутрикистозные разрастания) и многими авторами рассматривается как альтернатива стандартному хирургическому вмешательству. Хорошие результаты получены при использовании ВАБ в малоинвазивном лечении узловых форм мастопатии. Метод ВАБ непрерывно развивается, что говорит о прогрессе в медицинской науке и успешном внедрении в клиническую практику малоинвазивных методов лечения.

breast biopsyvacuum-assisted aspiration biopsybreast tumorsfibroadenomaminimally invasive treatmentsбиопсия молочной железывакуумная аспирационная биопсияновообразования молочной железыфиброаденомамалоинвазивные методы лечения1. Parker S.H., Lovin J.D., Jobe W.E. et al. Stereotactic breast biopsy with a biopsy gun. Radiology 1990;176(3):741–7. DOI: 10.1148/radiology.176.3.2167501.Parker S.H., Lovin J.D., Jobe W.E. et al. Stereotactic breast biopsy with a biopsy gun. Radiology 1990;176(3):741–7. DOI: 10.1148/radiology.176.3.2167501.2. Parker S.H., Jobe W.E., Dennis M.A. et al. US-guided automated large-core breast biopsy. Radiology 1993;187(2):507–11. DOI: 10.1148/radiology.187.2.8475299.Parker S.H., Jobe W.E., Dennis M.A. et al. US-guided automated large-core breast biopsy. Radiology 1993;187(2):507–11. DOI: 10.1148/radiology.187.2.8475299.3. Povoski S.P., Jimenez R.E. A comprehensive evaluation of the 8-gauge vacuum-assisted Mammotome system for ultrasoundguided diagnostic biopsy and selective excision of breast lesions. World J Surg Oncol 2007;5:83. PMID: 17663769. DOI: 10.1186/1477- 7819-5-83.Povoski S.P., Jimenez R.E. A comprehensive evaluation of the 8-gauge vacuum-assisted Mammotome system for ultrasoundguided diagnostic biopsy and selective excision of breast lesions. World J Surg Oncol 2007;5:83. PMID: 17663769. DOI: 10.1186/1477- 7819-5-83.4. Parker S.H., Dennis M.A., Stavros A.T. et al. Ultrasound-guided mamtmeotomoy: a new breast biopsy technique. J Diagn Med Sonogr 1996;12(3):113–8.Parker S.H., Dennis M.A., Stavros A.T. et al. Ultrasound-guided mamtmeotomoy: a new breast biopsy technique. J Diagn Med Sonogr 1996;12(3):113–8.5. Burbank F., Parker S.H., Fogarty T.J. Stereotactic breast biopsy: improved tissue harvesting with the Mammotome. Am Surg 1996;62(9):738–44. PMID: 8751765.Burbank F., Parker S.H., Fogarty T.J. Stereotactic breast biopsy: improved tissue harvesting with the Mammotome. Am Surg 1996;62(9):738–44. PMID: 8751765.6. Hahn M., Krainick-Strobel U., Toellner T. et al. Interdisciplinary consensus recommendations for the use of vacuum-assisted breast biopsy under sonographic guidance: first update 2012. Ultraschall Med 2012;33(4):366– 71. DOI: 10.1055/s-0032-1312831.Hahn M., Krainick-Strobel U., Toellner T. et al. Interdisciplinary consensus recommendations for the use of vacuum-assisted breast biopsy under sonographic guidance: first update 2012. Ultraschall Med 2012;33(4):366– 71. DOI: 10.1055/s-0032-1312831.7. Cassano E., Urban L.A., Pizzamiglio M. et al. Ultrasound-guided vacuum-assisted core breast biopsy: experience with 406 cases. Breast Cancer Res Treat 2007;102(1):103–10. DOI: 10.1007/ s10549-006-9305-x.Cassano E., Urban L.A., Pizzamiglio M. et al. Ultrasound-guided vacuum-assisted core breast biopsy: experience with 406 cases. Breast Cancer Res Treat 2007;102(1):103–10. DOI: 10.1007/ s10549-006-9305-x.8. Carder P.J., Liston J.C. Will the spectrum of lesions prompting a B3 breast core biopsy increase the benign biopsy rate? J Clin Pathol 2003;56(2):133–8. PMID: 12560393.Carder P.J., Liston J.C. Will the spectrum of lesions prompting a B3 breast core biopsy increase the benign biopsy rate? J Clin Pathol 2003;56(2):133–8. PMID: 12560393.9. Kim M.J., Kim E.K., Kwak J.Y. et al. Nonmalignant papillary lesions of the breast at US-guided directional vacuumassisted removal: a preliminary report. Eur Radiol 2008;18(9):1774–83. DOI: 10.1007/s00330-008-0960-7.Kim M.J., Kim E.K., Kwak J.Y. et al. Nonmalignant papillary lesions of the breast at US-guided directional vacuumassisted removal: a preliminary report. Eur Radiol 2008;18(9):1774–83. DOI: 10.1007/s00330-008-0960-7.10. Kim M.J., Kim S.I., Youk J.H. et al. The diagnosis of non-malignant papillary lesions of the breast: comparison of ultrasound-guided automated gun biopsy and vacuum-assisted removal. Clin Radiol 2011;66(6):530–5. DOI: 10.1016/j. crad.2011.01.008.Kim M.J., Kim S.I., Youk J.H. et al. The diagnosis of non-malignant papillary lesions of the breast: comparison of ultrasound-guided automated gun biopsy and vacuum-assisted removal. Clin Radiol 2011;66(6):530–5. DOI: 10.1016/j. crad.2011.01.008.11. Hai-Lin Park, Lee Su Kim. The current role of vacuum assisted breast biopsy system in breast disease. J Breast Cancer 2011;14(1):1–7. DOI: 10.4048/ jbc.2011.14.1.1.Hai-Lin Park, Lee Su Kim. The current role of vacuum assisted breast biopsy system in breast disease. J Breast Cancer 2011;14(1):1–7. DOI: 10.4048/ jbc.2011.14.1.1.12. Ko E.S., Bae Y.A., Kim M.J. et al. Factors affecting the efficacy of ultrasound-guided vacuum-assisted percutaneous excision for removal of benign breast lesions. J Ultrasound Med 2008;27(1):65–73. PMID: 18096732.Ko E.S., Bae Y.A., Kim M.J. et al. Factors affecting the efficacy of ultrasound-guided vacuum-assisted percutaneous excision for removal of benign breast lesions. J Ultrasound Med 2008;27(1):65–73. PMID: 18096732.13. Ko E.S., Han H., Lee B.H. et al. Sonographic changes after removing all benign breast masses with sonographically guided vacuum-assisted biopsy. Acta Radiol 2009;50(9):968–74. DOI: 10.3109/02841850903130836.Ko E.S., Han H., Lee B.H. et al. Sonographic changes after removing all benign breast masses with sonographically guided vacuum-assisted biopsy. Acta Radiol 2009;50(9):968–74. DOI: 10.3109/02841850903130836.14. Alonso-Bartolome P., Vega-Bolívar A., Torres-Tabanera M. et al. Sonographically guided 11-G directional vacuum-assisted breast biopsy as an alternative to surgical excision: utility and cost study in probably benign lesions. Acta Radiol 2004;8(4):390–6. PMID: 15323390.Alonso-Bartolome P., Vega-Bolívar A., Torres-Tabanera M. et al. Sonographically guided 11-G directional vacuum-assisted breast biopsy as an alternative to surgical excision: utility and cost study in probably benign lesions. Acta Radiol 2004;8(4):390–6. PMID: 15323390.15. Fine R.E., Boyd B.A., Whitworth P.W. et al. Percutaneous removal of benign breast masses using a vacuum-assisted handheld device with ultrasound guidance. Am J Surg 2002;184(4):332–6. PMID: 12383895.Fine R.E., Boyd B.A., Whitworth P.W. et al. Percutaneous removal of benign breast masses using a vacuum-assisted handheld device with ultrasound guidance. Am J Surg 2002;184(4):332–6. PMID: 12383895.16. March D.E., Coughlin B.F., Barham R.B. et al. Breast masses: removal of all US evidence during biopsy by using a handheld vacuum-assisted device – initial experience. Radiology 2003;227(2):549–55. DOI: 10.1148/radiol.2272020476.March D.E., Coughlin B.F., Barham R.B. et al. Breast masses: removal of all US evidence during biopsy by using a handheld vacuum-assisted device – initial experience. Radiology 2003;227(2):549–55. DOI: 10.1148/radiol.2272020476.17. Papathemelis T., Heim S., Lux M. et al. Minimalli invasive breast fibroadenoma excision using an ultrasound-guided vacuum-assised biopsy device. Geburtshilfe Frauenheilkd 2017;77(2):176–81. DOI: 10.1055/s-0043-100387.Papathemelis T., Heim S., Lux M. et al. Minimalli invasive breast fibroadenoma excision using an ultrasound-guided vacuum-assised biopsy device. Geburtshilfe Frauenheilkd 2017;77(2):176–81. DOI: 10.1055/s-0043-100387.18. Zagouri F., Gounaris A., Liakou P. et al. Vacuum-assisted breast biopsy: more cores, more hematomas? In Vivo 2011;25(4):703–5. PMID: 21709018.Zagouri F., Gounaris A., Liakou P. et al. Vacuum-assisted breast biopsy: more cores, more hematomas? In Vivo 2011;25(4):703–5. PMID: 21709018.19. Zografos G.C., Zagouri F., Sergentanis T.N. et al. Minimizing underestimation rate of microcalcifications excised via vacuumassisted breast biopsy: a blind study. Breast Cancer Res Treat 2008;109(2):397–402. DOI: 10.1007/s10549-007-9662-0.Zografos G.C., Zagouri F., Sergentanis T.N. et al. Minimizing underestimation rate of microcalcifications excised via vacuumassisted breast biopsy: a blind study. Breast Cancer Res Treat 2008;109(2):397–402. DOI: 10.1007/s10549-007-9662-0.20. Wang Z.L., Liu G., Huang Y. et al. Percutaneous excisional biopsy of clinically benign breast lesions with vacuum-assisted system: comparison of three devices. Eur J Radiol 2012;81(4):725–30. DOI: 10.1016/j.ejrad.2011.01.059.Wang Z.L., Liu G., Huang Y. et al. Percutaneous excisional biopsy of clinically benign breast lesions with vacuum-assisted system: comparison of three devices. Eur J Radiol 2012;81(4):725–30. DOI: 10.1016/j.ejrad.2011.01.059.21. Lee S.H., Kim E.K., Kim M.J. et al. Vacuum-assisted breast biopsy under ultrasonographic guidance: analysis of a 10-year experience. Ultrasonography 2014;33(4):259–66. DOI: 10.14366/ usg.14020.Lee S.H., Kim E.K., Kim M.J. et al. Vacuum-assisted breast biopsy under ultrasonographic guidance: analysis of a 10-year experience. Ultrasonography 2014;33(4):259–66. DOI: 10.14366/ usg.14020.22. Park H.L., Min S.Y., Kwon S.H. et al. Nationwide survey of use of vacuum-assisted breast biopsy in South Korea. Anticancer Res 2012;32(12):5459–64. PMID: 23225452.Park H.L., Min S.Y., Kwon S.H. et al. Nationwide survey of use of vacuum-assisted breast biopsy in South Korea. Anticancer Res 2012;32(12):5459–64. PMID: 23225452.23. Johnson A.T., Henry-Tillman R.S., Smith L.F. et al. Percutaneous excisional breast biopsy. Am J Surg 2002;184(6): 550–4. PMID: 12488164.Johnson A.T., Henry-Tillman R.S., Smith L.F. et al. Percutaneous excisional breast biopsy. Am J Surg 2002;184(6): 550–4. PMID: 12488164.24. Fine R.E., Whitworth P.W., Kim J.A. et al Low-risk palpable breast masses removed using a vacuum-assisted handheld device. Am J Surg 2003;186(4):362–7. PMID: 14553851.Fine R.E., Whitworth P.W., Kim J.A. et al Low-risk palpable breast masses removed using a vacuum-assisted handheld device. Am J Surg 2003;186(4):362–7. PMID: 14553851.25. Sebag P., Tourasse C., Rouyer N. et al. Value of vacuum assisted biopsies under sonography guidance: results from a multicentric study of 650 lesions. J Radiol 2006;87(1):29–34. PMID: 16415777.Sebag P., Tourasse C., Rouyer N. et al. Value of vacuum assisted biopsies under sonography guidance: results from a multicentric study of 650 lesions. J Radiol 2006;87(1):29–34. PMID: 16415777.26. Wang W.J., Wang Q., Cai Q.P. et al. Ultrasonographically guided vacuum-assisted excision for multiple breast masses: nonrandomizedcomparison with conventional open excision. J Surg Oncol 2009;100(8):675–80. DOI: 10.1002/ jso.21394.Wang W.J., Wang Q., Cai Q.P. et al. Ultrasonographically guided vacuum-assisted excision for multiple breast masses: nonrandomizedcomparison with conventional open excision. J Surg Oncol 2009;100(8):675–80. DOI: 10.1002/ jso.21394.27. Yao F., Li J., Wan Y. et al Sonographically guided vacuum-assisted breast biopsy for complete excision of presumed benignbreast lesions. J Ultrasound Med 2012;31(12):1951–7. PMID: 23197548.Yao F., Li J., Wan Y. et al Sonographically guided vacuum-assisted breast biopsy for complete excision of presumed benignbreast lesions. J Ultrasound Med 2012;31(12):1951–7. PMID: 23197548.28. Baez E., Huber A., Vetter M. et al Minimal invasive complete excision of benign breast tumors using a three-dimensional ultrasound-guided mammotome vacuum device. Ultrasound Obstet Gynecol 2003;21(3):267–72. DOI: 10.1002/uog.74.Baez E., Huber A., Vetter M. et al Minimal invasive complete excision of benign breast tumors using a three-dimensional ultrasound-guided mammotome vacuum device. Ultrasound Obstet Gynecol 2003;21(3):267–72. DOI: 10.1002/uog.74.29. Plantade R., Hammou J.C., Gerard F. et al. Ultrasound-guided vacuum-assisted biopsy: review of 382 cases. J Radiol 2005;86(9 Pt 1):1003–15. PMID: 16224340.Plantade R., Hammou J.C., Gerard F. et al. Ultrasound-guided vacuum-assisted biopsy: review of 382 cases. J Radiol 2005;86(9 Pt 1):1003–15. PMID: 16224340.30. Kibil W., Hodorowicz-Zaniewska D., Szczepanik A. et al. Ultrasound-guided vacuum-assisted core biopsy in the diagnosis and treatment of focal lesions of the breast – own experience. Wideochir Inne Tech Maloinwazyjne 2013;8(1):63–8. DOI: 10.5114/wiitm.2011.31630.Kibil W., Hodorowicz-Zaniewska D., Szczepanik A. et al. Ultrasound-guided vacuum-assisted core biopsy in the diagnosis and treatment of focal lesions of the breast – own experience. Wideochir Inne Tech Maloinwazyjne 2013;8(1):63–8. DOI: 10.5114/wiitm.2011.31630.31. Яковец Е.А. Оптимизация хирургического лечения доброкачественных образований молочной железы у женщин репродуктивного возраста. Автореф. … канд. мед. наук. Новосибирск, 2015. 18 с. [Yakovets E.A. Optimization of surgical treatment of benign breast tumors in women of reproductive age. Summary of thesis … of candidate of medical science. Novosibirsk, 2015. 18 p. (In Russ.)].Яковец Е.А. Оптимизация хирургического лечения доброкачественных образований молочной железы у женщин репродуктивного возраста. Автореф. … канд. мед. наук. Новосибирск, 2015. 18 с. [Yakovets E.A. Optimization of surgical treatment of benign breast tumors in women of reproductive age. Summary of thesis … of candidate of medical science. Novosibirsk, 2015. 18 p. (In Russ.)].32. Grady I., Gorsuch H., Wilburn-Bailey S. Long-term outcome of benign fibroadenomas treated by ultrasound-guided percutaneous excision. Breast J 2008;14(3):275–8. DOI: 10.1111/j.1524-4741.2008.00574.x.Grady I., Gorsuch H., Wilburn-Bailey S. Long-term outcome of benign fibroadenomas treated by ultrasound-guided percutaneous excision. Breast J 2008;14(3):275–8. DOI: 10.1111/j.1524-4741.2008.00574.x.33. Tagaya N., Nakagawa A., Ishikawa Y. et al. Experience with ultrasonographically guided vacuum-assisted resection of benign breast tumors. Clin Radiol 2008;63(4):396–400. DOI: 10.1016/j. crad.2007.06.012.Tagaya N., Nakagawa A., Ishikawa Y. et al. Experience with ultrasonographically guided vacuum-assisted resection of benign breast tumors. Clin Radiol 2008;63(4):396–400. DOI: 10.1016/j. crad.2007.06.012.34. Park H.L., Kwak J.Y., Jung H. et al. Is mammotome excision feasible for benign breast masses bigger than 3 cm in the greatest dimension? J Kor Surg Soc 2006;70:25–9.Park H.L., Kwak J.Y., Jung H. et al. Is mammotome excision feasible for benign breast masses bigger than 3 cm in the greatest dimension? J Kor Surg Soc 2006;70:25–9.35. Kolman S., Zonderlabd M.H. Fibroadenomen verwijderen met vacuumbiopsie. Ned Tijdschr Geneeskd 2011;155:1–3.Kolman S., Zonderlabd M.H. Fibroadenomen verwijderen met vacuumbiopsie. Ned Tijdschr Geneeskd 2011;155:1–3.36. Kim M.J., Park B.W., Kim S.I. et al. Long-term follow-up results for ultrasound-guided vacuum-assisted removal of benign palpable breast mass. Am J Surg 2010;199(1):1–7. DOI: 10.1016/j.amjsurg.2008.11.037.Kim M.J., Park B.W., Kim S.I. et al. Long-term follow-up results for ultrasound-guided vacuum-assisted removal of benign palpable breast mass. Am J Surg 2010;199(1):1–7. DOI: 10.1016/j.amjsurg.2008.11.037.37. Li S., Wu J., Chen K. et al. Clinical outcomes of 1578 Chinese patients with breast benign diseases after ultrasound-guided vacuum-assisted excision: recurrence and the risk factors. Am J Surg 2013;205(1):39–44. DOI: 10.1016/j.amjsurg.2012.02.021.Li S., Wu J., Chen K. et al. Clinical outcomes of 1578 Chinese patients with breast benign diseases after ultrasound-guided vacuum-assisted excision: recurrence and the risk factors. Am J Surg 2013;205(1):39–44. DOI: 10.1016/j.amjsurg.2012.02.021.38. Jlang Y., Lan H., Ye Q. et al. Mammotome® biopsy system for the resection of breast lesions: Clinical experience in two high-volume teaching hospitals. Exp Ther Med 2013; 6(3):759–64. Doi: 10.3892/ etm.2013.1191.Jlang Y., Lan H., Ye Q. et al. Mammotome® biopsy system for the resection of breast lesions: Clinical experience in two high-volume teaching hospitals. Exp Ther Med 2013; 6(3):759–64. Doi: 10.3892/ etm.2013.1191.39. Sperber F., Blank A., Metser U. et al. Diagnosis and treatment of breast fibroadenomas by ultrasound-guided vacuum-assisted biopsy. Arch Surg 2003;138(7):796–800. DOI: 10.1001/archsurg.138.7.796.Sperber F., Blank A., Metser U. et al. Diagnosis and treatment of breast fibroadenomas by ultrasound-guided vacuum-assisted biopsy. Arch Surg 2003;138(7):796–800. DOI: 10.1001/archsurg.138.7.796.40. Peters M.E., Fagerholm M.I., Scanlan K.A. et al. Mammographic evaluation of the postsurgical and irradiated breast. Radiographics 1988;8(5):873–99. DOI: 10.1148/radiographics.8.5.3227129.Peters M.E., Fagerholm M.I., Scanlan K.A. et al. Mammographic evaluation of the postsurgical and irradiated breast. Radiographics 1988;8(5):873–99. DOI: 10.1148/radiographics.8.5.3227129.41. Zografos G.C., Zagouri F., Sergentanis T.N. et al. Hematoma after vacuum-assisted breast biopsy: are interleukins predictors? Onkologie 2009;32(7):395–7. DOI: 10.1159/000219366.Zografos G.C., Zagouri F., Sergentanis T.N. et al. Hematoma after vacuum-assisted breast biopsy: are interleukins predictors? Onkologie 2009;32(7):395–7. DOI: 10.1159/000219366.42. Zagouri F., Sergentanis T.N., Domeyer P. et al. Volume of blood suctioned during vacuum-assisted breast biopsy predicts later hematoma formation. BMC Research Notes 2010;70(3):1–4. DOI: 10.1186/1756-0500-3-70.Zagouri F., Sergentanis T.N., Domeyer P. et al. Volume of blood suctioned during vacuum-assisted breast biopsy predicts later hematoma formation. BMC Research Notes 2010;70(3):1–4. DOI: 10.1186/1756-0500-3-70.43. Połom K., Murawa D., Nowaczyk P. et al. Vacuum-assisted core-needle biopsy as a diagnostic and therapeutic method in lesions radiologically suspicious of breast fibroadenoma Rep Pract Oncol Radiother 2010;16(1):32–5. DOI: 10.1016/j.rpor.2010.12.001.Połom K., Murawa D., Nowaczyk P. et al. Vacuum-assisted core-needle biopsy as a diagnostic and therapeutic method in lesions radiologically suspicious of breast fibroadenoma Rep Pract Oncol Radiother 2010;16(1):32–5. DOI: 10.1016/j.rpor.2010.12.001.44. Thurley P., Evans A., Hamilton L. et al. Patient satisfaction and efficacy of vacuum-assisted excision biopsy of fibroadenomas. Clin Radiol 2009;64(4):381–5. DOI: 10.1016/j.crad.2008.09.013.Thurley P., Evans A., Hamilton L. et al. Patient satisfaction and efficacy of vacuum-assisted excision biopsy of fibroadenomas. Clin Radiol 2009;64(4):381–5. DOI: 10.1016/j.crad.2008.09.013.45. Yu-Mee Sohn, Min Jung Kim, EunKyung Kim et al. Pseudoaneurysm of the breast during vacuum-assisted removal. J Ultrasound Med 2009;28(7):967– 71. PMID: 19546340.Yu-Mee Sohn, Min Jung Kim, EunKyung Kim et al. Pseudoaneurysm of the breast during vacuum-assisted removal. J Ultrasound Med 2009;28(7):967– 71. PMID: 19546340.46. El Khoury M., Mesurolle B., Kao E. et al. Spontaneous thrombosis of pseudoaneurysm of thebreast related to core biopsy. AJR Am J Roentgenol 2007;189(6):309– 11. DOI: 10.2214/AJR.05.1647.El Khoury M., Mesurolle B., Kao E. et al. Spontaneous thrombosis of pseudoaneurysm of thebreast related to core biopsy. AJR Am J Roentgenol 2007;189(6):309– 11. DOI: 10.2214/AJR.05.1647.47. Bazzocchi M., Francescutti G.E., Zuiani C. et al. Breast pseudoaneurysm in a woman after core biopsy: percutaneous treatment with alcohol. AJR Am J. Roentgenol 2002;179(3):696–8. DOI: 10.2214/ ajr.179.3.1790696.Bazzocchi M., Francescutti G.E., Zuiani C. et al. Breast pseudoaneurysm in a woman after core biopsy: percutaneous treatment with alcohol. AJR Am J. Roentgenol 2002;179(3):696–8. DOI: 10.2214/ ajr.179.3.1790696.48. Dixon A.M., Enion D.S. Pseudoaneurysm of the breast: case study and review of literature. Br J Radiol 2004;77(920):694–7. DOI: 10.1259/bjr/55440225.Dixon A.M., Enion D.S. Pseudoaneurysm of the breast: case study and review of literature. Br J Radiol 2004;77(920):694–7. DOI: 10.1259/bjr/55440225.49. Beres R.A., Harrington D.G., Wenzel M.S. Percutaneous repair of breast pseudoaneurysm: sonographically guided embolization. AJR Am J Roentgenol 1997;169(2):425–7. DOI: 10.2214/ ajr.169.2.9242746.Beres R.A., Harrington D.G., Wenzel M.S. Percutaneous repair of breast pseudoaneurysm: sonographically guided embolization. AJR Am J Roentgenol 1997;169(2):425–7. DOI: 10.2214/ ajr.169.2.9242746.50. Yom C.K., Moon B.I., Choe K.J. et al. Long-term results after excision of breast mass using a vacuum-assisted biopsy device. ANZ J Surg. 2009;79(11):794–8. DOI: 10.1111/j.1445-2197.2009.05103.x.Yom C.K., Moon B.I., Choe K.J. et al. Long-term results after excision of breast mass using a vacuum-assisted biopsy device. ANZ J Surg. 2009;79(11):794–8. DOI: 10.1111/j.1445-2197.2009.05103.x.51. Simon J.R., Kalbhen C.L., Cooper R.A. et al. Accuracy and complications of USguided vacuum-assisted core breast biopsy. Radiology 2000;215(3);694–7. DOI: 10.1148/radiology.215.3.r00jn37694.Simon J.R., Kalbhen C.L., Cooper R.A. et al. Accuracy and complications of USguided vacuum-assisted core breast biopsy. Radiology 2000;215(3);694–7. DOI: 10.1148/radiology.215.3.r00jn37694.52. Куликов В.Г., Яковец Е.А. Инновационные подходы в хирургии молочной железы. Современные проблемы науки и образования 2015;(1–1):1301. Доступно по: http://www.science-education. ru/121-17429. [Kulikov V.G., Yakovets E.A. Innovative approaches to breast surgery. Sovremennye problemy nauki i obrazovaniya = Current Problems of Science and Education 2015;(1–1):1301. Available at: http://www.science-education.ru/121- 17429. (In Russ.)].Куликов В.Г., Яковец Е.А. Инновационные подходы в хирургии молочной железы. Современные проблемы науки и образования 2015;(1–1):1301. Доступно по: http://www.science-education. ru/121-17429. [Kulikov V.G., Yakovets E.A. Innovative approaches to breast surgery. Sovremennye problemy nauki i obrazovaniya = Current Problems of Science and Education 2015;(1–1):1301. Available at: http://www.science-education.ru/121- 17429. (In Russ.)].53. Куликов В.Г., Яковец Е.А., Александрова О.Н. и др. Маммотомия как актуальный метод диагностики и лечения доброкачественных образований молочных желез. Медицина и образование в Сибири 2012;(6):31. Доступно по: https://www.science-education.ru/ pdf/2015/1/187.pdf. [Kulikov V.G., Yakovets E.A., Aleksandrova O.N. et al. Mammotomy as an actual method for the diagnosis and treatment of benign breast tumors. Meditsina i obrazovanie v Sibiri = Medicine and Education in Siberia 2012;(6):31. Available at: https://www.science-education.ru/ pdf/2015/1/187.pdf. (In Russ.)].Куликов В.Г., Яковец Е.А., Александрова О.Н. и др. Маммотомия как актуальный метод диагностики и лечения доброкачественных образований молочных желез. Медицина и образование в Сибири 2012;(6):31. Доступно по: https://www.science-education.ru/ pdf/2015/1/187.pdf. [Kulikov V.G., Yakovets E.A., Aleksandrova O.N. et al. Mammotomy as an actual method for the diagnosis and treatment of benign breast tumors. Meditsina i obrazovanie v Sibiri = Medicine and Education in Siberia 2012;(6):31. Available at: https://www.science-education.ru/ pdf/2015/1/187.pdf. (In Russ.)].54. Ясков Н.М., Чижик А.В., Нохрин Д.Д. Опыт применения вакуумной дрельбиопсии в диагностике и лечении узловых образований молочных желез. Тюменский медицинский журнал 2010;(3–4):31–2. [Yaskov N.M., Chizhik A.V., Nokhrin D.D. Vacuum-assisted drill biopsy in the diagnosis and treatment of breast nodules. Tymenskiy meditsinskiy zhurnal = Tyumen Medical Journal 2010;(3–4):31–2. (In Russ.)].Ясков Н.М., Чижик А.В., Нохрин Д.Д. Опыт применения вакуумной дрельбиопсии в диагностике и лечении узловых образований молочных желез. Тюменский медицинский журнал 2010;(3–4):31–2. [Yaskov N.M., Chizhik A.V., Nokhrin D.D. Vacuum-assisted drill biopsy in the diagnosis and treatment of breast nodules. Tymenskiy meditsinskiy zhurnal = Tyumen Medical Journal 2010;(3–4):31–2. (In Russ.)].55. Torres-Tabanera M., Alonso-Bartolomé P., Vega-Bolivar A. et al. Percutaneous microductectomy with a directional vacuum-assisted system guided by ultrasonography for the treatment of breast discharge: experience in 63 cases. Acta Radiol 2008;49(3):271–6. DOI: 10.1080/02841850701769793.Torres-Tabanera M., Alonso-Bartolomé P., Vega-Bolivar A. et al. Percutaneous microductectomy with a directional vacuum-assisted system guided by ultrasonography for the treatment of breast discharge: experience in 63 cases. Acta Radiol 2008;49(3):271–6. DOI: 10.1080/02841850701769793.56. Wei H., Jiayi F., Qinping Z. et al. Ultrasound-guided vacuum-assisted breast biopsy system for diagnosis and minimally invasive excision of intraductal papilloma without nipple discharge. World J Surg 2009;33(12):2579–81. DOI: 10.1007/ s00268-009-0171-7.Wei H., Jiayi F., Qinping Z. et al. Ultrasound-guided vacuum-assisted breast biopsy system for diagnosis and minimally invasive excision of intraductal papilloma without nipple discharge. World J Surg 2009;33(12):2579–81. DOI: 10.1007/ s00268-009-0171-7.57. Bonaventure T., Cormier B., Lebas P. et al. Benign papilloma: is US-guided vacuumassisted breast biopsy an alternative to surgical biopsy? J Radiol 2007;88(9 Pt 1):1165–8. PMID: 17878878.Bonaventure T., Cormier B., Lebas P. et al. Benign papilloma: is US-guided vacuumassisted breast biopsy an alternative to surgical biopsy? J Radiol 2007;88(9 Pt 1):1165–8. PMID: 17878878.58. Chang J.M., Cho N., Moon W.K. et al. Does ultrasound-guided directional vacuum-assisted removal help eliminate abnormal nipple discharge in patients with benign intraductal single mass? Korean J Radiol 2009;10(6):575–80. DOI: 10.3348/ kjr.2009.10.6.575.Chang J.M., Cho N., Moon W.K. et al. Does ultrasound-guided directional vacuum-assisted removal help eliminate abnormal nipple discharge in patients with benign intraductal single mass? Korean J Radiol 2009;10(6):575–80. DOI: 10.3348/ kjr.2009.10.6.575.59. Shin H.J., Kim H.H., Kim S.M. et al. Papillary lesions of the breast diagnosed at percutaneous sonographically guided biopsy: comparison of sonographic features and biopsy methods. AJR Am J Roentgenol 2008; 190(3):630–6. DOI: 10.2214/AJR.07.2664.Shin H.J., Kim H.H., Kim S.M. et al. Papillary lesions of the breast diagnosed at percutaneous sonographically guided biopsy: comparison of sonographic features and biopsy methods. AJR Am J Roentgenol 2008; 190(3):630–6. DOI: 10.2214/AJR.07.2664.60. Маммология: национальное руководство. Под ред. В.П. Харченко, Н.И. Рожковой. М.: ГЭОТАР-Медиа, 2009. C. 72–78. [Mammalogy: national guidelines. Eds.: V.P. Kharchenko, N.I. Rozhkova. Moscow: GEOTAR-Media, 2009. Pp. 72–78. (In Russ.)].Маммология: национальное руководство. Под ред. В.П. Харченко, Н.И. Рожковой. М.: ГЭОТАР-Медиа, 2009. C. 72–78. [Mammalogy: national guidelines. Eds.: V.P. Kharchenko, N.I. Rozhkova. Moscow: GEOTAR-Media, 2009. Pp. 72–78. (In Russ.)].