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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">609</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2018-14-3-71-76</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>GYNECOLOGY. ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ГИНЕКОЛОГИЯ. ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Non-invasive cervical cancer during pregnancy. Prognosis for mothers and children</article-title><trans-title-group xml:lang="ru"><trans-title>Беременность, ассоциированная с неинвазивным раком шейки матки. Прогноз для матерей и детей</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Verbitskaya</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Вербитская</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>41 Kirochnaya St., Saint Petersburg 191015 </p></bio><bio xml:lang="ru"><p>191015 Санкт-Петербург, ул. Кирочная, 41</p><p/></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Urmancheeva</surname><given-names>A. F.</given-names></name><name xml:lang="ru"><surname>Урманчеева</surname><given-names>А. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>41 Kirochnaya St., Saint Petersburg 191015</p><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758 </p></bio><bio xml:lang="ru"><p>191015 Санкт-Петербург, ул. Кирочная, 41</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68 </p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Artemyeva</surname><given-names>A. S.</given-names></name><name xml:lang="ru"><surname>Артемьева</surname><given-names>А. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758 </p></bio><bio xml:lang="ru"><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68 </p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mikhetko</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Михетько</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758 </p></bio><bio xml:lang="ru"><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68 </p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Novik</surname><given-names>V. I.</given-names></name><name xml:lang="ru"><surname>Новик</surname><given-names>В. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758 </p></bio><bio xml:lang="ru"><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68 </p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Berlev</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Берлев</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>41 Kirochnaya St., Saint Petersburg 191015</p><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758 </p></bio><bio xml:lang="ru"><p>191015 Санкт-Петербург, ул. Кирочная, 41 </p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68 </p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mikaya</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Микая</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758 </p></bio><bio xml:lang="ru"><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68 </p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ulrikh</surname><given-names>E. A.</given-names></name><name xml:lang="ru"><surname>Ульрих</surname><given-names>Е. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>41 Kirochnaya St., Saint Petersburg 191015</p><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758</p><p>2 Litovskaya St., Saint Petersburg 194100 </p></bio><bio xml:lang="ru"><p>191015 Санкт-Петербург, ул. Кирочная, 41</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p><p>194100 Санкт-Петербург, ул. Литовская, 2 </p></bio><email>elenaulrikh@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.I. Mechnikov North-Western State Medical University Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Северо-Западный государственный медицинский университет им. И.И. Мечникова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.N. Petrov National Medical Research Center of Onclology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Петрова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВО «Санкт-Петербургский государственный педиатрический медицинский университет»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-10-16" publication-format="electronic"><day>16</day><month>10</month><year>2018</year></pub-date><volume>14</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>71</fpage><lpage>76</lpage><history><date date-type="received" iso-8601-date="2018-10-16"><day>16</day><month>10</month><year>2018</year></date><date date-type="accepted" iso-8601-date="2018-10-16"><day>16</day><month>10</month><year>2018</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/609">https://ojrs.abvpress.ru/ojrs/article/view/609</self-uri><abstract xml:lang="en"><p>The problem of malignant tumors in pregnant women is becoming increasingly relevant in recent years primarily due to the postponement of childbirth. In 2014, the mean age of Russian women at first birth was 28.1 years, whereas in 1995, mean age was 24.9 years (Russian annual demographic report for 2015). Cervical carcinoma (primarily preinvasive) is the most common gynecologic malignancy in pregnant women. The doctor and the patient have to choose between immediate treatment and preservation of pregnancy, and, therefore, delayed anticancer therapy. We analyzed 17-year experience of managing pregnant women with non-invasive cervical cancer followed up in the N.N. Petrov National Medical Research Center of Onclology, Ministry of Health of Russia, and also summarized the strategy used in the diagnosis, treatment and monitoring of such patients.</p></abstract><trans-abstract xml:lang="ru"><p>Актуальность сочетания злокачественных опухолей с беременностью возрастает с каждым годом. В первую очередь это связано с отсрочкой деторождения. Так, в 2014 г. средний возраст российских женщин при рождении ребенка составлял 28,1 года, в отличие от 24,9 года в 1995 г. (по данным демографического ежегодника России за 2015 г.). Самой частой онкогинекологической опухолью, сочетающейся с беременностью, является карцинома шейки матки. При этом наиболее распространенной клинической ситуацией является преинвазивный рак шейки матки. Врач и пациент оказываются перед выбором незамедлительного лечения либо сохранения беременности и отсроченного лечения опухоли. В статье проанализирован 17-летний опыт ведения больных неинвазивным раком шейки матки на фоне беременности на базе ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Петрова» Минздрава России и резюмирована тактика диагностики, лечения и наблюдения таких пациенток.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cervical cancer</kwd><kwd>cervical intraepithelial neoplasia</kwd><kwd>CIN</kwd><kwd>human papillomavirus</kwd><kwd>HPV</kwd><kwd>pregnancy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак шейки матки</kwd><kwd>цервикальная интраэпителиальная неоплазия</kwd><kwd>ЦИН</kwd><kwd>вирус папилломы человека</kwd><kwd>ВПЧ</kwd><kwd>беременность</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Ahdoot D., van Nostrand K.M., Nguyen N.J., Tewari D.S. The effect of route of delivery on regression of abnormal cervical cytologic findings in the postpartum period. Am J Obstet Gynecol 1998;178(6):1116–20. PMID: 9662288.</mixed-citation><mixed-citation xml:lang="ru">Ahdoot D., van Nostrand K.M., Nguyen N.J., Tewari D.S. 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