Tumors of female reproductive systemTumors of female reproductive systemОпухоли женской репродуктивной системы1994-40981999-8627Publishing House ABV Press64710.17650/1994-4098-2019-15-2-42-51MAMMOLOGY. ORIGINAL REPORTSМАММОЛОГИЯ. ОРИГИНАЛЬНЫЕ СТАТЬИOral contraceptives and menopausal hormone therapy as breast cancer risk categoriesПероральные контрацептивы и менопаузальная гормональная терапия как категории риска рака молочной железыhttps://orcid.org/0000-0001-8814-636XVуsotskayaI. V.ВысоцкаяИ. В.
Russian Federation

8/2 Trubetskaya St., Моscow 119991

Ирина Викторовна Высоцкая 

119991 Москва, ул. Трубецкая, 8, стр. 2

vysotskaya.irina@mail.ruhttps://orcid.org/0000-0001-9959-626XLetyaginV. P.ЛетягинВ. П.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0001-6699-0738VorotnikovI. K.ВоротниковИ. К.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0003-0040-3136KirsanovV. U.КирсановВ. Ю.
Russian Federation

8/2 Trubetskaya St., Моscow 119991

119991 Москва, ул. Трубецкая, 8, стр. 2

https://orcid.org/0000-0002-2481-0791GladilinaI. A.ГладилинаИ. А.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0003-4893-8770KimE. A.КимЕ. А.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

I.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaФГАОУ ВО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России (Сеченовский Университет)N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России0609201915242510609201906092019https://ojrs.abvpress.ru/ojrs/article/view/647

The research provided includes analysis of the current state of the problem on the use of oral contraceptives and menopausal hormone therapy. These therapeutic options were evaluated in terms of their importance for the risk of breast cancer. The possibility of using these drugs in a cohort of high-risk patients (women with family history of breast cancer) and in the group of patients with benign pathology was analyzed as well. Modern trends of menopausal hormone therapy prescription in different clinical situations were determined.

В представленной работе проведен анализ современного состояния проблемы использования пероральных контрацептивов и менопаузальной гормональной терапии. Данные терапевтические опции оценены с позиции их значимости для риска развития злокачественной патологии молочных желез, а также проанализированы возможности применения данных препаратов в когорте пациенток повышенного риска рака молочной железы (женщины с отягощенным семейным анамнезом) и в группе больных с доброкачественной патологией молочной железы. Определены современные тенденции назначения менопаузальной гормональной терапии в различных клинических ситуациях.

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