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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">761</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2020-16-3-12-17</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>MAMMOLOGY. ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>МАММОЛОГИЯ. ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Assessment of risk of loss of the implant in two-stage breast reconstruction</article-title><trans-title-group xml:lang="ru"><trans-title>Оценка риска потери имплантата при двухэтапной реконструкции молочной железы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1345-6579</contrib-id><name-alternatives><name xml:lang="en"><surname>Shivilov</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Шивилов</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Entusiastov Highway, Moscow 111123</p></bio><bio xml:lang="ru"><p><bold>Евгений Витальевич Шивилов</bold></p><p>111123 Москва, шоссе Энтузиастов, 86</p></bio><email>shivilov@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kvetenadze</surname><given-names>G. E.</given-names></name><name xml:lang="ru"><surname>Кветенадзе</surname><given-names>Г. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Entusiastov Highway, Moscow 111123</p></bio><bio xml:lang="ru"><p>111123 Москва, шоссе Энтузиастов, 86</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Arslanov</surname><given-names>Kh. S.</given-names></name><name xml:lang="ru"><surname>Арсланов</surname><given-names>Х. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Entusiastov Highway, Moscow 111123</p></bio><bio xml:lang="ru"><p>111123 Москва, шоссе Энтузиастов, 86</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tseplina</surname><given-names>O. E.</given-names></name><name xml:lang="ru"><surname>Цеплина</surname><given-names>О. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>86 Entusiastov Highway, Moscow 111123</p></bio><bio xml:lang="ru"><p>111123 Москва, шоссе Энтузиастов, 86</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">A.S. Loginov Moscow Clinical Scientific Center, Moscow Healthcare Department</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Московский клинический научный центр им. А.С. Логинова» Департамента здравоохранения г. Москвы</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2020-12-01" publication-format="electronic"><day>01</day><month>12</month><year>2020</year></pub-date><volume>16</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>12</fpage><lpage>17</lpage><history><date date-type="received" iso-8601-date="2021-01-12"><day>12</day><month>01</month><year>2021</year></date><date date-type="accepted" iso-8601-date="2021-01-12"><day>12</day><month>01</month><year>2021</year></date></history><permissions><copyright-year>2020</copyright-year><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/761">https://ojrs.abvpress.ru/ojrs/article/view/761</self-uri><abstract xml:lang="en"><p>Surgical treatment remains one of the leading methods in the treatment of breast cancer. Every year, the number of breast reconstruction operations is steadily increasing. But the number of possible complications associated with performing such operations also increases. Breast reconstruction using an expander may be one of the acceptable options for patients who are planning radiation therapy. The article analyzes the results of two-stage reconstructive plastic surgery on the breast in the complex treatment of patients diagnosed with breast cancer. In 90.5 % of cases, a good cosmetic result was obtained. The risk of losing the implant after chemotherapy was 4.8 % and 13.9 % for chemotherapy combined with radiation therapy, respectively. Two-stage breast reconstruction can be used with careful selection of patients.</p></abstract><trans-abstract xml:lang="ru"><p>Хирургическое лечение остается одним из ведущих методов в лечении рака молочной железы. Ежегодно количество операций по восстановлению молочной железы неуклонно возрастает. Но также увеличивается и количество возможных осложнений, связанных с выполнением таких операций. Восстановление молочной железы с использованием экспандера может быть одним из приемлемых вариантов для пациенток, которым планируется лучевая терапия. В статье проанализированы результаты выполнения двухэтапных реконструктивно-пластических операций на молочной железе при комплексном лечении пациенток с диагнозом рака молочной железы. В 90,5 % случаев получен хороший косметический результат. Риск потери имплантата после проведения химиотерапии составил 4,8 %, при проведении химиотерапии в сочетании лучевой терапией – 13,9 %. Двухэтапную реконструкцию молочной железы можно использовать при тщательном отборе пациенток.</p></trans-abstract><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>reconstructive surgery</kwd><kwd>two-stage reconstruction</kwd><kwd>endoprosthesis</kwd><kwd>complications</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>реконструктивная операция</kwd><kwd>двухэтапная реконструкция</kwd><kwd>эндопротезирование</kwd><kwd>осложнения</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Bray F., Ferlay J., Soerjomataram I. et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2018;68(6):394–424. DOI: 10.3322/caac.21492.</mixed-citation></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Malignant neoplasms in Russia in 2018 (morbidity and mortality). 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