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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Tumors of female reproductive system</journal-id><journal-title-group><journal-title xml:lang="en">Tumors of female reproductive system</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли женской репродуктивной системы</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1994-4098</issn><issn publication-format="electronic">1999-8627</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">930</article-id><article-id pub-id-type="doi">10.17650/1994-4098-2022-18-1-20-24</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>MAMMOLOGY. ORIGINAL REPORTS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>МАММОЛОГИЯ. ОРИГИНАЛЬНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Long-term outcomes of oncoplastic breast resection with local perforator flaps</article-title><trans-title-group xml:lang="ru"><trans-title>Отдаленные результаты применения онкопластических резекций молочной железы с замещением дефекта перемещенными локальными перфорантными лоскутами</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shatova</surname><given-names>Iu. S.</given-names></name><name xml:lang="ru"><surname>Шатова</surname><given-names>Ю. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><bold>Iuliana Sergeevna Shatova </bold></p><p><italic>63 14-ya liniya St., Rostov-on-Don 344037, Russia</italic></p><p> </p></bio><bio xml:lang="ru"><p><bold>Юлиана Сергеевна Шатова</bold></p><p><italic>344037 Ростов-на-Дону, ул. 14-я линия 63</italic></p></bio><email>shat5@rambler.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Maksimova</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Максимова</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>63 14-ya liniya St., Rostov-on-Don 344037, Russia</italic></p></bio><bio xml:lang="ru"><p><italic>344037 Ростов-на-Дону, ул. 14-я линия 63</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vashchenko</surname><given-names>I. N.</given-names></name><name xml:lang="ru"><surname>Ващенко</surname><given-names>А. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>63 14-ya liniya St., Rostov-on-Don 344037, Russia</italic></p></bio><bio xml:lang="ru"><p><italic>344037 Ростов-на-Дону, ул. 14-я линия 63</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shevchenko</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Шевченко</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>63 14-ya liniya St., Rostov-on-Don 344037, Russia</italic></p></bio><bio xml:lang="ru"><p><italic>344037 Ростов-на-Дону, ул. 14-я линия 63</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Chernikov</surname><given-names>E. N.</given-names></name><name xml:lang="ru"><surname>Черникова</surname><given-names>Е. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>63 14-ya liniya St., Rostov-on-Don 344037, Russia</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">National Medical Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2022-05-08" publication-format="electronic"><day>08</day><month>05</month><year>2022</year></pub-date><volume>18</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>20</fpage><lpage>24</lpage><history><date date-type="received" iso-8601-date="2022-05-07"><day>07</day><month>05</month><year>2022</year></date></history><permissions><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://ojrs.abvpress.ru/ojrs/article/view/930">https://ojrs.abvpress.ru/ojrs/article/view/930</self-uri><abstract xml:lang="en"><p><bold>Background. </bold>Oncoplastic breast resections with perforator flaps are relatively common now; however, many studies demonstrate contradictory results, especially in terms of long-term outcomes.</p><p><bold>Objective: </bold>to assess short-term and long-term outcomes of oncoplastic breast resection with defect repair using perforator flaps.</p><p><bold>Materials and methods. </bold>This study included 62 breast cancer patients who underwent oncoplastic breast resection with defect repair using local perforator flaps, including lateral intercostal artery perforator (LICAP) flaps (40.3 %), lateral thoracic artery perforator (LTAP) (19.4 %), anterior intercostal artery perforator (AICAP) (27.4 %), and medial intercostal artery perforator (MICAP) (12.9 %) flaps. The assessment of oncological, functional, and aesthetic outcomes was performed in patients who were followed-up for at least a year (<italic>n </italic>= 57). Mean follow-up time was 26.5 months (range: 14–38 months).</p><p><bold>Results. </bold>The following complications were registered among the patients studied: seroma in the area of excised primary tumor (8.1 %), insufficient blood supply of the flap that caused focal lipofibrosis/liponecrosis (3.2 %), positive resection margin (3.2 %), low position of the submammary fold (11.3 %), locoregional recurrence (0 %), generalized process (3.5 %). All women evaluated their functional and aesthetic result as good or excellent. According to BCCT.core 3.0, 91.3 % of patients achieved good and excellent results.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Введение. </bold>Онкопластические резекции с замещением дефекта перемещенными перфорантными лоскутами являются относительно распространенными операциями, но данные литературы носят разрозненный характер, особенно в аспекте отдаленных результатов.</p><p><bold>Цель исследования </bold>– оценить непосредственные и отдаленные результаты применения онкопластических резекций молочной железы с замещением дефекта перемещенными локальными перфорантными лоскутами.</p><p><bold>Материалы и методы. </bold>В исследование вошли 62 пациентки, которым этапом комплексного лечения по поводу рака молочной железы была выполнена онкопластическая резекция с замещением дефекта молочной железы вариантом перемещенного перфорантного локального лоскута (LICAP – 40,3 %, LTAP – 19,4 %, AICAP – 27,4 %, MICAP – 12,9 %). Оценка отдаленных результатов – как онкологических, так и функционально-эстетических – проводилась у пациенток со сроком наблюдения более года (<italic>n</italic><italic> </italic>= 57). средний срок наблюдения – 26,5 (14–38) мес.</p><p><bold>Результаты. </bold>серома в области удаленной первичной опухоли – 8,1 % случаев, недостаточность кровоснабжения лоскута, приведшая к очаговому липофиброзу/липонекрозу, – 3,2 %, положительный край резекции – 3,2 %, занижение субмаммарной складки – 11,3 %, локорегионарный рецидив – 0 %, генерализация процесса – 3,5 % случаев. функционально-эстетический результат отличный и хороший – 100 % по оценке пациенток и 91,3 % по критериям программы BCCT.core 3.0.</p></trans-abstract><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>oncoplastic resection</kwd><kwd>perforator flap</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>онкопластические резекции</kwd><kwd>перемещенный перфорантный лоскут</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Hamdi M., Van Landuyt K., Monstrey S., Blondeel P. Pedicled perforator flaps in breast reconstruction: a new concept. Brit J Plast Surg 2004;57(6):531–9. DOI: 10.1016/j.bjps.2004.04.015.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Kim J.B, Eom J.R., Lee J.W. et al. Utility of two surgical techniques usinga lateral intercostal artery perforator flap after breast-conserving surgery: a singlecenter retrospective study. Plast Reconstr Surg 2019;143(3):477e–487e. DOI: 10.1097/PRS.0000000000005374.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>McCulley S.J., Schaverien M.V., Tan V.K. et al. Lateral thoracic artery perforator (LTAP) flap in partial breast reconstruction. J Plast Reconstr Aesthet Surg 2015;68(5):686–91. DOI: 10.1016/j.bjps.2015.01.008. 27.</mixed-citation></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">Hamdi M. Oncoplastic and reconstructive surgery of the breast. Breast 2013;22(S2):S100–S105 DOI: 10.1016/j.breast.2013.07.019.</mixed-citation><mixed-citation xml:lang="ru">Hamdi M. Oncoplastic and reconstructive surgery of the breast. Breast 2013;22(S2):S100–S105 DOI: 10.1016/j.breast.2013.07.019.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">Shatova Iu.S., Vashchenko L.N., Maksimova N.A. et al. Oncoplastic resection with trasferred perforator flaps for breast cancer patients with small/ moderate volume breasts. Kazanskiy meditsinskiy zhurnal = Kazan Medical Journal 2020;101(1):119–23. (In Russ.). DOI: 10.17816/KMJ2020-119.</mixed-citation><mixed-citation xml:lang="ru">Шатова Ю.С., Ващенко Л.Н., Максимова Н.А. и др. Онкопластические резекции с использованием перемещенных перфорантных лоскутов у пациенток с раком молочной железы и малым/средним объемом молочных желез. Казанский медицинский журнал 2020;101(1):119–23.. DOI: 10.17816/KMJ2020-119.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><mixed-citation>Soumian S., Parmeshwar R., Chandarana M. et al. Chest wall perforator flaps for partial breast reconstruction: Surgical outcomes from a multicenter study. Arch Plast Surg 2020;47(2):153–9. DOI: 10.5999/aps.2019.01186.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Hu J.T.A., Tenovici A., Parulekar V. et al. The impact of partial breast reconstruction with lateral chest wall perforator flaps on post-operative cancer surveillance. Ann Breast Surg 2018;2(10):10. DOI: 10.21037/abs.2018.04.01.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Clough K.B., van la Parra R.F.D., Thygesen H.H. et al. Long-term results after oncoplastic surgery for breast cancer: a 10-year follow-up. Ann Surg 2018;268(1):165–71.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Roy P.G., Mustata L., Hu J. et al. Partial breast reconstruction with lateral chest wall perforator flap to facilitate breast conservation in breast cancer: first 100 cases with cancer outcomes at 8 years follow-up and the lessons learned. Cancer Manag Res 2021;13:9453–66. DOI: 10.2147/CMAR.S321192.</mixed-citation></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">Cardoso M.J., Cardoso J.S., Oliveira P.H., Gouveia P. The breast cancer conservative treatment. Cosmetic results – BCCT.core – software for objective assessment of esthetic outcome in breast cancer conservative treatment: A narrative review. Comput Methods Programs Biomed 2016;126:154–9. DOI:10.1016/j.cmpb.2015.11.010.</mixed-citation><mixed-citation xml:lang="ru">Cardoso M.J., Cardoso J.S., Oliveira P.H., Gouveia P. The breast cancer conservative treatment. Cosmetic results – BCCT.core – software for objective assessment of esthetic outcome in breast cancer conservative treatment: A narrative review. Comput Methods Programs Biomed 2016;126:154–9. DOI: 10.1016/j.cmpb.2015.11.010.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><mixed-citation>Joshi S., Jaiswal D., Chougle Q. et al. Transposition flap for the oncoplastic reconstruction of outer quadrant breast defects. J Plast Reconstr Aesthet Surg 2021;74(9):2176–83.</mixed-citation></ref></ref-list></back></article>
