Trophoblastic neoplasia on the background of developing pregnancy: a rare gynecological tumor with a chance of favorable outcome for mother and fetus
E. A. Ulrikh,
E. L. Dikareva,
A. D. Dzharbaeva,
O. A. Zhamborova,
T. M. Pervuninа,
E. V. Komlichenko,
S. A. Protsenko,
G. M. Teletaeva,
O. A. Li,
A. S. Artemyeva,
I. A. Mashenko,
G. F. Kutusheva,
T. Yu. Semiglazova,
А. F. Urmancheeva https://doi.org/10.17650/1994-4098-2022-18-3-112-117
Abstract
Trophoblastic neoplasias are rare tumors, accounting for less than 1 % of malignant neoplasms of the female genital tract. Trophoblastic tumors associated with developing pregnancy are extremely rare. The article presents the successful experience of diagnostics and treatment of intraplacental chorioncarcinoma associated with progressing pregnancy.
About the Authors
E. A. Ulrikh
V.A. Almazov National Medical Research Center, Ministry of Health of Russia; N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia; I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Elena Aleksandrovna Ulrikh
2 Akkuratova St., Saint Petersburg 197341
68 Leningradskaya St., Pesochny, Saint Petersburg 197758
41 Kirochnaya St., Saint Petersburg 191015
E. L. Dikareva
V.A. Almazov National Medical Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
2 Akkuratova St., Saint Petersburg 197341
A. D. Dzharbaeva
V.A. Almazov National Medical Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
2 Akkuratova St., Saint Petersburg 197341
O. A. Zhamborova
V.A. Almazov National Medical Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
2 Akkuratova St., Saint Petersburg 197341
T. M. Pervuninа
V.A. Almazov National Medical Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
2 Akkuratova St., Saint Petersburg 197341
E. V. Komlichenko
V.A. Almazov National Medical Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
2 Akkuratova St., Saint Petersburg 197341
S. A. Protsenko
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia
Russian Federation
Russian Federation
68 Leningradskaya St., Pesochny, Saint Petersburg 197758
G. M. Teletaeva
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia
Russian Federation
Russian Federation
68 Leningradskaya St., Pesochny, Saint Petersburg 197758
O. A. Li
V.A. Almazov National Medical Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
2 Akkuratova St., Saint Petersburg 197341
A. S. Artemyeva
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia
Russian Federation
Russian Federation
68 Leningradskaya St., Pesochny, Saint Petersburg 197758
I. A. Mashenko
V.A. Almazov National Medical Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
2 Akkuratova St., Saint Petersburg 197341
G. F. Kutusheva
V.A. Almazov National Medical Research Center, Ministry of Health of Russia
Russian Federation
Russian Federation
2 Akkuratova St., Saint Petersburg 197341
T. Yu. Semiglazova
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia; I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
А. F. Urmancheeva
N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia; I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
68 Leningradskaya St., Pesochny, Saint Petersburg 197758
41 Kirochnaya St., Saint Petersburg 191015
References
1. Ning F., Hou H., Morse A.N., Lash G.E. Understanding and management of gestational trophoblastic disease. F1000Res 2019;8:F1000 Faculty Rev-428.
2. Tidy J., Seckl M., Hancock B.W. et al. Management of gestational trophoblastic disease. BJOG 2021;128:e1–e27.
3. Ulrikh E.A., Teletaeva G.M., Latipova D.Kh. et al. Individualization in the treatment of resistant forms of gestational trophoblastic neoplasia. Voprosy onkologii = Problems in Oncology 2020;66(6):667–72. (In Russ.)
4. Ngan H.Y.S., Seckl M.J., Berkowitz R.S. et al. Update on the diagnosis and management of gestational trophoblastic disease. Int J Gynaecol Obstet 2018;143(Suppl 2):79–85.
5. Teletaeva G.M., Ulrikh E.A., Latipova D.Kh. et al. Successful experience in the treatment of high-risk gestational trophoblastic neoplasia in a patient with intolerance to standard chemotherapy (a case report). Opukholi zhenskoy reproduktivnoy systemy = Tumors of female reproductive system 2020;16(3):67–71. (In Russ.)
Review
For citations:
Ulrikh E.A., Dikareva E.L., Dzharbaeva A.D., Zhamborova O.A., Pervuninа T.M., Komlichenko E.V., Protsenko S.A., Teletaeva G.M., Li O.A., Artemyeva A.S., Mashenko I.A., Kutusheva G.F., Semiglazova T.Yu., Urmancheeva А.F. Trophoblastic neoplasia on the background of developing pregnancy: a rare gynecological tumor with a chance of favorable outcome for mother and fetus. Tumors of female reproductive system. 2022;18(3):112-117. (In Russ.) https://doi.org/10.17650/1994-4098-2022-18-3-112-117
Views:
404
Email this article 