Three-dimensional automated breast ultrasound – a supplemental screening tool

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Abstract

Background. Three-dimensional automated breast ultrasound (ABUS) is an innovative technology that allows global visualization of the breast and eliminates the operator-dependence of hand held ultrasound. Three-projection scanning during ABUS is provided by an ultra-long (15.4 cm) probe with a frequency of 14–16 MHz, and then the slices are reconstructed on a workstation. At the same time, high-frequency converters create high-resolution images. Through a special coronal projection, ABUS identifies variants of minimal, non-palpable breast cancer, including those with women with high mammographic breast density, which makes it a promising additional (supplemental screening) method of oncomammoscreening.
Aim. To assess the use of ABUS as a supplemental screening tool in women with high mammographic breast density.
Materials and methods. The study was conducted in 2018 at the N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia. As part of the study, 192 women underwent mammography, ABUS, and multiparametric ultrasound (B-mode, color Doppler, elatography) in standard manual mode.
Results. In the course of the study, in 192 patients, mammography revealed 42 cases of breast cancer, while using the AUS and manual ultrasound, additionally were identified 9 cases of breast cancer. Also, the ABUS showed high accuracy in assessment of the distribution of breast cancer – multifocal, multicentric and bilateral.
Conclusion. ABUS is a promising and highly effective diagnostic method in women with high mammographic breast density, with its advantages and disadvantages, which can be used in combination with mammography as a supplemental screening tool, especially in women at high risk of developing breast cancer.

About the authors

E. A. Busko

N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia;
Saint Petersburg State University

Author for correspondence.
Email: katrn@mail.ru
ORCID iD: 0000-0002-0940-6491

Ekaterina Aleksandrovna Busko 

68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758, Russia 

7–9 Universitetskaya Naberezhnaya, Saint Petersburg 199034, Russia 

Russian Federation

V. V. Semiglazov

N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia;
I.P. Pavlov First Saint Petersburg State Medical University

ORCID iD: 0000-0002-8825-5221

68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758, Russia

6–8 Lva Tolstogo St., Saint Petersburg 197022, Russia 

Russian Federation

N. I. Rozhkova

P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia;
Peoples’ Friendship University of Russia named after Patrice Lumumba

ORCID iD: 0000-0003-0920-1549

3 2-oy Botkinskiy Proezd, Moscow 125284, Russia;

6 Miklukho-Maklaya St., Moscow 117198, Russia 

Russian Federation

S. K. Dzhahilova

N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

ORCID iD: 0000-0003-0651-2499

68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758, Russia

Russian Federation

E. R. Akzyanova

N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

ORCID iD: 0000-0002-2213-7441

68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758, Russia

Russian Federation

P. V. Krivorotko

N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia

ORCID iD: 0000-0002-4898-9159

68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758, Russia 

Russian Federation

V. V. Ryazanov

Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia;
S.M. Kirov Military Medical Academy, Ministry of Defense of Russia

ORCID iD: 0000-0002-0037-2854

2A Litovskaya St., Saint Petersburg 194100, Russia;

6 Akademika Lebedeva St., Saint Petersburg 194044, Russia 

Russian Federation

S. S. Bagnenko

N.N. Petrov National Medical Research Oncology Center, Ministry of Health of Russia;
Saint Petersburg State Pediatric Medical University, Ministry of Health of Russia

ORCID iD: 0000-0002-4131-6293

68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758, Russia

2A Litovskaya St., Saint Petersburg 194100, Russia 

Russian Federation

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