There is nothing more obscure than the obvious fact: a case report of breast cancer associated with Peitz–Jeghers syndrome

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Abstract

This article provides a review of studies analyzing the etiology, diagnosis, and treatment of Peitz–Jeghers syndrome, as well as the risk of cancer of different locations in patients with this genetic disorder. We report a case of Peitz–Jeghers syndrome associated with breast cancer in young women in two generations (mother and daughter). Despite specific clinical manifestations (multiple hamartomatous polyps developing in childhood and ink-black mucous pigmentation in the woman and her immediate relatives), Peitz–Jeghers syndrome was diagnosed only after breast cancer development and consultation with oncologists. This confirms the need for informing both oncologists and general practitioners about this genetic disorder.

About the authors

N. A. Zaytsev

Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia

Author for correspondence.
Email: n.zaytsev.md@yandex.ru
ORCID iD: 0000-0002-7303-7213

Nikita Andreevich Zaytsev

Build. 1, 2/1 Barrikadnaya St., Moscow 125993

Russian Federation

I. V. Kolyadina

Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia; V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

ORCID iD: 0000-0002-1124-6802

Build. 1, 2/1 Barrikadnaya St., Moscow 125993; 4 Akademika Oparina St., Moscow 117997

Russian Federation

S. V. Khokhlova

Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia; V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

ORCID iD: 0000-0002-4597-172X

Build. 1, 2/1 Barrikadnaya St., Moscow 125993; 4 Akademika Oparina St., Moscow 117997

Russian Federation

V. V. Rodionov

V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

ORCID iD: 0000-0003-0096-7126

4 Akademika Oparina St., Moscow 117997

Russian Federation

I. V. Poddubnaya

Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia

ORCID iD: 0000-0002-0995-1801

Build. 1, 2/1 Barrikadnaya St., Moscow 125993

Russian Federation

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