Clinical and morphological characteristics of neuroendocrine tumors of female reproductive organs
https://doi.org/10.17650/1994-4098-2014-0-3-86-92
Abstract
The paper deals with the clinical and epidemiological features of human neuroendocrine tumors (NET) and those of female reproductive organs
in particular. It presents current approaches to classifying these neoplasms in relation to their embryogenesis and biological properties. The clinical and morphological features of NET of female genital organs are described in detail. Microscopic and immunohistochemical criteria
characterizing NET are also given.
About the Authors
T. Sh. Tagibova
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
S. O. Nikogosyan
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
O. A. Anurova
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
V. V. Kuznetsov
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
Z. N. Khizrieva
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
References
1. Симоненко В.Б., Дулин П.А., Маканин М.А. Нейроэндокринные опухоли. М., 2010. С. 6, 16.
2. Нейроэндокринные опухоли: руководство для врачей. Под ред. М. Кэплина, Л. Кволса. Пер. с англ. М.: Практическая медицина, 2011. с. 11, 17–19, 23, 37, 43, 54, 88, 100.
3. www.biochemmack.ru.
4. Jemal A., Murray T., Ward E., et al. Cancer statistics, 2005. CA Cancer J Clin 2005; 55(1):10–30.
5. Modlin I.M., Lye K.D., Kidd M. A 5-decade analysis of 13,715 carcinoid tumors. Cancer 2003;97(4):934–59.
6. Caplin M.E., Buscombe J.R., Hilson A.J. et al. Carcinoid tumour. Lancet 1998;352(9130):799–805.
7. Klimstra D.S., Modlin I.R., Adsay N.V. et al. Pathology reporting of neuroendocrine tumors: application of the Delphic consensus process to the development of a minimum pathology data set. Am J Surg Pathol 2010;34(3):300–13.
8. de Herder W.W., Krenning E.P., Van Eijck C.H., Lamberts S.W. Considerations concerning a tailored, individualized therapeutic management of patients with (neuro)-endocrine tumours of the gastrointestinal tract andpancreas. Endocr Relat Cancer 2004;11(1):19–34.
9. Volante M., Papotti M. Poorly differentiated thyroid carcinoma. 5 years after the 2004 WHO classification of endocrine tumours. Endocr Pathol 2010;21(1):1–6.
10. Eichhorn J.H., Young R.H. Neuroendocrine tumors of the genital tract. Am J Clin Pathol 2001;115 Suppl 1:S94–112.
11. Abeler V., Kjørstad K.E., Nesland J.M. Small cell carcinoma of the ovary. A report of six cases. Int J Gynecol Pathol 1988;7(4): 315–29.
12. Eichhorn J.H., Young R.H., Scully R.E. Primary ovarian small cell carcinoma of pulmonary type: a clinicopathologic, immunohistologic and flow cytometric analysis of 11 cases. Am J Surg Pathol 1992;16(10): 926–38.
13. Ambros R.A., Park J., Shah K., Kurman R.J. Evaluation of histologic, morphometric, and immunohistochemical criteria in the differential diagnosis of small cell carcinoma of the cervix with particular reference to human papillomavirus types 16 and 18. Mod Pathol 1991;4(5):586–93.
14. Groben P., Reddick R., Askin F. The pathologic spectrum of small cell carcinoma of the cervix. Int J Gynecol Pathol 1985;4(1): 42–57.
15. Gersell D.J., Mazoujian G., Mutch D.G., Rudloff M.A. Small-cell undifferentiated carcinoma of the cervix: a clinicopathologic, ultrastructural, and immunocytochemical study of 15 cases. Am J Surg Pathol 1988;12(9):684–98.
16. Huntsman D.G., Clement P.B., Gilks C.B., Scully R.E. Small cell carcinoma of the endometrium: a clinicopathologic study of sixteen cases. Am J Surg Pathol 1994;18(4): 364–75.
17. Miliauskas J.R., Leong A.S. Small cell (neuroendocrine) carcinoma of the vagina. Histopathology 1992;21(4); 371–4.
18. Husseinzadeh N., Wesseler T., Newman N. et al. Neuroendocrine (Merkel cell) carcinoma of the vulva. Gynecol Oncol 1988;29(1): 105–12.
Review
For citations:
Tagibova T.Sh., Nikogosyan S.O., Anurova O.A., Kuznetsov V.V., Khizrieva Z.N. Clinical and morphological characteristics of neuroendocrine tumors of female reproductive organs. Tumors of female reproductive system. 2014;(3):86-92. (In Russ.) https://doi.org/10.17650/1994-4098-2014-0-3-86-92
Views:
694
Email this article 