CO2 laser in the diagnostics of resection margins in breast tumors
https://doi.org/10.17650/1994-4098-2019-15-4-23-29
Abstract
To diagnostics of the evaporation of tumor tissue by radiation of single-mode medical CO2 laser is proposed a laser Doppler diagnostic method based on autodyne detection (reception on a laser resonator) of backscattered radiation from the evaporation zone. Intraoperative diagnostics of laser tissue evaporation lets surgeon to determine in real time tumour margins and evaporate it without additional normal tissue traumatization. The sensitivity limits of the method were studied on samples of malignant and benign tumors of breast together with plots of healthy tissue in vitro. It was shown that areas of tumor tissue are well determined by the autodyne method in 80 % of cases.
Supporting agencies: This work was supported by the Ministry of Science and Higher Education of Russia as part of the state assignment for Federal Scientific Research Centre “Crystallography and Photonics”, Russian Academy of Sciences, in terms of extracting the information component of the autodyne signal and the Russian Foundation for Basic Research Grant No. 18-29-02069-мк in terms of the diagnosis of neoplasms
About the Authors
A. I. Berishvili
University clinic High technology medical center
Russian Federation
Competing Interests: no conflict of interest
Russian Federation
9 Tsinandali St., Tbilisi 0128
Competing Interests: no conflict of interest
T. M. Kochoyan
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
Competing Interests: no conflict of interest
Russian Federation
23 Kashirskoe Shosse, Moscow 115478
Competing Interests: no conflict of interest
A. K. Dmitriev
Institute of Photon Technologies of Federal Scientific Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Russian Federation
Competing Interests: no conflict of interest
Russian Federation
2 Pionerskaya St., Troitsk 108840
Competing Interests: no conflict of interest
A. N. Konovalov
Institute of Photon Technologies of Federal Scientific Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Russian Federation
Competing Interests: no conflict of interest
Russian Federation
2 Pionerskaya St., Troitsk 108840
Competing Interests: no conflict of interest
V. A. Ulyanov
Institute of Photon Technologies of Federal Scientific Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Russian Federation
Competing Interests: no conflict of interest
Russian Federation
2 Pionerskaya St., Troitsk 108840
Competing Interests: no conflict of interest
А. G. Kedrova
Federal Research and Clinical Center for Specialized Medical Cares and Medical Technologies, Federal Biomedical Agency of Russia
Russian Federation
Competing Interests: no conflict of interest
Russian Federation
28 Orekhovyy Boulevard, Moscow 115682
Competing Interests: no conflict of interest
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Review
For citations:
Berishvili A.I., Kochoyan T.M., Dmitriev A.K., Konovalov A.N., Ulyanov V.A., Kedrova А.G. CO2 laser in the diagnostics of resection margins in breast tumors. Tumors of female reproductive system. 2019;15(4):23-29. (In Russ.) https://doi.org/10.17650/1994-4098-2019-15-4-23-29
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