Radio-induced breast angiosarcoma: features of diagnostics and treatment (a clinical case and literature review)

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Abstract

Breast angiosarcoma (BAS) is an extremely rare and poorly studied neoplasm, the etiology of primary BAS remains controversial, and secondary BAS is most often radio-induced. Radio-induced breast tumors usually appear 10–20 years after the initial treatment; however, for BAS this period is much shorter and is about 4–7 years. This review presents literature data on the features of the clinic, diagnosis and treatment of BAS, as well as own clinical case observation of radio-induced sarcoma of the left breast, that developed 4 years after the primary breast cancer treatment.

About the authors

I. V. Kolyadina

Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia; V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

Author for correspondence.
Email: irinakolyadina@yandex.com
ORCID iD: 0000-0002-1124-6802
2 / 1 Barrikadnaya St., Moscow 125993
4 Akademika Oparina St., Moscow 117198 Russian Federation

V. V. Kometova

V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

ORCID iD: 0000-0001-9666-6875
4 Akademika Oparina St., Moscow 117198 Russian Federation

Yu. V. Bikeev

V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

4 Akademika Oparina St., Moscow 117198 Russian Federation

S. V. Khokhlova

V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

4 Akademika Oparina St., Moscow 117198 Russian Federation

V. V. Rodionov

V.I. Kulakov National Medical Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of Russia

ORCID iD: 0000-0003-0096-7126
4 Akademika Oparina St., Moscow 117198 Russian Federation

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