Treatment results and prognostic factors of clear cell ovarian carcinomas and ovarian carcinomas with clear cell component

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Abstract

The most important prognostic factors for clear cell carcinoma (CCC) are clinical and morphological signs and clinical stage of the disease. Analyses of 5-year survival in patients with I stage of CCC is 69 %, in II stage – 55 %, in III stage – 14 % and in IV stage – 4 % patients. We analyzed distant results of treatment of 71 patients with CCC and of 25 patients with mixed malignant ovaries neoplasm with obligatory clear cell component taking into consideration main clinical and morphological sings of disease. On the base of performed reseal we revealed that morphological structure of the tumors and stage of the disease exerted heist influence on the exponent of survival of the patients with clear CCC ovaries neoplasm. Besides, there is a correlation between exponent of patients’ survival and radicalized of surgery, character of tumor growth, differentiation degree, cell anaplasia and mitotic activity of tumor cells.

About the authors

M. D. Ahmedova

Federal State Budgetary Institution N.N. Blokhin Russian Cancer Research Center under Russian Academy of Medical Sciences, Moscow

Russian Federation

M. A. Shabanov

Federal State Budgetary Institution N.N. Blokhin Russian Cancer Research Center under Russian Academy of Medical Sciences, Moscow

Russian Federation

V. V. Barinov

Federal State Budgetary Institution N.N. Blokhin Russian Cancer Research Center under Russian Academy of Medical Sciences, Moscow

Russian Federation

K. I. Zhordania

Federal State Budgetary Institution N.N. Blokhin Russian Cancer Research Center under Russian Academy of Medical Sciences, Moscow

Russian Federation

L. I. Bokina

Federal State Budgetary Institution N.N. Blokhin Russian Cancer Research Center under Russian Academy of Medical Sciences, Moscow

Russian Federation

E. A. Mustafina

Federal State Budgetary Institution N.N. Blokhin Russian Cancer Research Center under Russian Academy of Medical Sciences, Moscow

Author for correspondence.
Email: afl_nlo154@mail.ru
Russian Federation

I. I. Bokin

Federal State Budgetary Institution N.N. Blokhin Russian Cancer Research Center under Russian Academy of Medical Sciences, Moscow

Russian Federation

D. B. Olkin

Federal State Budgetary Institution N.N. Blokhin Russian Cancer Research Center under Russian Academy of Medical Sciences, Moscow

Russian Federation

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