Breast cancer risk factors assessment and BRCA-associated breast cancer evaluation in mammographic screening in India
https://doi.org/10.17650/1994-4098-2012-0-3-4-42-47
Abstract
Present article evaluate the influence of leading risk factors established for breast cancer (BC) on the mammography screening efficiency. 26 912 women underwent mammography screening in 2001−2010.
The direct impact of BC risk factor number on the disease stage was revealed. Diagnostic effectiveness of screening mammography decreased in patient groups with high mammographic density. The importance of control of patient groups with BC risk factors and reasonability of mam- mographic density evaluation is described.
The occurrence of BRCA1/2 mutations was revealed in patients with BC identified by mammography screening. The relationship between the presence of advanced and metastatic BC and the BRCA1/2 mutations was determined.
About the Authors
S. K. Ternovoy
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
S. Matkhev
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Saint Joseph Medical Centre, Cochin, India
Russian Federation
Russian Federation
A. E. Solopova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
K. A. Lesko
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
A. B. Abduraimov
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
References
1. Hofwind S., Sakshaug S., Ursin G., Graff-Iversen S. Breast cancer incidence trends in Norway – explained by hormone therapy or mammographic screening? Int J Cancer 2012;12(130):2930−38.
2. Kadiyala S., Strumpf E.C. Are United States and Canadian cancer screening rates consistent with guideline information regarding the age of screening initiation? Int J Qual Health Care 2011;6(23):611−20.
3. Злокачественные заболевания в России в 2010 году (заболеваемость и смертность). ФГБУ «МНИОИ им. П.А. Герцена Минздравсоцразвития России». Под ред. В.И. Чиссова, В.В. Старинского, Г.В. Петровой. М.: 2012. 260 с.
4. Porter P. «Westernizing» women's risks? Breast cancer in lower-income countries. N Engl J Med 2008;358;3:213−6.
5. Shah S., Gala F., Bhatnagar N. Breast cancer in India. Cancer Patient Aid Association. 2011. http://www. breastcancerindia.net/bc/ statistics/trends.htm.
6. Vaidyanathan K., Lakhotia S., Ravishankar H.M. et al. BRCA1 and BRCA2 germline mutation analysis among Indian women from south India: identification of four novel mutations and high-frequency occurrence of 185delAG mutation. J Biosci 2009;34(3):415−22.
7. Клиническая маммология (практическое руководство). Под ред. М.И. Давыдова, В.П. Летягина. М.: АБВ-пресс, 2010. С. 54−6.
8. Hardefeldt P.J., Eslick G.D., Edirimanne S. Benign thyroid disease is associated with breast cancer: a meta-analysis. Breast Cancer Res Treat 2012. http://www.ncbi.nlm.nih.gov/ pubmed/ 22434524.
9. Ditsch N., Liebhardt S., Von Koch F. et al. Thyroid function in breast cancer patients. Anticancer Res 2010;30:1713−7.
10. Angelousi A.G., Anagnostou V.K., Stamatakos M.K., Georgiopoulos G.C., Kontzoglou K.C. Primary Hypothyroidism and Risk for Breast Cancer: A Systematic Review and Meta-Analysis. Eur J Endocrinol 2012;166(3):373−81.
11. Cristofanilli M., Yamamura Y., Kau S.W. et al. Thyroid hormone and breast carcinoma. Primary hypothyroidism is associated with a reduced incidence of primary breast carcinoma. Cancer 2005;6(103):1122−8.
12. Assi V., Warwick J., Cuzick J., Duffy S.W. Clinical and epidemiological issues in mammographic density. Nat Rev Clin Oncol 2011;9(1):33−40.
13. Son B.H., Ahn S.H., Kim S.W. et al. Prevalence of BRCA1 and BRCA2 mutations in non-familial breast cancer patients with high risks in Korea: The Korean Hereditary Breast Cancer (KOHBRA) Study.
14. Breast Cancer Res Treat 2012. http://www. springerlink.com/content/l2859778823p6214/ fulltext.html.
Review
For citations:
Ternovoy S.K., Matkhev S., Solopova A.E., Lesko K.A., Abduraimov A.B. Breast cancer risk factors assessment and BRCA-associated breast cancer evaluation in mammographic screening in India. Tumors of female reproductive system. 2012;(3-4):42-47. (In Russ.) https://doi.org/10.17650/1994-4098-2012-0-3-4-42-47
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