Preview

Tumors of female reproductive system

Advanced search

The clinical-immunological analysis of a specific and combined immunotherapy of patients with cervical cancer

https://doi.org/10.17650/1994-4098-2012-0-3-4-147-150

Abstract

Research objective is the comparative assessment of efficiency of two various ways of an immunotherapy of patients with cervical cancer. 57 patients with cervical cancer, the III stages, distributed on 3 groups – combined radiotherapy, a combination of a radiotherapy and specific immunotherapy, and also a radiotherapy, specific and adaptive immunotherapy are surveyed. Clinical efficiency of treatment was estimated by means of primary tumor regression and 3-year survival rate. The scheme of combined immunotherapy was shown to possess the most clinical efficiency. Positive dynamics of cell immunity indicators was accompanied to clinical efficiency of treatment.

About the Authors

D. K. Kenbayeva
City Oncology Dispensary, Astana, Republic of Kazakhstan
Russian Federation


A. F. Lazarev
Altai Branch, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Barnaul
Russian Federation


References

1. Гуськова Е.А., Златник Е.Ю., Закора Г.И. Применение Ронколейкина и Реаферона для биотерапии рецидивного и генерализованного рака шейки матки. Росс биотерапевтич журнал 2008;7(1):39−40.

2. Танатова З.А. Особенности и повышение эффективности лечения злокачественных новообразований репродуктивной системы женщин в регионе Семипалатинского ядерного полигона. Автореф. дис. ... д-ра мед. наук. Астана, 2007; 44 с.

3. Bermúdez-Morales V.H., Peralta-Zaragoza O., Madrid-Marina V. Gene therapy with cytokines against cervical cancer. Salud Publica Mex 2005; 47(6);458−68.

4. Michelin M.A., Murta E.F. Potential therapeutic vaccine strategies and relevance of the immune system in uterine cervical cancer. Eur J Gynaecol Oncol 2008; 29(1):10−8.

5. Plate J. Clinical trials of vaccines for immunotherapy in pancreatic cancer. Expert Rev Vaccines 2011;10(6):825−36.


Review

For citations:


Kenbayeva D.K., Lazarev A.F. The clinical-immunological analysis of a specific and combined immunotherapy of patients with cervical cancer. Tumors of female reproductive system. 2012;(3-4):147-150. (In Russ.) https://doi.org/10.17650/1994-4098-2012-0-3-4-147-150

Views: 485


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 1994-4098 (Print)
ISSN 1999-8627 (Online)