Role of BRCA 1 и BRCA 2 gene mutations in the occurrence of male breast cancer
https://doi.org/10.17650/1994-4098-2011-0-1-29-31
Abstract
Particular emphasis has been recently placed on the mechanisms of carcinogenesis in breast cancer (BC), including those in male BC. The paper describes the major risk factors for BC in male patients and covers the role of BRCA1 and BRCA2 gene mutations in the occurrence of this pathology. The most important studies conducted in this area and their results are presented.
About the Authors
A. V. Bykova
Research Institute of Clinical Oncology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
I. K. Vorotnikov
Research Institute of Clinical Oncology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
Ya. V. Vishnevskaya
Research Institute of Clinical Oncology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
D. A. Denchik
Research Institute of Clinical Oncology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
L. N. Lyubchenko
Research Institute of Clinical Oncology, N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Russian Federation
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Review
For citations:
Bykova A.V., Vorotnikov I.K., Vishnevskaya Ya.V., Denchik D.A., Lyubchenko L.N. Role of BRCA 1 и BRCA 2 gene mutations in the occurrence of male breast cancer. Tumors of female reproductive system. 2011;(1):29-31. (In Russ.) https://doi.org/10.17650/1994-4098-2011-0-1-29-31
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