Role of magnetic resonance imaging in the diagnosis of recurrent cancer of the cervix uteri
https://doi.org/10.17650/1994-4098-2011-0-2-49-55
Abstract
Objective: to define a role of magnetic resonance imaging (MRI) in the follow-up of patients with cancer of the cervix uteri (CCU), who have undergone radiation therapy and chemoradiation therapy and to describe the types of the MRI pattern of recurrent CCU in the pelvic region.
Materials and methods. The results of a follow-up of 82 patients with a 4-47- (median 12 months) month history of invasive CCU were analyzed.
Results. Out of the 82 patients with invasive CCU, 25 were found to have pelvic recurrences; in 23 cases MRI revealed the latter (in the cervix uteri (n = 6), corpus uteri (n = 2), vagina (n = 2), parametrium (n = 2), iliac (n = 10), paraaortic (n = 5) lymph nodes, and pelvic wall (n=5).
Conclusion. The findings suggest that pelvic MRI is an effective technique to detect and estimate the extent of a pelvic recurrence and it is expedient to incorporate it into the scope of a follow-up after radiation therapy and chemoradiation therapy in patients with invasive CCU.
About the Authors
Z. N. Shavladze
Medical Radiology Research Center, Ministry of Health and Social Development of Russia, Obninsk
Russian Federation
Russian Federation
T. P. Berezovskaya
Medical Radiology Research Center, Ministry of Health and Social Development of Russia, Obninsk
Russian Federation
Russian Federation
A. A. Proshin
Medical Radiology Research Center, Ministry of Health and Social Development of Russia, Obninsk
Russian Federation
Russian Federation
L. I. Krikunova
Medical Radiology Research Center, Ministry of Health and Social Development of Russia, Obninsk
Russian Federation
Russian Federation
L. S. Mkrtchyan
Medical Radiology Research Center, Ministry of Health and Social Development of Russia, Obninsk
Russian Federation
Russian Federation
References
1. Злокачественные новообразования в России в 2008 году (заболеваемость и смертность). Под ред. В.И. Чиссова, В.В. Старинского, Г.В. Петровой. М.: МНИОИ им. П.А. Герцена, 2010.
2. Walsh J.W. Computed tomography of the pelvis. NY: Churchull Livingstone, 1985.
3. Burke T.W., Hoskins W.J., Heller P.B. et al. Clinical patterns of tumor recurrence after radical hysterectomy in stage IB cervical carcinoma. Obstet Gynecol 1987;69:382–5.
4. Manfredi R., Baltieri S., Tognolini A. Reccurrent uterine cancer after surgery: magnetic resonance imaging patterns and their changes after concomitant chemoradiation. Radiol Med 2008;113(8):1143–56.
5. Бохман Я.В. Руководство по онкогинекологии. СПб.: Фолиант, 2002.
6. Hille A., Weiss E., Hess C.F. Therapeutic outcome and prognostic factors in the radiotherapy of recurrences of cervical carcinoma following surgery. Strahlenther Onkol 2003;179(11):742–7.
7. Berek J.S., Novak E. Berek & Novak’s gynecology. 14th ed. Philadelphia: Lippincott Williams & Wilkins, 2007; p. 1441.
8. Березовская Т.П., Дьячков А.А., Валько- ва В.Н. Магнитно-резонансная томография при опухолях матки и придатков. Архангельск, 2002.
9. Zola P., Fuso L., Piovano E. еt al. Could follow-up different modalities play a role in asymptomatic cervical cancer relapses diagnosis? An Italian multicenter retrospective analysis. Gynecol Oncol 2007;107(1 Suppl 1):150–4.
10. Elit L., Fyles A.W., Devries M.C. et al. Follow-up for women after treatment for cervical cancer: a systematic review. Gynecol Oncol 2009;114(3):528–35.
11. Magne N., Chargari C., Devine C.E. et al. New trends in the evaluation and treatment of cervical cancer: the role of FDG-PET. Cancer Treat Rev 2008;43(8):671–81.
12. Yoon S.M., Shin K.H., Kim J.-Y. et al. Use of serum squamos cell carcinoma an-tigen for follow-up monitoring of cervical cancer patients who were treated by concur-rent chemoradiotherapy. Radiat Oncol 2010;5:78–83.
13. Saida T., Tanaka Y.O., Ohara K. et al. Can MRI predict local control of uterine cervical cancer immediately after radiation therapy? Magn Reson Med Sci 2010;9(3):141–8.
14. Jeong Y.Y., Kang H.K., Chung T.W. et al. Uterine cervical carcinoma after therapy: CT and MR imaging findings. Radiographics 2003;23:969–81.
15. Kaur H., Silverman P.M., Iyer R.B. et al. Diagnosis, staging, and surveillance of cervical carcinoma. Am J Roentgenol 2003;180:1621–32.
16. Wang J.Z., Mayr N.A., Zhang D. Sequential magnetic resonance imaging of cervical cancer: the predictive value of absolute tumor volume and regression ratio measured before, during, and after radiation therapy. Cancer 2010;116(21):5093–101.
17. Mayr N.A., Wang J.Z., Lo S.S. et al. Translating response during therapy into ultimate treatment outcame: a personalized 4-dimensional MRI tumor volumetric regression approach in cervical cancer. Int J Radiat Oncol Biol Phys 2010;76:719–27.
18. Weber T.M., Sostman D.H., Spritzer C.E. et al. Cervical carcinoma: determination of recurrent tumor extent versus radiation changes with MR imaging. Radiology 1995;194:135–9.
19. Kinkel K., Ariche M., Tardivon A.A. et al. Differentiation between recurrent tumor and benign conditions after treatment of gynecologic pelvic carcinoma: value of dynamic contrast-enhanced subtraction MR imaging. Radiology 1997;204:55–63.
20. Liyanage S.H., Roberts S.A., Rockall A.G. MRI and PET scan for primary staging and detection of cervical cancer reccurence. Women’s Health 2010;6(2):251–69.
Review
For citations:
Shavladze Z.N., Berezovskaya T.P., Proshin A.A., Krikunova L.I., Mkrtchyan L.S. Role of magnetic resonance imaging in the diagnosis of recurrent cancer of the cervix uteri. Tumors of female reproductive system. 2011;(2):49-55. (In Russ.) https://doi.org/10.17650/1994-4098-2011-0-2-49-55
Views:
658
Email this article 