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Comparative characterization of oxidative stress in cervical cancer at different clinical stages of disease
- Authors: Antoneeva I.I.1, Gening T.P.1, Arslanova D.R.1, Sidorenko E.G.1
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Affiliations:
- Ulyanovsk State University
- Issue: No 4 (2011)
- Pages: 55-58
- Section: GYNECOLOGY. PROBLEM
- Published: 18.11.2011
- URL: https://ojrs.abvpress.ru/ojrs/article/view/198
- DOI: https://doi.org/10.17650/1994-4098-2011-0-4-55-58
- ID: 198
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Abstract
Parameters of oxidative stress on the level of malondialdehyde (MDA), activity of glutathione-reductase, glutathione-transferase, superoxide- dismutase (SOD) and catalase in tumor tissue, plasma and red blood cells of patients with cervical cancer (CC) w as evaluated a t various clinical stages of the disease. It is revealed that an increase in tumor tissue MD A and glutathione enzymes while reducing SOD and catalase, which may indicate the development of oxidative stress in the dynamics of tumor progression. The data obtained suggest the increase of expres- sion of oxidative stress in red blood cells and tumor tissue in CC in the dynamics of tumor progression.
About the authors
I. I. Antoneeva
Ulyanovsk State University
Author for correspondence.
Email: Naum-53@yandex.ru
Russian Federation
T. P. Gening
Ulyanovsk State UniversityRussian Federation
D. R. Arslanova
Ulyanovsk State UniversityRussian Federation
E. G. Sidorenko
Ulyanovsk State UniversityRussian Federation
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