New verification possibilities for ovarian malignancies

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Abstract

The fact that the diagnosis can be significantly verified using the liquid-based cytology technique and immunocytochemical assa
in analyzed 72 cases with the ascites forms of ovarian cancer. The effective panel to diagnose ovarian adenocarcinomas with ascites may be considered as follows: Ber-EP4, calretinin for the differential diagnosis of the tumor with reactive changes, as well as estrog en receptors, WT-1, CK7 for the clarification of the type of adenocarcinoma (in case of a positive reaction to Ber-EP4). Verification of the mucinous form of adenocarcinoma is now made difficult by a negative reaction to organ-specific markers.

About the authors

A. E. Protasova

Department of Oncology, Moscow Academy of Postgraduate Education; Medical Faculty, State University; City Clinical Oncology Dispensary, Saint Petersburg

Author for correspondence.
Email: Protasova1966@yandex.ru
Russian Federation

R. V. Orlova

Department of Oncology, Moscow Academy of Postgraduate Education; Medical Faculty, State University; City Clinical Oncology Dispensary, Saint Petersburg

G. A. Raskin

Department of Oncology, Moscow Academy of Postgraduate Education; Medical Faculty, State University; City Clinical Oncology Dispensary, Saint Petersburg

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