Changes in angiogenesis markers during neoadjuvant treatment for locally advanced breast cancer

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Abstract

The impact of various neoadjuvant treatment regimens on the level of enzyme immunoassay-determined angiogenic markers of endothelial growth factor and its type 2 receptor in tumor cytosol and serum was assessed in 30 patients with locally advanced breast cancer (BC). The findings suggest the promises for studies of neoangiogenesis factors mainly in tumor tissue for their possible use as prognostic biological markers in patients with BC.

About the authors

E. A. Kim

I.M. Sechenov Moscow Medical Academy

Author for correspondence.
Email: helene-kim@yandex.ru
Russian Federation

I. V. Vysotskaya

I.M. Sechenov Moscow Medical Academy

Russian Federation

N. E. Kushlinsky

N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow

Russian Federation

V. P. Letyagin

N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow

Russian Federation

E. S. Gershtein

N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow

Russian Federation

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