Specific features of the clinical picture, diagnosis, and treatment of trophoblastic tumor of the placental bed

D. A. Lisaev; Лисаев Д. А.; B. O. Toloknov; Толокнов Б. О.; E. E. Makhova; Махова Е. Е.; T. I. Zakharova; Захарова Т. И.; I. V. Markina; Маркина И. В.

doi:10.17650/1994-4098-2010-0-1-63-67

Specific features of the clinical picture, diagnosis, and treatment of trophoblastic tumor of the placental bed

Authors: Lisaev D.A.¹^,2, Toloknov B.O.¹^,2, Makhova E.E.¹^,2, Zakharova T.I.¹^,2, Markina I.V.¹^,2
Affiliations:
1. N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences
2. Department of Oncology, Moscow State University of Medicine and Dentistry
Issue: No 1 (2010)
Pages: 63-67
Section: GYNECOLOGY. DIAGNOSIS
Published: 25.02.2010
URL: https://ojrs.abvpress.ru/ojrs/article/view/219
DOI: https://doi.org/10.17650/1994-4098-2010-0-1-63-67
ID: 219

Cite item

Full Text

Abstract
About the authors
References
Supplementary files
Statistics

Abstract

Trophoblastic tumor of the placental bed is a highly malignant form of trophoblastic disease that occurs extremely rarely: 0.4-2% of all the trophoblastic tumors. In the world literature, there are reports on about 200 cases of this disease. The tumor occurs at a repro- ductive age (median age 30 years), occasionally even long after pregnancy, which makes the problem of diagnosis and treatment of the pathology particularly pressing. In 30% of cases, there are metastases more frequently to the lung and vagina. The diagnostic features of a placental bed tumor include the low serum levels of chorionic gonadotropin β-subunits and the higher level of human placental lactogen. Due to low tumor susceptibility to chemotherapy, the patients should undergo surgical intervention as uterine extirpation at the first treatment stage, which is followed by chemotherapy.

Keywords

trophoblastic tumor of the placental bed, human placental lactogen.

References

Supplementary files

Supplementary Files

Action

1. JATS XML

Download

Username
Password
Remember me

Forgot password?	Register

Username
Password
Remember me

Forgot password?	Register

Specific features of the clinical picture, diagnosis, and treatment of trophoblastic tumor of the placental bed

Full Text

Abstract

Keywords

About the authors

D. A. Lisaev

B. O. Toloknov

E. E. Makhova

T. I. Zakharova

I. V. Markina

References

Supplementary files