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Molecular biological factors in the diagnosis of cervical intraepithelial neoplasias
- Authors: Ponomareva Y.N.1, Manukhin I.B.2, Ashrafyan L.A.3
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Affiliations:
- Moscow Regional Hospital Five
- Department of Obstetrics and Gynecology, Moscow State University of Medicine and Dentistry
- Russian X-ray Radiology Research Center, Russian Agency for Medical Technologies, Moscow
- Issue: No 1 (2010)
- Pages: 72-75
- Section: GYNECOLOGY. NEW TECHNOLOGIES
- Published: 25.02.2010
- URL: https://ojrs.abvpress.ru/ojrs/article/view/221
- DOI: https://doi.org/10.17650/1994-4098-2010-0-1-72-75
- ID: 221
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Abstract
The authors have made a complex analysis of the molecular biological factors associated with cervical intraepithelial neoplasia. They have revealed that infection by oncogenic human papillomavirus types is associated with suppressed apoptosis and enhanced cellular proliferative activity, which can be effectively used in the diagnosis and prediction of cervical neoplasias to optimize management tac- tics and to improve the results of treatment.
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About the authors
Yu. N. Ponomareva
Moscow Regional Hospital FiveRussian Federation
I. B. Manukhin
Department of Obstetrics and Gynecology, Moscow State University of Medicine and DentistryRussian Federation
L. A. Ashrafyan
Russian X-ray Radiology Research Center, Russian Agency for Medical Technologies, Moscow
Author for correspondence.
Email: mailbox@rncrr.rssi.ru
Russian Federation
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